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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications
Published 2025“…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …”
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Risk of post-ERCP pancreatitis with placement of self-expandable metallic stents
Published 2010“…When significant variables were added to a multiple-predictor regression model, the odds of PEP from SEMS placement increased to 6.8 (95% CI, 2.2, 21.4). …”
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Maternal and Neonatal Outcomes Post Bariatric Surgery: A Population-Based Study
Published 2023“…P value was regarded as significant at <0.05</p> <h3>Results</h3> <p>Qatari, advanced maternal age, Parity >1, diabetes, and hypertension were found to be significant risk factors for women with post-BS.…”
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Analyzing hydrodynamic changes in the Dubai Creek: a pre- and post-extension study
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Cardiovascular impact of post-traumatic stress disorder: A systematic review and meta-analysis
Published 2024“…<h3>Background</h3><p dir="ltr">Post-traumatic stress disorder (PTSD) is increasingly recognized for its effects beyond mental health, with emerging evidence suggesting a significant association with cardiovascular diseases (CVD). …”
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Post‐Operative Analgesics Score, Another Tool in the Quest for a Better Pain Management
Published 2023“…This holds true especially in inguinal hernia surgery, an area where the confluence of three nerves and their surgical handling are associated with a significant incidence of debilitating chronic post-inguinal surgery pain (CPIP). …”
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NMT verb rendering: A cognitive approach to informing Arabic-into-English post-editing
Published 2022“…<p>Machine translation (MT) has made significant strides and has reached accuracy levels that often make the post-editing (PE) of MT output a viable alternative to manual translation. …”
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Necrotizing Soft Tissue Infection Post VASER-Assisted Liposuction and Lipofilling: A Case Report
Published 2023“…The complication rate is very minimal, and it increases relatively when combined with other procedures. …”
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…While most PDAs close after one 3-day course of either medicine, a repeat course may be necessary before considering surgical ligation for those who remain with hsPDAs. In our practice, we administer one or two courses of ibuprofen followed by a single course of indomethacin if the PDA has not shown closure or decrease in size on the echocardiogram (echo) exam. …”
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The Association Between Childhood Maltreatment and Post-Traumatic Stress Disorder (PTSD) Among Young Adults in Northern Syria
Published 2025“…Furthermore, exposure to emotional abuse in childhood significantly increased the probability of developing PTSD in adulthood (Odds ratio [OR], 0.7; 95% [CI], 0.5–0.9, <i>P</i> <.01). …”