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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Variational Auto Encoder Approach To Find Deferentially Expressed Genes
Published 2022“…Recently, deep learning models such as Autoencoder (AE) and Variational Autoencoder (VAE) models are being used to capture hidden patterns from single-cell gene expression data. …”
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Variation of Shear Wave Velocity with SPT-N Values in the City of Sharjah
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Artificial Intelligence Frameworks for Sentiment Variations’ Reasoning and Emerging Topic Detection
Published 2021“…This model can be used for multiple applications, including detection of new research trends from large sets of scientific papers, discovery of hot topics on social media, comparison of customer reviews for two products to identify their strong/weak aspects, and our focus topic of interpreting public sentiment variations. …”
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Using Artificial Intelligence to Understand What Causes Sentiment Changes on Social Media
Published 2021“…Then we present a Filtered-LDA framework that significantly outperformed existing methods of interpreting sentiment variations on Twitter. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Micro-Expression Recognition using Convolutional Variational Attention Transformer (ConVAT) with Multihead Attention Mechanism
Published 2025“…To address these limitations, we propose the Convolutional Variational Attention Transformer (ConVAT), a novel model that leverages a multi-head attention mechanism integrated with convolutional networks, optimized specifically for detailed micro-expression analysis. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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Technical Note: Investigating of dosimetric leaf gap and leaf transmission factor variations across gantry and collimator angles in volumetric modulation arc therapy
Published 2024“…</p><h3>Results</h3><p dir="ltr">LTF values showed no significant variation across gantry and collimator angles. …”
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Ventilation System Modelling and Turbulence Minimisation
Published 2014“…Analytical procedures enabling the construction of simple, compact models including the relatively pointwise and significantly distributed system elements are proposed. …”
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Dynamics of Neisseria gonorrhoeae transmission among female sex workers and clients: A mathematical modeling study
Published 2024“…Increasing symptomatic treatment coverage among FSWs from 0 % to 100 % decreases prevalence from 10.6 % to 4.5 %, 0.8 % to 0.4 %, and 0.3 % to 0.1 %, respectively. …”
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