Ziziphus nummularia attenuates the malignant phenotype of human pancreatic cancer cells: Role of ros by Mesmar, J.

“…In addition, ZNE significantly decreased the migratory and invasive capacity of Capan-2 with a concomitant downregulation of integrin α2 and increased cell–cell aggregation. …”
Get full text
Get full text
Get full text

Nickel Toxicity Interferes with NO3−/NH4+ Uptake and Nitrogen Metabolic Enzyme Activity in Rice (Oryza sativa L.) by Rizwan, Muhammad

“…A Ni concentration of 200 µM significantly decreased the NO3− concentration in rice leaves, as well as the activities of nitrate reductase (NR), nitrite reductase (NiR), glutamine synthetase (GS), and glutamate synthetase (GOGAT), respectively, when compared to the control. …”
Get full text
Get full text
Get full text

Nitric Oxide Releasing Hydrogel Nanoparticles Decreases Epithelial Cell Injuries Associated With Airway Reopening by Shurbaji, Samar Haroon

Get full text
Get full text

Nitric Oxide Releasing Hydrogel Nanoparticles Decreases Epithelial Cell Injuries Associated With Airway Reopening. by Shurbaji, Samar

Get full text
Get full text

NADPH-derived ROS generation drives fibrosis and endothelial-to-mesenchymal transition in systemic sclerosis: Potential cross talk with circulating miRNAs by Posadino, Anna Maria

“…Sera from SSc patients showed significant changes in the expression of a set of fibrosis/EndMT-associated microRNAs (miRNA), including miR-21, miR-92a, miR-24, miR-27b, miR-125b, miR-29c, and miR-181b, which resulted significantly upregulated as compared to healthy donors sera. …”
Get full text
Get full text
Get full text

Sanguinarine suppresses growth and induces apoptosis in childhood acute lymphoblastic leukemia by Kuttikrishnan S.

“…Sang mediates its anti-cancer activity by generation of reactive oxygen species (ROS) due to depletion of glutathione level in leukemic cell lines. …”
Get full text
Get full text

Signaling pathways activated by PACAP in MCF-7 breast cancer cells by Zibara, Kazem

“…Furthermore, PACAP induced ROS through H₂O₂ production whereas pretreatment with NAC inhibitor decreased AKT and ERK phosphorylation, but not p38. …”
Get full text
Get full text

Ethanolic extract of Origanum syriacum L. leaves exhibits potent anti-breast cancer potential and robust antioxidant properties by Mesmar, Joelle

“…Non-cytotoxic concentrations of OSEE attenuated cell proliferation and induced G0/G1 cell cycle arrest, which was associated with phosphorylation of p38 MAPK, an increase in the levels of tumor suppressor protein p21, and a decrease of proliferation marker protein Ki67. Additionally, only higher concentrations of OSEE were able to attenuate inhibition of proliferation induced by the ROS scavenger N-acetyl cysteine (NAC), indicating that the anti-proliferative effects of OSEE could be ROS-dependent. …”
Get full text
Get full text
Get full text

ASSOCIATION BETWEEN INSULIN RESISTANCE AND NITRIC OXIDE IN HUMAN RETINAL MICROVASCULAR ENDOTHELIAL CELLS IN VITRO by Bushra, Sumbul

“…This study demonstrated that Hyperglycemia causes an increase in ROS/oxidative stress and apoptosis, while insulin promotes a significant decrease in ROS and apoptosis, eNOS mediated NO production increases with hyperglycemia but remarkably reduced with insulin treatment after 1hour, 2 hours and 4 hours. …”
Get full text

Association between Insulin and Nitric Oxide in Human Retinal Microvascular Endothelial Cells in vitro by Rizk, Nasser Moustafa

“…This study demonstrated that hyperglycemia causes an increase in ROS/oxidative stress and apoptosis, while insulin promotes a significant decrease in ROS and apoptosis. eNOS mediated NO production increases with hyperglycemia but remarkably decreases with insulin treatment after 1 hour, 2 hours and 4 hours. …”
Get full text
Get full text

Individual and Synergic Effects of Phosphorus and Gibberellic Acid on Organic Acids Exudation Pattern, Ultra-Structure of Chloroplast and Stress Response Gene Expression in Cu-Stre... by Alatawi, Aishah

“…Results revealed that C. capsularis tolerated up to 200 mg kg−1 Cu concentration without a significant (P < 0.05) decrease in biomass, plant height and root length but further increase in Cu concentration from 400 mg kg−1 exhibited a significant reduction in plant height, root length, stem fresh weight, stem dry weight, plant fresh weight and plant dry weight. …”
Get full text
Get full text
Get full text

Factors Affecting Waterpipe Tobacco Smoking among University Students in Qatar. by Al-Jayyousi, Ghadir Fakhri

“…Participants were selected through stratified random sampling of students in the largest national university in Qatar. Data were collected anonymously using an online questionnaire. …”
Get full text
Get full text

Docosahexaenoic Acid Counteracts the Hypoxic-Induced Inflammatory and Metabolic Alterations in 3T3-L1 Adipocytes by Younes, Noura B.

“…In addition, DHA-treatment of hypoxic cells caused a significant reduction in the apoptosis rate and ROS production with decreased lipid peroxidation. …”
Get full text
Get full text
Get full text

Effect of hypoxia on metabolic markers and gene expression HIF-1 α in adipocytes by Younes, Noura B.

“…Results: Under hypoxia conditions, DHA treatment resulted in significant changes in all critical parameters of adipocyte biology including HIF-1α RNA expression (decreased by 50%), decreased lactate and glycerol release (66% and 25% respectively), and reactive oxygen species (ROS) production (decreased by 15%), while glucose uptake was decreased by 25% accompnied by decreased secretion of pro-inflammatory markers (Interleukin 6 IL-6, 31% reduction) , macrophage chemoattractant protein 1 MCP-1 (38% reduction) and leptin (14% reduction), and increased adiponectin secretion (by 45%). …”
Get full text

Heart Rate Variability Analysis Reveals a Non-monotonic Relationship between Humanin Concentration and Cardiac Autonomic Regulation by Feng, Samuel

“…Mitochondrial ATP production is the main source of reactive oxygen species (ROS) and hence the regulation of ROS becomes an important issue in maintaining optimal ANS functionality. …”
Get full text
Get full text

12/15-Lipoxygenase-Derived Lipid Metabolites Induce Retinal Endothelial Cell Barrier Dysfunction: Contribution of NADPH Oxidase by Othman, Amira

“…Treatment of diabetic mice with baicalein significantly decreased retinal HETE, ICAM-1, VCAM-1, IL-6, ROS generation, and NOX2 expression. …”
Get full text
Get full text

Phase change materials for thermal energy storage applications in greenhouses: A review by Nishad S.

“…Greenhouses represent one of the largest energy-demanding sectors, requiring energy for indoor environment control for plant growth and crop yield. …”
Get full text
Get full text
Get full text

Oxidative stress-induced Akt downregulation mediates green tea toxicity towards prostate cancer cells by Posadino, Anna Maria

“…Treatment of PC3 cells with 30 and 100μg/ml PE significantly decreased cell viability and proliferation. …”
Get full text
Get full text
Get full text

Effect of sintering temperature of NBT–6BT lead-free ceramics on the structural, ferroelectric and piezoelectric properties by Slimani, Ahmed

“…However, the density decreased significantly with increasing the calcination temperature above 850 °C due to the secondary phase formation. …”
Get full text

Impact of the fear of Covid-19 infection on intent to breastfeed; a cross sectional survey of a perinatal population in Qatar by Reagu, Shuja Mohd

“…Conclusions: The rates of Obsessive-compulsive symptoms were increased and the rates of intent to breastfeed were decreased when compared with pre pandemic rates. The obsessive-compulsive symptoms and the intent to not breastfeed were significantly associated with fear of infection to the new-born. …”
Get full text
Get full text