The role of protective genetic variants in modulating epigenetic aging by Yosra Bejaoui (8552574)

The role of protected areas in modulating vegetation response to climatic stressors in hyper-arid ecosystems by Ammar Abulibdeh (15785928)

The Role of Extracellular Vesicles as Modulators of the Tumor Microenvironment, Metastasis and Drug Resistance in Colorectal Cancer by Kodappully S. Siveen (4246150)

“…This transfer influences a number of immune-related pathways leading to activation/differentiation/expression of immune cells and modulation of the tumor microenvironment that plays a significant role in CRC progression, metastasis, and drug resistance. …”

Reduction of laboratory utilization in the intensive care unit by Diab, Khalil

“…Conclusion: A simple technique of resident, nursing, and ancillary staff education, combined with alterations in order sets using electronic medical records, can lead to a sustained reduction in laboratory test utilization over time and to significant cost savings without affecting patient safety.…”
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L1-CAM knock-down radiosensitizes neuroblastoma IMR-32 cells by simultaneously decreasing MycN, but increasing PTEN protein expression by Rached, Johnny

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Differing endometrial expression of calcium modulating transient receptor potential channels by Maryam Ghavideldarestani (11862563)

“…TRPC 1–4 and 6 expression in the bovine reproductive tract has been reported; these receptors exhibit hormone modulation [2] and calcium dysregulation can lead to menstrual disturbances [3], suggesting that TRPC receptors may modulate calcium in the human endometrium and affect implantation and fertility.…”

A comparison of peer, teacher and self-feedback on the reduction of language errors in student essays by Diab, Nuwar Mawlawi

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Parameter identification of PV solar cells and modules using bio dynamics grasshopper optimization algorithm by Mostafa Jabari (21841727)

“…<p dir="ltr">The escalating global population and energy demands underscore the critical role of renewable energy sources, particularly solar power, in mitigating environmental degradation caused by traditional fossil fuels. …”

Nurse-Led System-wide Unit-based Hospital Acquired Pressure Injury (HAPI) Reduction Project by Mariam Al-Mutawa (18505317)

“…Medical devices contribute to approximately 50% of these total HAPI. HAPI is a significant patient safety issue in hospitalized patients and can lead to increased healthcare costs and a decreased quality of life for patients . …”

Theoretical insight into effect of cation–anion pairs on CO₂ reduction on bismuth electrocatalysts by Sun Hee Yoon (7179263)

“…The adsorption energy (Eads) and work function (Wf) of the anions increases with decreasing anion size (i.e., Cl⁻ > Br⁻ > I⁻). …”

A positive change in energy balance modulates TrkB expression in the hypothalamus and nodose ganglia of rats by Zeeni, Nadine

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Chronic reduction of store operated Ca²⁺ entry is viable therapeutically but is associated with cardiovascular complications by Fang Yu (156838)

“…</p> <h2>Key points</h2> <ul> <li>A floxed stromal interaction molecule 1 (STIM1) hypomorph mouse model was generated with significant reduction in Ca²⁺ influx through store-operated Ca²⁺ entry (SOCE), resulting in defective nuclear translocation of nuclear factor of activated T cells, cytokine production and inflammatory response. …”

Proteomic insight towards key modulating proteins regulated by the aryl hydrocarbon receptor involved in ovarian carcinogenesis and chemoresistance by Lubna Therachiyil (4246156)

“…We have previously reported that exposure of OC cells to TCDD, an AhR activator, significantly modulated the expression of several genes that play roles in stemness and chemoresistance. …”

Pristimerin mediated anticancer effects and sensitization of human skin cancer cells through modulation of MAPK signaling pathways by Maha Al-Tamimi (17280550)

Exosome nanovesicles as potential biomarkers and immune checkpoint signaling modulators in lung cancer microenvironment: recent advances and emerging concepts by Naushad Ahmad Khan (6406973)

The role of soluble CD40L in autoimmune diseases by Meryem, Mabrouk

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Exploring the epigenetic landscape: The role of 5-hydroxymethylcytosine in neurodevelopmental disorders by Mohamed Adil Shah Khoodoruth (14589828)

“…In human studies, researchers have linked alterations in 5hmC levels NDDs through studies in individuals with ASD, fragile X syndrome, TET3 deficiency and ID, specifically identifying significant epigenetic modifications in genes such as <i>GAD1, RELN, FMR1 </i>and <i>EN-2</i>, suggesting that dysregulation of 5hmC played a critical role in the pathogenesis of these disorders and highlighted the potential for targeted therapeutic interventions. …”

The effect of microbiome-modulating therapeutics on glucose homeostasis in metabolic syndrome: A systematic review, meta-analysis, and meta-regression of clinical trials by Ridhima Kaul (12485902)

“…</p><h3>Results</h3><p dir="ltr">Data from 21 trial comparisons across 19 studies (n = 911) revealed that, compared to placebo/control, microbiome-modulating therapies were associated with statistically significant changes in fasting <u>plasma glucose</u> (MD: 4.03 mg/dL [95%CI: 6.93; −1.13]; p_effect = 0.006, I² = 89.8 %), and fasting insulin (MD: 2.56 μU/mL [95%CI: 4.28; −0.84]; p_effect = 0.004, I² = 87.9 %), but not insulin resistance or sensitivity indices and <u>HbA1c</u>. …”

Regulatory T Cells in the Tumor Microenvironment and Cancer Progression: Role and Therapeutic Targeting by Belal Chaudhary (19738021)

“…<p dir="ltr">Recent years have seen significant efforts in understanding and modulating the immune response in cancer. …”

Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4 by Olfa Khalifa (10914452)