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Arginine Deprivation in AML Cells Induces Ferroptosis, a Type of Autophagy-Mediated Cell Death
Published 2023“…In this study, we showed for the first time that arginine deprivation using a recombinant human arginase induces ferroptosis, an autophagy-mediated type of cell death in AML cells. Acute Myeloid Leukemia (AML) poses significant challenges due to its unfavorable prognosis and limited treatment options, particularly in elderly patients. …”
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The protective effects of conditioned media from human mesenchymal stem cells against Methylglyoxal-mediated injury of cultured endothelial cells
Published 2023“…Our findings showed a significant protective effect of MSCs-CM (50%) on MGO-mediated cell death and caspases 3/7 activation in endothelial cells.…”
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School children growth monitoring program in the state of Qatar: Observations from two survey rounds in 2016–17 and 2019–20
Published 2023“…</p><h3>Results</h3><p dir="ltr">Overall, the proportion of overweight and obese category of students increased from 44% in 2016–17 to 49.3% in 2019–20 with a decrease in the proportion of students in normal BMI‐z‐score category (from 48.8% to 47.8%) and severe thinness and thinness category (from 7.3% to 3%) between two rounds of growth monitoring survey. …”
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Oxygen targets following cardiac arrest: A meta-analysis of randomized controlled trials
Published 2023“…</p> <h3>Conclusions</h3> <p>Conservative oxygen therapy did not decrease mortality, improve neurologic recovery, or decrease ICU LOS as compared to a liberal oxygen regimen. …”
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Application of hierarchical oligonucleotide primer extension (HOPE) to assess relative abundances of ammonia- and nitrite-oxidizing bacteria
Published 2017“…There was a corresponding significant decrease in the relative abundance of NOB, specifically Nitrospira and those affiliated to comammox, during the shock loading. …”
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Rescue cerclage
Published 2006“…Outcomes assessed are prolongation of pregnancy in weeks, mean gestational age at delivery, proportion of women reaching 28, 32, and 34 weeks, neonatal survival rate, and mean birth weight. …”
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The Impact of Different Urban Configurations on Outdoor Thermal Comfort: A Case Study of the Military Camps in Abu Dhabi, UAE
Published 2016“…One main conclusion is that bioclimatic urban design can be used to achieve a significant improvement of outdoor thermal comfort. …”
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DNAJB3/HSP-40 cochaperone improves insulin signaling and enhances glucose uptake in vitro through JNK repression
Published 2015“…<p dir="ltr">Heat shock response (HSR) is an essential host-defense mechanism that is dysregulated in obesity-induced insulin resistance and type 2 diabetes (T2D). …”
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The Grid Iron Patterns & Detached Villas as the Main Drivers of Sharjah City’s Urban Sprawl
Published 2021“…This rapid growth coincided with two phenomena worthy of attention, the first being the conjunction of this growth with the significant decline in residential density, and the second with the phenomenon of the increase in the proportion of non-durable residential lands, which reached 49% (DTPS, 1998) of the total land allocated to citizens. …”
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Effect of clinical hyperthyroidism and hypothyroidism on patent diabetes. 59 cases
Published 1983“…This incidence was significantly higher than the calculated probability of the two diseases occurring by chance in the same patient. …”
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Accelerating Care: Enhancing Patient Satisfaction through a Quality Initiative in the Obstetrics and Gynaecology Emergency Department at Al Wakra Hospital, Qatar
Published 2023“…</p><h3>Results</h3><p dir="ltr">The strategies implemented significantly reduced waiting times, enhancing both patient care and operational efficiency. …”
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Exploring Beyond Numeric Weight Loss: The Metabolic Effects of Semaglutide.
Published 2025“…Semaglutide also slowed weight regain and promoted weight loss after failed bariatric surgery. It also significantly reduced ad libitum energy intake, decreased hunger, and increased satiety in multiple trials. …”
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Diffusion tensor imaging with tractography in surgical resection of brainstem cavernous malformations: a systematic review and meta-analysis
Published 2023“…The utilization of preoperative diffusion tensor imaging significantly increased the proportion of improved patients and decreased the proportion of worsened patients. …”
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Relationship Between Hyperglycemia and Infection in Critically Ill Patients
Published 2005“…Intensive insulin therapy minimizes derangements in normal host defense mechanisms and modulates release of inflammatory mediators. …”
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Exploring beyond numeric weight loss: The metabolic effects of semaglutide
Published 2025“…Semaglutide also slowed weight regain and promoted weight loss after failed <u>bariatric surgery.</u> It also significantly reduced ad libitum <u>energy intake</u>, decreased hunger, and increased satiety in multiple trials. …”
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Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss
Published 2018“…Thus, a screening of a cohort of ARHL patients and controls was carried out revealing several variants inSLC7A8, whose role was further investigated by in vitro functional studies. Significant decreases in SLC7A8 transport activity was detected for patient’s variants (p.Val302Ile, p.Arg418His, p.Thr402Met and p.Val460Glu) further supporting a causative role for SLC7A8 in ARHL. …”
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Dynamics of Neisseria gonorrhoeae transmission among female sex workers and clients: A mathematical modeling study
Published 2024“…In the common low-partner-number HSWNs, a significant proportion of NG incidence occurs among FSWs, with NG prevalence 13 times higher among FSWs than clients, and three times higher among clients than their spouses. …”
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Coping mechanisms among Lebanese first-time college students
Published 2012“…When all those factors were combined together, six variables in addition to gender accounted for significant increments of variance in the level of wellbeing. …”
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