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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Reduced graphene aerogels as energy efficient selective oil sorbents
Published 2022“…The presence of H<sub>2</sub> significantly decreased the oxygen-containing functional groups in graphene aerogel. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Perceptions of Science Teachers Regarding Instruction that Increase High School Students' Motivation to Learn Science in Al Ain City
Published 2023“…This study recommended that other studies be conducted on science instruction that increases students’ motivation to learn science using a broader sample to include other schools and other educational stages and with a larger sample size of teachers. …”
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Two-surgeon technique of parenchymal transection contributes to reduced transfusion rate in patients undergoing major hepatectomy
Published 2010“…Although transfusion rates can be reduced to almost 0 in uncomplicated hepatectomies, the blood transfusion rates associated with liver resection remain significant at tertiary referral centers, such as ours. …”
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Reversal of memory and neuropsychiatric symptoms and reduced tau pathology by selenium in 3xTg-AD mice
Published 2018“…Chronic sodium selenate treatment efficiently reversed hippocampal-dependent learning and memory impairments, and behavior- and neuropsychiatric-like symptoms in old female 3xTg-AD mice. Selenium significantly decreased the number of aggregated tau-positive neurons and astrogliosis, without globally affecting amyloid plaques, in the hippocampus of 3xTg-AD mice. …”
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An imageable retinoid acid derivative to detect human cancer xenografts and study therapeutic dosing to reduce its toxicity
Published 2010“…In addition, retinoic acid can reverse premalignancy, significantly decrease second primary tumors and provide a treatment benefit in head and neck, lung, esophagus, colon and bladder cancer. …”
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Ecotoxicological Assessment of Thermally- and Hydrogen-Reduced Graphene Oxide/TiO<sub>2</sub> Photocatalytic Nanocomposites Using the Zebrafish Embryo Model
Published 2019“…However, both nanocomposites should be used with caution at concentration higher than the NOEC (400 mg/L), in particular RGOTi, which significantly (i) caused pericardial and yolk sac edema; (ii) decreased the hatching rate, locomotion, and hematopoietic activities; and (iii) affected the heart rate. …”
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Research on the potential of photovoltaic technologies in reducing energy consumption in an urban mixed use residential community. A Case study for net zero energy community in Dub...
Published 2018“…Therefore, the key challenge is to reduce the consumption of fossil fuels which decreases the production of greenhouse gases such as CO2 and CH4 by using renewable energy technologies to provide clean carbon free energy that can combat future energy security challenges. …”
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A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase
Published 2015“…The permeability effect of 12-HETE was significantly reduced in NOX2<sup>−/−</sup> mice compared with the WT mice. …”
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Optimum sizing of steam turbines for concentrated solar power plants
Published 2012“…For capacity sizes of 10kWe up to 50MWe, the steam turbine efficiency increases and the steam turbine expected specific capital cost of the power block decreases at a high rate, whereas for larger sizes they remain almost constant. …”
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Determinants of Domestic Workers' Employment
Published 2012“…Controlling for household, household head, dwelling, and regional characteristics, we find that the probability of hiring a domestic worker is significantly higher for larger households, female headed households, larger dwellings, and increases with aggregate household consumption. …”
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Habitat Complexity Influences the Microhabitat Choices of Desert Beetles
Published 2011“…The model predicts that prey survivorship is maximized at intermediate Sp/Py values, such that prey can fit through the spaces in a habitat, but their larger predators cannot. The model also predicts that prey survivorship increases with increasing cover (Ct/At), which interferes with predators' ability to detect prey. …”
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Symptoms of depression and anxiety in anorexia nervosa
Published 2014“…It has been hypothesised that reduced availability of tryptophan (TRP) could reduce serotonin activity and thus trigger these comorbid symptoms. …”
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Competition, regulation, and systemic risk in dual banking systems
Published 2024“…Additionally, we find that larger banks are more vulnerable to systemic risk, and the lack of competition worsens this vulnerability. …”
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The Protective Effects of Daucus carota L. ssp. carota and Cannabis sativa L. Extracts against Cisplatin Induced Nephrotoxicity in Animal Models
Published 2021“…All used doses of COE showed significant decrease in serum urea; however, a significant decrease in serum creatinine was observed only at 20 mg/kg COE. …”
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Competition, regulation, and systemic risk in dual banking systems
Published 2024“…Additionally, we find that larger banks are more vulnerable to systemic risk, and the lack of competition worsens this vulnerability. …”