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Mortality patterns in older adults with infective endocarditis in the US: A retrospective analysis
Published 2024“…<h3>Background</h3><p dir="ltr">Infective Endocarditis (IE) has become a significant cause of morbidity and mortality over the last two decades. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Microbiome profiling of rotavirus infected children suffering from acute gastroenteritis
Published 2022“…Microbial dysbiosis caused by RV infection may significantly influence disease prognosis and the development of other chronic diseases. …”
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Pattern of Postoperative Mortality After Esophageal Cancer Resection According to Center Volume
Published 2015“…The aim of this study was to define the pattern of POM and major morbidity in relation to center procedural volume. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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Geographical Patterns of HIV Sero-Discordancy in High HIV Prevalence Countries in Sub-Saharan Africa
Published 2016“…Conversely, there was a negative, but weak and not significant, correlation between HIV prevalence and the proportion of SDPs among all stable couples with at least one HIV-infected individual in the partnership. …”
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Molecular Characterization and Genotyping of Multi-drug Resistant Uropathogenic Escherichia coli
Published 2023“…While females are disproportionately affected, there remains a significant gap in the understanding of gender-based genotypic variations in E. coli causing urinary tract infections. …”
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Asymptomatic COVID-19 presenting with features of mixed pattern acute liver injury in a young healthy female, a case report
Published 2023“…We want to report a case of acute liver injury of mixed pattern in a young healthy female with asymptomatic COVID-19 infection. …”
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Whole-Genome Molecular Characterization and Typing of Staphylococcus aureus Isolated from Lebanon
Published 2020“…Staphylococcus aureus is one of the major causes of nosocomial and community-acquired infections. The rising prevalence of multidrug resistant (MDR) S. aureus in both community and hospital settings is a significant public health concern. …”
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SARS‐CoV‐2 infection and effects of age, sex, comorbidity, and vaccination among older individuals: A national cohort study
Published 2023“…Risk of infection varied minimally by age and sex but increased significantly with coexisting conditions. …”