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Significance of microscopically incomplete resection margin after esophagectomy for esophageal cancer
Published 2016“…There were significant differences between the groups in postoperative histology, with an increase in pathological stage III and TRG 4–5 in the R1 group. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …”
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Accessibility of large events: an empirical study of the Expo 2020 Dubai
Published 2024“…The objective of this paper is to contribute to understanding the accessibility of large events in an increasingly technology-dependent industry. …”
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Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications
Published 2025“…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Anti-xa guided enoxaparin thromboprophylaxis is associated with less thromboembolism than fixed dose dalteparin in trauma patients admitted to intensive care
Published 2025“…Low-molecular-weight heparin (LMWH) is recommended for VTE prophylaxis (VTEp). We investigated whether switching from fixed-dose dalteparin to anti-Xa-guided enoxaparin prophylaxis reduces VTE without increasing the risk of bleeding among hospitalized trauma patients.…”
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A GRASP Approach for Solving Large-Scale Electric Bus Scheduling Problems
Published 2021“…The results also show that high speed chargers have a more significant impact than an increase in battery sizes of the EBs.…”
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Aerosol Optical Thickness over Large Urban Environments of the Arabian Peninsula—Speciation, Variability, and Distributions
Published 2019“…Over the past decade, the mean annual aerosol optical thickness (AOT) values were in the range of 0.3–0.5, which is attributed to both mineral dust (60–70%) and anthropogenic activities (20–30%). An increase in AOT values between 2005 and 2009 is attributed to increased dust generation from the Sahel region in Northern Africa, and the Fertile Crescent (Syria, Iraq, Jordan) due to an extended dry period. …”
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Ethnic-specific association of amylase gene copy number with adiposity traits in a large Middle Eastern biobank
Published 2021“…Indeed, lower AMY1 CN was associated with increased total and trunk fat percentages in Arabs (P < 4.60 × 10−3) but not in Persians. …”
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When Should a Brain MRI Be Performed in Children with New-Onset Seizures? Results of a Large Prospective Trial
Published 2021“…Univariate analysis showed a significant increase in the frequency of epileptogenic lesions with decreasing age, the presence of developmental delay, and the number and types of seizures at presentation. …”
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Benthic development on large-scale engineered reefs: a comparison of communities among breakwaters of different age and natural reefs
Published 2011“…Breakwaters represent large-scale engineered artificial reefs that can develop diverse and abundant communities and are likely to play an increasing role in marine ecosystems as human populations grow in coastal urban areas. …”
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