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Prevalence and clinical significance of antiphospholipid antibodies in patients with coronavirus disease 2019 admitted to intensive care units: a prospective observational study
Published 2022“…Although the presence of antiphospholipid antibodies (aPLs) has been proposed as a possible mechanism of COVID-19-induced coagulopathy, its clinical significance remains uncertain. …”
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Photobiomodulation Suppresses Alpha-Synuclein-Induced Toxicity in an AAV-Based Rat Genetic Model of Parkinson’s Disease
Published 2015“…In the present study, we report that chronic PMB treatment mitigates dopaminergic loss induced by unilateral overexpression of human α-synuclein (α-syn) in the substantia nigra of an AAV-based rat genetic model of Parkinson’s disease (PD). …”
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Sestrin2 as a Novel Biomarker and Therapeutic Target for Various Diseases
Published 2017“…Thus, the aim of this review is to discuss the upstream regulators and the downstream effectors of Sestrins and to highlight the significance of Sestrin2 as a biomarker and a therapeutic target in diseases such as metabolic disorders, cardiovascular and neurodegenerative diseases, and cancer.…”
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Detection of statistically significant network changes in complex biological networks
Published 2017“…The ability to detect statistical relevant changes in the interaction patterns induced by the progression of the disease can lead to the discovery of novel relevant signatures. …”
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Klotho overexpression protects human cortical neurons from β-amyloid induced neuronal toxicity
Published 2025“…These neurons were next exposed to pre-aggregated β-amyloid 1–42 oligomers to model the neurotoxicity associated with Alzheimer’s disease. Our data reveal that upregulation of <i>KLOTHO</i> significantly reduced β-amyloid-induced neuronal degeneration and apoptosis, as evidenced by decreased cleaved caspase-3 expression and preservation of axonal integrity. …”
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Efficacy of Lebanese Cannabis Oil Extract in the Treatment of Folic Acid-Induced Renal Fibrosis in Rats
Published 2023“…Kidney disease is a main contributor to mortality and morbidity worldwide. …”
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Systemic Inflammation May Induce Cardiac Injury in COVID-19 Patients Including Children and Adolescents Without Underlying Cardiovascular Diseases: A Systematic Review
Published 2022“…Increasing amounts of evidence suggest that a system-wide inflammatory response and a cytokine storm mediated type syndrome plays a crucial role in disease progression. This systematic review investigates the possible role of hyperinflammation in inducing cardiac injury as one of the severe complications of COVID-19. …”
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Investigation of the Effect of Exendin-4 on Oleic Acid-Induced Steatosis in HepG2 Cells Using Fourier Transform Infrared Spectroscopy
Published 2022“…FTIR and chemometric analyses revealed that Ex-4 significantly reduces OA-induced lipid accumulation, and Ex-4 also restored the lipid and protein biochemical alterations caused by lipotoxicity-induced oxidative stress. …”
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Cold responses and hormonal echoes: a comprehensive view of Raynaud’s vascular dysfunction
Published 2025“…Interestingly, Raynaud’s phenomenon incidence is significantly higher in premenopausal females compared to age-matched males, highlighting a role of the female hormone, estrogen, in Raynaud’s phenomenon pathogenesis. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Local arterial vasoconstriction induced by octreotide in patients with cirrhosis
Published 2000“…Octreotide probably has a facilitating effect over vasoconstrictors increased in chronic liver diseases…”
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Revealing the Adoption Factors of Electric Vehicles in Dubai
Published 2024“…By using descriptive statistics, correlation analysis, and regression analysis, our findings indicate a significant association between the willingness to adopt EVs and several factors, including the performance characteristics and economic cost. …”
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Metabolic Profiling of Exercise-induced Autophagy-dependent Metabolites in Mouse Plasma
Published 2024“…This study demonstrates the significant changes in the plasma metabolome induced by exercise, which are partially mediated by autophagy. …”
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Driving simulation sickness and the sense of presence: Correlation and contributing factors
Published 2021“…Simulation sickness (SS) and the sense of presence (SP) are two well-known factors that could affect the results of the driving simulator experiments. …”
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Kounis syndrome: acute myocardial injury triggered by ant bite-induced anaphylaxis
Published 2025“…Coronary angiography and cardiac MRI were unremarkable, ruling out significant coronary artery disease. The patient was diagnosed with Kounis syndrome and discharged with an EpiPen and instructions for anaphylaxis management. …”
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Cardioprotective effect of Sanguisorba minor against isoprenaline-induced myocardial infarction in rats
Published 2023“…Histopathological studies of the cardiac tissue showed isoprenaline-induced injury that was significantly attenuated by the extract.…”
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Plant Leaf Disease Detection Using Ensemble Learning and Explainable AI
Published 2024“…Much like human health, plants face susceptibility to diseases induced by viruses and bacteria, necessitating careful attention to plant care and disease identification. …”
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Burden and disease pathogenesis of influenza and other respiratory viruses in diabetic patients
Published 2022“…Vaccinating diabetic patients against influenza would significantly reduce hospitalization due to disease severity. …”
