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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Iron-related dietary pattern increases the risk of poor cognition
Published 2019“…We aimed to examine the association between iron-related dietary pattern (IDP) and cognitive function in Chinese adults. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Evolutionary algorithms for state justification in sequential automatic test pattern generation
Published 2005“…New approaches are needed to enhance the existing techniques, both to reduce execution time and improve fault coverage. …”
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Meal pattern of male rats maintained on histidine-, leucine-, or tyrosine-supplemented diet.
Published 2007“…Results: Total food intake and feeding rate of the different groups were not affected, although other components of meal pattern were altered. Histidine supplementation reduced diurnal meal size by 42% (p 0.05), whereas that of leucine increased nocturnal meal size by 35% (p 0.05). …”
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Invasive Species as Rivals: Invasive Potential and Distribution Pattern of Xanthium strumarium L.
Published 2022“…<p dir="ltr">Xanthium strumarium L. is a globally successful invasive herb that has had significant negative ecological, economic and social impacts in many world regions. …”
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Pattern of Postoperative Mortality After Esophageal Cancer Resection According to Center Volume
Published 2015“…Background High center procedural volume has been shown to reduce postoperative mortality (POM); however, the cause of POM has been poorly studied previously. …”
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Mortality patterns in older adults with infective endocarditis in the US: A retrospective analysis
Published 2024“…<h3>Background</h3><p dir="ltr">Infective Endocarditis (IE) has become a significant cause of morbidity and mortality over the last two decades. …”
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Association Between Dietary Patterns and Prevalence of Frailty in Community-Dwelling Lebanese Older Adults
Published 2020“…Along with aging, a common geriatric syndrome occurs often, that is frailty. Healthy dietary patterns can contribute to successful aging through reducing risk of frailty. …”
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