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A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase
Published 2015“…Taken together our data suggest that 12/15-LOX is implicated in DR via a NOX-dependent mechanism.…”
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Effects of different diets on glycemic control among patients with type 2 diabetes: A literature review
Published 2022“…In fact, following alow-fat diet improves glycemic control and decreases HbA1c levels. Studies reported that a low-carbohydrate diet had the greatest effect on improving glycemic control and insulin parameters. …”
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A Review of Pharmacogenetics of Antimalarials and Associated Clinical Implications
Published 2017“…The most critical pharmacogenetic consideration identified was the association of glucose-6-phosphate dehydrogenase deficiency with development of hemolytic anemia and decreased hemoglobin levels in patients treated with primaquine or a combination of chlorproguanil-dapsone-artesunate. …”
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Evaluating the Short-Term Sustainability of Shared E-Scooters: A Usage-Centered Approach
Published 2023“…Recent years have seen a sharp rise in the use of shared electric scooters, which is indicative of a significant change in usage patterns. …”
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Severe vegetation degradation associated with different disturbance types in a poorly managed urban recreation destination in Iran
Published 2021“…Roads and campsites caused the greatest damage, while trails had the smallest negative impact on vegetation. …”
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Effects of covid-19 lockdown on physical activity, sedentary behavior, and satisfaction with life in Qatar: A preliminary study
Published 2021“…In conclusion, COVID-19 confinement decreased PA, increased sitting time, and decreased life satisfaction in Qatar. …”
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The global burden of cancer attributable to risk factors, 2010–19: a systematic analysis for the Global Burden of Disease Study 2019
Published 2022“…From 2010 to 2019, global risk-attributable cancer deaths increased by 20·4% (12·6–28·4) and DALYs by 16·8% (8·8–25·0), with the greatest percentage increase in metabolic risks (34·7% [27·9–42·8] and 33·3% [25·8–42·0]). …”
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Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021
Published 2024“…Gains in future life expectancy were forecasted to be greatest in super-regions with comparatively low life expectancies (such as sub-Saharan Africa) compared with super-regions with higher life expectancies (such as the high-income super-region), leading to a trend towards convergence in life expectancy across locations between now and 2050. …”
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Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021
Published 2024“…Gains in future life expectancy were forecasted to be greatest in super-regions with comparatively low life expectancies (such as sub-Saharan Africa) compared with super-regions with higher life expectancies (such as the high-income super-region), leading to a trend towards convergence in life expectancy across locations between now and 2050. …”
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The Global, Regional, and National Burden of Adult Lip, Oral, and Pharyngeal Cancer in 204 Countries and Territories: A Systematic Analysis for the Global Burden of Disease Study 2...
Published 2023“…From 1990 to 2019, low-middle and low SDI regions consistently showed the highest age-standardized mortality rates due to LOC and OPC, while the high SDI strata exhibited age-standardized incidence rates decreasing for LOC and increasing for OPC. Globally in 2019, smoking had the greatest contribution to risk-attributable OPC deaths for both sexes (55.8% [95% UI, 49.2%-62.0%] of all OPC deaths in male individuals and 17.4% [95% UI, 13.8%-21.2%] of all OPC deaths in female individuals). …”
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Spatially Correlated Time Series and Ecological Niche Analysis of Cutaneous Leishmaniasis in Afghanistan.
Published 2017“…Furthermore, ecological niche modeling was used to study the geographically suitable conditions for cutaneous leishmaniasis using temperature, precipitation and altitude as environmental layers, together with the leishmaniasis presence data. A retrospective analysis of the cutaneous leishmaniasis spatial data in Afghanistan between 2003 and 2009 indicates a steady increase from 2003 to 2007, a small decrease in 2008, and then another increase in 2009. …”
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Removal of toxic pollutants from produced water by phytoremediation: Applications and mechanistic study
Published 2019“…Results showed that except M. sativa, tolerated up to 10% diluted PW with a 30% decrease in length and biomass compared to control treatment, all other plants could not survive. …”
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Removal of toxic pollutants from produced water by phytoremediation: Applications and mechanistic study
Published 2019“…Results showed that except M. sativa, tolerated up to 10% diluted PW with a 30% decrease in length and biomass compared to control treatment, all other plants could not survive. …”
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AMPK Activation Attenuates Albumin-induced Alterations in Renal Tubular Cells In Vitro
Published 2016“…Similarly, the phosphorylation of AKT and P70S6K (a downstream target of mTOR) was increased by more than 1.5-fold in cells subjected to albumin treatment. In addition, albumin treatment caused a dose-dependent reduction in AMPK phosphorylation and about 66% decrease in the expression of autophagy marker LC3-II. …”
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Calmodulin Mutations Associated with Congenital Cardiac Disease Display Novel Biophysical and Biochemical Characteristics
Published 2018“…CaMQ136P protein exhibited a ∼7-fold reduced Ca2+-binding affinity compared to CaMWT, while CaMD132E had a ∼14-fold reduction. …”
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THE ASSOCIATION BETWEEN SOFT DRINK CONSUMPTION AND BONE MINERAL DENSITY AMONG QATARI WOMEN: ANALYSIS OF QATAR BIOBANK DATA
Published 2019“…It is common in older women, as the bone mineral density (BMD) tends to decrease with age, particularly after menopause. Decrease in BMD increases the risk of osteopenia and osteoporosis. …”
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Integrated planning of spare parts and service engineers with partial backlogging
Published 2017“…Moreover, approximation errors decrease as problems get larger. Furthermore, we test how the greedy optimization heuristic performs compared to other discrete search algorithms in terms of total costs and computation times. …”
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Anti-Neoplastic Effects of Annonacin against Renal Cell Carcinoma
Published 2016“…Results: hour annonacin treatment caused a significant and dose-dependent decrease in the viability of CaKi-2 cells, i.e., 42% in 0.5 ?…”
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