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Showing 1 - 20 results of 84 for search '(( significantly linked decrease ) OR ( ((significant increases) OR (significant decrease)) ros ))', query time: 0.10s Refine Results
  1. 1
    Aorta deformation linked to heart disease

    Aorta deformation linked to heart disease by Nature Research (16552612)

    Published 2015
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  2. 2
    Selective induction of apoptosis in T-cell acute lymphoblastic leukemia by pristimerin through dual PI3K/AKT pathway inhibition and ROS generation

    Selective induction of apoptosis in T-cell acute lymphoblastic leukemia by pristimerin through dual PI3K/AKT pathway inhibition and ROS generation by Shilpa Kuttikrishnan (3520079)

    Published 2025
    “…In this study, we demonstrate that Prist effectively inhibits the proliferation of T-ALL cell lines (Jurkat and Molt 4) by inducing G0/G1 cell cycle arrest and triggering intrinsic and extrinsic caspase-dependent apoptosis. Prist significantly increases reactive oxygen species (ROS) levels and depletes glutathione (GSH), leading to mitochondrial dysfunction and cytochrome c release. …”
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  3. 3
    ROS-Mediated Autophagic Death in Glioblastoma Cells Upon Treatment by Human Recombinant Arginase I (Co)- PEG5000 [HuArgI (Co)-PEG5000]

    ROS-Mediated Autophagic Death in Glioblastoma Cells Upon Treatment by Human Recombinant Arginase I (Co)- PEG5000 [HuArgI (Co)-PEG5000] by Abdel Khalek, Maya

    Published 2021
    “…Addition of N-acetyl-cysteine (NAC); being a reactive oxygen species (ROS) scavenger, led to a significant decrease in the cytotoxicity of arginine deprivation to U251 and A172 cells, indicating that ROS generation reversed the cytotoxicity of arginine deprivation to GBM cells. …”
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  4. 4
    Curcumin Induces Apoptotic Cell Death via Inhibition of PI3-Kinase/AKT Pathway in B-Precursor Acute Lymphoblastic Leukemia

    Curcumin Induces Apoptotic Cell Death via Inhibition of PI3-Kinase/AKT Pathway in B-Precursor Acute Lymphoblastic Leukemia by Shilpa Kuttikrishnan (3520079)

    Published 2019
    “…<p dir="ltr">Acute lymphoblastic leukemia (ALL) is a significant cancer of children resulting from the clonal proliferation of lymphoid precursors with arrested maturation. …”
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  5. 5
    Dynamic Analysis of Flexible Mechanisms with Clearance

    Dynamic Analysis of Flexible Mechanisms with Clearance by Ahmedalbashir, Mona Abdullah Hassan

    Published 2016
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  6. 6
    Resveratrol Inhibits Oxidative Stress and Prevents Mitochondrial Damage Induced by Zinc Oxide Nanoparticles in Zebrafish (<em>Danio rerio</em>)

    Resveratrol Inhibits Oxidative Stress and Prevents Mitochondrial Damage Induced by Zinc Oxide Nanoparticles in Zebrafish (<em>Danio rerio</em>) by Roberta Giordo (299595)

    Published 2020
    “…Mechanistically, we further showed that resveratrol inhibits ROS increase, prevents mitochondrial membrane potential dysfunction, and counteracts cell apoptosis/necrosis elicited by ZnO NP. …”
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  7. 7
    A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase

    A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase by Ahmed S. Ibrahim (10049522)

    Published 2015
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  8. 8
    Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway

    Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway by Kirti.S. Prabhu (17191231)

    Published 2021
    “…In addition, we established the antitumor effects of SNG through reactive oxygen species (ROS) production, as inhibiting ROS production prevented the apoptosis-inducing potential of SNG. …”
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  9. 9
    An investigation into links between UAE STI Policy and the Federal Universities STEM Majors’ Enrolments, Graduates and Research Development: an evidence-based exploration of the impact of UAE STI policy

    An investigation into links between UAE STI Policy and the Federal Universities STEM Majors’ Enrolments, Graduates and Research Development: an evidence-based exploration of the im... by Khreibi, Rima Abou

    Published 2020
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  10. 10
    Bortezomib exerts its anti-cancer activity through the regulation of Skp2/p53 axis in non-melanoma skin cancer cells and C. elegans

    Bortezomib exerts its anti-cancer activity through the regulation of Skp2/p53 axis in non-melanoma skin cancer cells and C. elegans by Kirti S. Prabhu (4246144)

    Published 2024
    “…We also found that BTZ exerted its antitumor effects by generating reactive oxygen species (ROS), as blocking ROS production significantly reduced BTZ-induced apoptotic cell death. …”
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  11. 11
    Carotenoids in Cancer Apoptosis—The Road from Bench to Bedside and Back

    Carotenoids in Cancer Apoptosis—The Road from Bench to Bedside and Back by Lenka Koklesova (18102994)

    Published 2020
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  12. 12
    Cytotoxicity of Arginine Deprivation to AML Cells is Mediated by Autophagy

    Cytotoxicity of Arginine Deprivation to AML Cells is Mediated by Autophagy by Taki, Fatima

    Published 2020
    “…Inhibition of autophagy, using chloroquine, led to a significant decrease in cell cytotoxicity evident at 48 hours and up to 120 hours. …”
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  13. 13
    Arginine Deprivation in AML Cells Induces Ferroptosis, a Type of Autophagy-Mediated Cell Death

    Arginine Deprivation in AML Cells Induces Ferroptosis, a Type of Autophagy-Mediated Cell Death by Tohme, Sara

    Published 2023
    “…Scavenging ROS using NAC significantly decreases cell death but has minimal effect on autophagy activation, suggesting that the accumulation of ROS is downstream of autophagy activation but upstream of cell death. …”
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  14. 14
    Heart Rate Variability Analysis Reveals a Non-monotonic Relationship between Humanin Concentration and Cardiac Autonomic Regulation

    Heart Rate Variability Analysis Reveals a Non-monotonic Relationship between Humanin Concentration and Cardiac Autonomic Regulation by Feng, Samuel

    Published 2022
    “…A mitohormetic type of relationship was observed with HRV features increasing and then decreasing with increasing HN concentration. …”
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  15. 15
    Anticancer Effects of Lebanese Cannabis Oil Against in vivo and in vitro Models of Squamous Cell Carcinoma

    Anticancer Effects of Lebanese Cannabis Oil Against in vivo and in vitro Models of Squamous Cell Carcinoma by Azar Atallah, Shirine

    Published 2023
    “…Reactive oxygen species (ROS) detection assay did not show a significant involvement of oxidative stress in the cytotoxicity of COE. …”
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  16. 16
    Drug-free phototherapy of superficial tumors

    Drug-free phototherapy of superficial tumors by Mehanna, Stephanie

    Published 2021
    “…When tested on a DMBA/TPA skin carcinogenesis model, a 90-min exposure to white light thrice weekly resulted in a significant decrease in tumor volumes/incidence compared to control and cisplatin groups, and restored normal morphological features, as confirmed by histopathology. …”
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  17. 17
    Renal Function Decline in Recipients and Donors of Kidney Grafts

    Renal Function Decline in Recipients and Donors of Kidney Grafts by Bahous, Sola Aoun

    Published 2015
    “…Background/Aims: Renal function decreases over time as a result of reduction in the number of functioning nephrons with age. …”
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  18. 18
    In Vitro and In Vivo Effects of Lebanese Cannabis Oil Against Acute Myeloid Leukemia (AML)

    In Vitro and In Vivo Effects of Lebanese Cannabis Oil Against Acute Myeloid Leukemia (AML) by Lteif, Anthony

    Published 2023
    “…Western blots analysis further demonstrated that COE triggered a caspase-dependent apoptosis via the extrinsic and intrinsic pathways. In addition, COE significantly inhibited the MAPK pathway. A significant inhibition of ROS production was also observed with COE treatment. …”
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  19. 19
    Investigating vulnerability for developing eating disorders in a multi-confessional lebanese sample

    Investigating vulnerability for developing eating disorders in a multi-confessional lebanese sample by Khazen, Georges

    Published 2015
    “…Being Christian was found to significantly decrease the vulnerability to developing an ED. …”
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  20. 20
    Host Genetic Variants Potentially Associated With SARS-CoV-2: A Multi-Population Analysis

    Host Genetic Variants Potentially Associated With SARS-CoV-2: A Multi-Population Analysis by Maria K. Smatti (4675852)

    Published 2020
    “…Analysis of Qatari genomes revealed significantly lower AF of risk variants linked to SARS-CoV-1 severity (CCL2, MBL, CCL5, AHSG, and IL4) compared to that of 1000Genome and/or the EAS population (up to 25-fold change). …”
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