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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Bacteriuria in pregnancy varies with the ambiance: a retrospective observational study at a tertiary hospital in Doha, Qatar
Published 2023“…<h3>Objectives</h3> <p>To explore the influence of ambient temperature and humidity on significant bacteriuria (SB) and urinary bacterial isolates in pregnant women.…”
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The Influence of Risks on the Performance of E-Business
Published 2016“…The practitioner could get an insight from this study to help prioritize the e-Business risk and assign a correct probability of occurrence as well as the significance of the risk impact. The e-Business risk construct framework with its six e-business modules used in this research present a limitation in the context that not all e-Business firm or practitioners necessarily get involved with the six e-Business modules, which might influence the respondent perception and risk rating. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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The Association between Benefits Realization and Dubai/UAE Infrastructure Development Projects Outcomes
Published 2018“…Findings: The results of the research provided that there is significant positive relationship between Benefits Realization and UAE Infrastructure development project outcomes along with a significant positive relationship between UAE Infrastructure development project outcomes and Identifying Benefits. …”
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Prevalence and clinical significance of antiphospholipid antibodies in patients with coronavirus disease 2019 admitted to intensive care units: a prospective observational study
Published 2022“…Twenty-two patients (37%) were found be antiphospholipid-positive; 21 of them were positive for lupus anticoagulant, whereas one patient was positive for anti-β2-glycoprotein IgG/IgM. …”
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Optical pavement treatments and their impact on speed and lateral position at transition zones: A driving simulator study
Published 2021“…Regarding the variations in drivers' lateral position, the results showed that the proposed pavement markings did not negatively influence drivers' lateral control on the road as the maximum observed standard deviation of lateral position was around 0.065 m. …”
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Source apportionment of PM₂̣ ₅ and PM₁₀ pollutants near an urban roadside site using positive matrix factorization
Published 2024“…Traffic emissions were found to be significant contributors to both PM₂̣ ₅ and PM₁₀ pollution, along with natural sources like sea salt and mineral dust. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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The Role of Social Media Influencers in Electric Vehicle Adoption in the UAE
Published 2025“…The findings indicate that social media influencers exert a direct positive influence on the intention to adopt electric vehicles (β = 0.244, p < 0.01), with confidence in influencers serving as a major mediator of this relationship (β = 0.401, p < 0.001). …”
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The impact of sociocultural influences on the eating attitudes of Lebanese and Cypriot students
Published 2012“…Finally, significant correlations were found between sociocultural influences and eating scores only in the Cypriot sample. …”
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The influence of sociocultural factors on the eating attitudes of Lebanese and Cypriot students
Published 2013“…Finally, sociocultural influences correlated positively with external eating only in the Cypriot sample. …”
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The influence of job security on job performance among Jordanian nurses
Published 2024“…The employee performance score average was (2.68) reflecting a high level of job performance. There is a significant moderate positive relationship between job security and employee performance (r = 0.404, p < 0.01). …”
