-
1
-
2
-
3
-
4
-
5
The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
-
6
Cluster-based anonymity model and algorithm for 1:1 dataset with a single sensitive attribute using machine learning technique
Published 2024“…Privacy-preserving data publishing is significant as privacy violations in the patient’s data may have an adverse effect on the individual positive reputation. …”
-
7
-
8
A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
-
9
-
10
Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
-
11
Dynamic single node failure recovery in distributed storage systems
Published 2017“…The third extension is addressed by implementing variable fractional repetition codes which is shown to achieve significant cost reduction. The contributions of the paper are four fold: (i) generating an optimized block distribution scheme among the nodes of a given data center for fixed and variable size blocks; (ii) optimization of storage allocation under dynamic environments with data block arrivals; (iii) optimization of storage allocation with newly added storage nodes; and (iv) generating an effective block distribution scheme among the nodes by accounting for varying priorities among data blocks. …”
Get full text
Get full text
Get full text
Get full text
article -
12
Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
Get full text
Get full text
Get full text
article -
13
Variational Auto Encoder Approach To Find Deferentially Expressed Genes
Published 2022“…A study of differentially expressed genes across different cell types will help in identifying cell-specific responses to treatments or diseases. Recent advances in single-cell technology enable an analysis of thousands of cells which brought lots of computational challenges in terms of noise in the data sets and required computational power to handle the big data. …”
Get full text
-
14
Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
Get full text
Get full text
Get full text
article -
15
Effect of Climate Change on the Energy Performance and Thermal Conditions of a Single-family Detached House in Canada
Published 2019“…However, with the changing climate how these buildings designed based on historical weather data would perform under future climates. This paper attempts to answer this question by investigating the effect of climate change on the energy demand and overheating risk in a single-family detached house with different energy efficiency levels, i.e. …”
Get full text
Get full text
-
16
-
17
-
18
Comparison of Single‐Coil Versus Dual‐Coil Implantable Cardioverter Defibrillator Devices: A Systematic Review and Meta‐Analysis of Efficacy and Extraction‐Related Outcomes
Published 2025“…This updated systematic review and meta‐analysis compares the efficacy and extraction‐related outcomes of single‐coil versus dual‐coil ICDs in view of conflicting data.…”
-
19
-
20
Comparative Study of Deep Learning Models for Unimodal & Multimodal Disaster Data for Effective Disaster Management
Published 2021“…Many studies focus only on the text modalities, single classification tasks and small-scale home-grown datasets when studying how useful social media data can be for emergency services. …”
Get full text
