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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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EEG-Based Multi-Level Mental State Classification Using Partial Directed Coherence and Graph Convolutional Networks: Impact of Binaural Beats on Stress Mitigation
Published 2025“…Mental states were assessed using behavioral data: reaction time to stimuli (RT) and target detection accuracy, subjective reports: Perceived Stress Scale scores (PSS-10), biochemical indicators: salivary cortisol levels, and neurophysiological measure: EEG effective connectivity via Partial Directed Coherence (PDC). BBs significantly improved target detection accuracy by 31.6% and 22.8% for low and high-stress groups, respectively. …”
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Pspice double void partial discharge simulation and detection using wavelet
Published 2003“…Partial Discharges (PD) on insulation in general is among the most vulnerable processes in the AC system that can cause a failure. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Classification of Common Partial Discharge Types in Oil-Paper Insulation Using Acoustic Signals
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Stress Management Using Physiological Signals and Audio Stimulation
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Brain Connectivity Analysis Under Semantic Vigilance and Enhanced Mental States
Published 2019“…The results show that PDC is very sensitive to vigilance decrement and shows that the brain connectivity network is significantly reduced with increasing TOT, p < 0.05. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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EEG-Based Semantic Vigilance Level Classification Using Directed Connectivity Patterns and Graph Theory Analysis
Published 2020“…The strength and directionality of information flow in the connectivity network by RWTE/PDC and the GTA measures significantly decrease with vigilance decrement, p<0.05. …”
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Modeling Human Resource Training Using Social Network Theory and Analytics
Published 2022“…Data were collected from 130 employees who have undergone training at their workplace in the past. Results from social network analysis and partial least squares path modelling show that the social network variables of betweenness, efficiency and tie strength positively impact training, while density and degree have no significant impact. …”
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Dual-stage segmentation and classification framework for skin lesion analysis using deep neural network
Published 2025“…<h3>Objective</h3><p dir="ltr">Skin diseases, caused by various pathogens including bacteria, viruses, and fungi, are prevalent globally and significantly affect patients’ physical, emotional, and social well-being. …”
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Enhancing fairness and scalability in IOTA tangle networks: a POMDP-based tip selection algorithm for decentralized systems
Published 2025“…This study presents a novel Partially Observable Markov Decision Process (POMDP)-based Tip Selection Algorithm (TSA) to optimize fairness in the IOTA Tangle. …”