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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Student learning in higher education through blogging in the classroom
Published 2019“…It was found that students do perceive higher degrees of learning from using blogs, but the recognised benefits of using blogs is influenced by the students’ attitudes towards the use of technology in teaching and learning, their perceived usefulness of blogs, and the extent to which they have used blogs previously. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …”
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Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications
Published 2025“…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Research Based Pedagogy to Enhance Quality of Learning: A Study Among Selected Higher Education Institutions in the UAE
Published 2024“…Research Based Pedagogy has become the teaching and learning approaches adopted by the universities and higher education institutions in the UAE. Research Based Pedagogy is referred to as a significant concept that would facilitate in creating research culture and to graduate students with high cognitive thinking order. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Examining the Use of Generative Artificial Intelligence in Higher Education and Its Impact on Social Sustainability: An Integrated Model of UTAUT2 and T-EESST
Published 2024“…In this research, the author assesses and evaluates the degree to which the higher education (HE) sector has embraced generative artificial intelligence (GenAI), primarily focusing on the adoption and application of GenAI and its implications for social sustainability. …”
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…While most PDAs close after one 3-day course of either medicine, a repeat course may be necessary before considering surgical ligation for those who remain with hsPDAs. In our practice, we administer one or two courses of ibuprofen followed by a single course of indomethacin if the PDA has not shown closure or decrease in size on the echocardiogram (echo) exam. …”
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IMPACT OF THE UAE NATIONAL SERVICE ON ACADEMIC ACHIEVEMENT AMONG COLLEGE STUDENTS
Published 2021“…The main focus of this study was to investigate the influence of the National Service programme in the UAE among the post-Secondary school Emirati youth on their academic development at higher learning institutions and hence career development in the future. …”
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Occupational Violence at Lebanese Emergency Departments
Published 2011“…Exposure to verbal abuse was associated with serious outcomes including significantly higher levels of occupational burnout and an increased likelihood to quit current job. …”
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The relationship between emotional intelligence and organizational commitment among nurses working in governmental hospitals in Jordan
Published 2023“…Male nurses, widowed nurses, and nurses with higher postgraduate qualifications demonstrated significantly higher levels of emotional intelligence and organizational commitment than female nurses, single nurses, and nurses with undergraduate degrees (p < 0.05).…”
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A Sociodemographic Analysis of the Impact of COVID-19-Related Schools’ Closure on the Diet and Physical Activity of Children and Adolescents in Qatar
Published 2023“…Higher parental educational levels, maternal employment, and having a positive family history of obesity and/or overweight in first-degree relatives were significantly associated with adverse lifestyle changes during schools’ closure.…”
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Optimisation of PV Cleaning Practices: Comparison Between Performance Based and Periodic Based Approaches
Published 2018“…The losses resulting from this can lead to significant losses, especially in a place like Dubai, UAE which meet many of these factors. …”
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