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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Encapsulation and Release of Calcein from Herceptin-conjugated eLiposomes
Published 2023Get full text
doctoralThesis -
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Light-Responsive Metal-Organic Frameworks (MOFs) For Doxorubicin Controlled Release
Published 2023Get full text
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Ultrasound triggered release of Trastuzumab-conjugated immunoliposomes targeting breast cancer
Published 2018Get full text
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Dynamics of Chemotherapeutic Drug Release from Liposomes Using Low-Frequency Ultrasound
Published 2015Get full text
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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In vivo testing of novel nitric oxide-releasing nanoparticles for alleviating heart failure using the zebrafish embryo model
Published 2024“…Our findings demonstrated that the NO-RPs improved the survival rate in the heart failure zebrafish model and reversed heart failure by enhancing blood flow perfusion in Zebrafish embryos, significantly. In addition, RT-PCR results showed that the NO-RPs significantly reduced the expression of pro-inflammatory markers (lL-6&COX-2) in the heart failure zebrafish model. …”
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In vivo testing of novel nitric oxide-releasing nanoparticles for alleviating heart failure using the zebrafish embryo model
Published 2024“…Our findings demonstrated that the NO-RPs improved the survival rate in the heart failure zebrafish model and reversed heart failure by enhancing blood flow perfusion in Zebrafish embryos, significantly. In addition, RT-PCR results showed that the NO-RPs significantly reduced the expression of pro-inflammatory markers (lL-6&COX-2) in the heart failure zebrafish model. …”
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Anti-hypertrophic effect of Na+/H+ exchanger-1 inhibition is mediated by reduced cathepsin B
Published 2020“…Cat B proteases are released into the cytoplasm upon disintegration of the lysosomes. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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Enhancing Curcumin’s therapeutic potential in cancer treatment through ultrasound mediated liposomal delivery
Published 2024“…Targeted delivery and sustained release of therapeutic drugs to cancer cells can reduce the whole-body cytotoxicity of the agent and deliver a safe localized treatment to the patient. …”
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Hybrid sorption thermal–battery storage in photovoltaic greenhouses: Toward net-zero energy and reduced battery stress
Published 2026“…Sorption Thermal Energy Storage (SoTES) can capture and release excess heat with high efficiency, offering long-term thermal savings and significant cooling load reduction. …”
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Anti-hypertrophic effect of Na<sup>+</sup>/H<sup>+</sup> exchanger-1 inhibition is mediated by reduced cathepsin B
Published 2020“…Cat B proteases are released into the cytoplasm upon disintegration of the lysosomes. …”
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Research on the potential of photovoltaic technologies in reducing energy consumption in an urban mixed use residential community. A Case study for net zero energy community in Dub...
Published 2018“…Accelerated global economic and population growth are the main influencing factors that has led to the increase in electricity consumption. In addition, the release greenhouse gas (GHG) emissions from energy resources such as the fast depleting fossil fuels whose prices are rising globally. …”
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