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increased » increase (Expand Search)
decrease » increase (Expand Search)
interaction » integration (Expand Search)
prediction » reduction (Expand Search), production (Expand Search)
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Detection of statistically significant network changes in complex biological networks
Published 2017“…</p><h3>Methods</h3><p dir="ltr">In this paper, we propose an improvement over the state-of-the-art based on the Generalized Hamming Distance adopted for evaluating the topological difference between two networks and estimating its statistical significance. The proposed procedure exploits a more effective model selection criteria to generate <i>p</i>-values for statistical significance and is more efficient in terms of computational time and prediction accuracy than literature methods. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Malignant peritoneal mesothelioma interactome with 417 novel protein–protein interactions
Published 2024“…</p><h3 dir="ltr">Methods</h3><p dir="ltr">We constructed the protein interactome of 59 MPeM-associated genes with previously known protein-protein interactions (PPIs) as well as novel PPIs predicted using our previously developed HiPPIP computational model and analysed it for transcriptomic and functional associations and for repurposable drugs.…”
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Model predictive control of shell benchmark process
Published 2003“…MPC technology has penetrated a significant portion of the process industries and harvested large economical benefits. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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Characterization of the dynamic flow response in microfluidic devices
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NOVEL STACKING CLASSIFICATION AND PREDICTION ALGORITHM BASED AMBIENT ASSISTED LIVING FOR ELDERLY
Published 2022“…The primary objective of this thesis is to identify the fall detection and prediction in older persons, such as 0 - no fall detected, 1 - person slipped/tripped / fall prediction, and 2 - definite fall. …”
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Prediction of critical total drawdown in sand production from gas wells: Machine learning approach
Published 2023“…The effects of all independent variables on the CTD are displayed in three-dimensional plots and showed significant interactions.</p> </div><p></p><h2>Other Information</h2> <p> Published in: The Canadian Journal of Chemical Engineering<br> License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1002/cjce.24640" target="_blank">http://dx.doi.org/10.1002/cjce.24640</a></p>…”
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Machine Learning Techniques for Pharmaceutical Bioinformatics
Published 2018“…This dissertation presents a novel drug classifier to automate the prediction of drug indication and drug interactions with other drugs. …”
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Suboptimal dietary knowledge predicts lower diet quality for cancer prevention among university students in Beirut
Published 2025“…Increased knowledge (B = 0.78, 95%CI: 0.18,1.37) and high physical activity (B = 4.62, 95%CI: 1.66,7.59) were associated with elevated AHEI scores. A significant positive interaction was observed between knowledge and enrollment in a health-related major. …”
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Semi-analytical Model to Predict Dynamic Capillary Pressure–Saturation Relationship for Flows in Heterogeneous Porous Media
Published 2024“…After performing a holistic sensitivity analysis, we notice that the properties of the porous medium, and the fluid–solid interactions play a significant role in defining the trends of the capillary pressure–saturation curves.…”
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Hyperspectral-physiological based predictive model for transpiration in greenhouses under CO<sub>2</sub> enrichment
Published 2023“…The results demonstrated the inclusion of hyperspectral-based vegetation indices significantly increased the performance of the three machine learning models in predicting transpiration. …”