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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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The impact of strategy diffusion on organisational performance of project-based organisations
Published 2021“…This study used a quantitative method to investigate the influence of strategy diffusion on organisational performance within project-based organisations, where significant positive influences on the relationships were found between the required research variables. …”
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A Social Constructionist Perspective on the Diffusion of Innovative Fiscal Responsibility Legislation
Published 2013“…The relative durability of myths compared to fads lend an unpredictability to the diffusion process, the potential limits of which are shaped by cultural and institutional factors that influence the receptiveness of governments to such norm-based approaches to fiscal discipline.…”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Benefit of consolidative radiation therapy in patients with diffuse large B-cell lymphoma treated with R-CHOP chemotherapy
Published 2010“…Purpose The current standard therapy for patients with diffuse large B-cell lymphoma (DLBCL) is rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP). …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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Analysing Factors Influencing AI Implementation Effectiveness in the UAE Public Sector
Published 2023“…This research examines factors influencing AI implementation effectiveness in the public sector. …”
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Project manager perceptions factors influencing the delivery of successful innovation in construction projects
Published 2018“…The main findings show that there is an influence of project manager perceptions factors on delivering successful innovation at a construction project level with evidence that his leadership, capabilities/competences, personality traits, and skills (non-engineering skills) are relatively important for the significance influence. …”
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Adsorption and diffusion behavior of pure H<sub>2</sub>, and H<sub>2</sub>/CO<sub>2</sub>, H<sub>2</sub>/CH<sub>4</sub> mixtures in sandstone-rich clay shale reservoirs: Insights f...
Published 2025“…In contrast, the Q<sup>2</sup> silica morphology (ionized with Na and OH) showed reduced interfacial density and adsorption, enabling higher H<sub>2</sub> diffusivity. CO<sub>2</sub> had the strongest surface affinity and served as a more effective diffusion barrier than CH<sub>4</sub> with 25 % cushion gas significantly reduced H<sub>2</sub> mobility. …”
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Drivers of AI Adoption for Project Risk Management in the UAE’s Oil and Gas Industry
Published 2025“…The findings revealed that compatibility significantly influenced AI adoption intentions, while other factors, such as innovation culture, leadership support, and complexity, were not supported. …”
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Drivers of AI Adoption for Project Risk Management in the UAE’s Oil and Gas Industry
Published 2025“…The findings revealed that compatibility significantly influenced AI adoption intentions, while other factors, such as innovation culture, leadership support, and complexity, were not supported. …”
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Alterations in blood Lipoprotein & Apolipoprotein B profile induced by moderate acute & chronic alcohol intake in the rat model. (c2002)
Published 2002“…On the other hand, a 3% alcohol consumption (as beer or whisky) maintained for a two months period did not have an effect on fasting plasma TAG concentration while total and LDL cholesterol concentrations showed a significant decrease and HDL cholesterol concentration was moderately increased. …”
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