Prevalence and clinical significance of antiphospholipid antibodies in patients with coronavirus disease 2019 admitted to intensive care units: a prospective observational study by Mostafa Najim (14150400)

“…Although the presence of antiphospholipid antibodies (aPLs) has been proposed as a possible mechanism of COVID-19-induced coagulopathy, its clinical significance remains uncertain. …”

Photobiomodulation Suppresses Alpha-Synuclein-Induced Toxicity in an AAV-Based Rat Genetic Model of Parkinson’s Disease by Abid Oueslati (816135)

“…In the present study, we report that chronic PMB treatment mitigates dopaminergic loss induced by unilateral overexpression of human α-synuclein (α-syn) in the substantia nigra of an AAV-based rat genetic model of Parkinson’s disease (PD). …”

Sestrin2 as a Novel Biomarker and Therapeutic Target for Various Diseases by Mazhar Pasha (11197767)

“…Thus, the aim of this review is to discuss the upstream regulators and the downstream effectors of Sestrins and to highlight the significance of Sestrin2 as a biomarker and a therapeutic target in diseases such as metabolic disorders, cardiovascular and neurodegenerative diseases, and cancer.…”

Detection of statistically significant network changes in complex biological networks by Raghvendra Mall (581171)

“…The ability to detect statistical relevant changes in the interaction patterns induced by the progression of the disease can lead to the discovery of novel relevant signatures. …”

Klotho overexpression protects human cortical neurons from β-amyloid induced neuronal toxicity by Mohammed R. Shaker (10316180)

“…These neurons were next exposed to pre-aggregated β-amyloid 1–42 oligomers to model the neurotoxicity associated with Alzheimer’s disease. Our data reveal that upregulation of <i>KLOTHO</i> significantly reduced β-amyloid-induced neuronal degeneration and apoptosis, as evidenced by decreased cleaved caspase-3 expression and preservation of axonal integrity. …”

Efficacy of Lebanese Cannabis Oil Extract in the Treatment of Folic Acid-Induced Renal Fibrosis in Rats by Bylan, Diana

“…Kidney disease is a main contributor to mortality and morbidity worldwide. …”
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Systemic Inflammation May Induce Cardiac Injury in COVID-19 Patients Including Children and Adolescents Without Underlying Cardiovascular Diseases: A Systematic Review by Arwa Saed Aldien (17302849)

“…Increasing amounts of evidence suggest that a system-wide inflammatory response and a cytokine storm mediated type syndrome plays a crucial role in disease progression. This systematic review investigates the possible role of hyperinflammation in inducing cardiac injury as one of the severe complications of COVID-19. …”

Therapeutic Effect of Lebanese Cannabis Oil Extract in the Management of Sodium Orthovanadate-Induced Nephrotoxicity in Rats by Habchy, Chistabel

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Investigation of the Effect of Exendin-4 on Oleic Acid-Induced Steatosis in HepG2 Cells Using Fourier Transform Infrared Spectroscopy by Olfa Khalifa (10914452)

“…FTIR and chemometric analyses revealed that Ex-4 significantly reduces OA-induced lipid accumulation, and Ex-4 also restored the lipid and protein biochemical alterations caused by lipotoxicity-induced oxidative stress. …”

Cold responses and hormonal echoes: a comprehensive view of Raynaud’s vascular dysfunction by Manal Fardoun (16328847)

“…Interestingly, Raynaud’s phenomenon incidence is significantly higher in premenopausal females compared to age-matched males, highlighting a role of the female hormone, estrogen, in Raynaud’s phenomenon pathogenesis. …”

Cadmium-induced endothelial dysfunction mediated by asymmetric dimethylarginine by Hamda A. Al-Naemi (14151675)

Local arterial vasoconstriction induced by octreotide in patients with cirrhosis by Chatila, Rajaa

“…Octreotide probably has a facilitating effect over vasoconstrictors increased in chronic liver diseases…”
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Metabolic Profiling of Exercise-induced Autophagy-dependent Metabolites in Mouse Plasma by Fadel, Joanna

“…This study demonstrates the significant changes in the plasma metabolome induced by exercise, which are partially mediated by autophagy. …”
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Kounis syndrome: acute myocardial injury triggered by ant bite-induced anaphylaxis by Omar Altermanini (22391776)

“…Coronary angiography and cardiac MRI were unremarkable, ruling out significant coronary artery disease. The patient was diagnosed with Kounis syndrome and discharged with an EpiPen and instructions for anaphylaxis management. …”

Cardioprotective effect of Sanguisorba minor against isoprenaline-induced myocardial infarction in rats by Azar Hosseini (33501)

“…Histopathological studies of the cardiac tissue showed isoprenaline-induced injury that was significantly attenuated by the extract.…”

Sleeping habits during COVID-19 induced confinement: A study from Jordan by Mahmoud A. Alomari (14780446)

“…In conclusion, changes in sleep quality during COVID-19-induced confinement were reported. Intervention programs and strategies are warranted to further improve sleep during the current and future disease-induced confinement.…”

Plant Leaf Disease Detection Using Ensemble Learning and Explainable AI by Ammar Oad (21324182)

“…Much like human health, plants face susceptibility to diseases induced by viruses and bacteria, necessitating careful attention to plant care and disease identification. …”

Burden and disease pathogenesis of influenza and other respiratory viruses in diabetic patients by Swapna Thomas (17337925)

“…Vaccinating diabetic patients against influenza would significantly reduce hospitalization due to disease severity. …”

Mitochondrial dysfunction: A notable contributor to the progression of Alzheimer's and Parkinson's disease by Abolaji Samson Olagunju (16855185)

“…They are involved in maintaining optimal cell functioning and ensuring guidance against possible DNA damage, which could lead to mutations and the onset of diseases. Conversely, system perturbations, which could be due to environmental factors or senescence, induce changes in the physiological balance and result in mitochondrial function impairment. …”

IL-1 stimulates ceramide accumulation without inducing apoptosis in intestinal epithelial cells by Homaidan, Fadia R.

“…Background: In inflammatory bowel disease (IBD), cytokine levels (such as interleukin-1 (IL-1)) are elevated. …”
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