Specific Bioactive Compounds from Ginger, Tea, and Apple Prevent Diabetes-Related Cataract Via Inhibition of Aldose Reducatse by Ahmedna, Mohamed

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A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase by Ibrahim, Ahmed S.

“…Taken together our data suggest that 12/15-LOX is implicated in DR via a NOX-dependent mechanism.…”
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AMPK Activation Attenuates Albumin-induced Alterations in Renal Tubular Cells In Vitro by Allouch, Soumaya

“…Similarly, the phosphorylation of AKT and P70S6K (a downstream target of mTOR) was increased by more than 1.5-fold in cells subjected to albumin treatment. In addition, albumin treatment caused a dose-dependent reduction in AMPK phosphorylation and about 66% decrease in the expression of autophagy marker LC3-II. …”
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Calmodulin Mutations Associated with Congenital Cardiac Disease Display Novel Biophysical and Biochemical Characteristics by Nomikos, Michail

“…CaMQ136P protein exhibited a ∼7-fold reduced Ca2+-binding affinity compared to CaMWT, while CaMD132E had a ∼14-fold reduction. …”
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THE ASSOCIATION BETWEEN SOFT DRINK CONSUMPTION AND BONE MINERAL DENSITY AMONG QATARI WOMEN: ANALYSIS OF QATAR BIOBANK DATA by HAMID, AAMNA MOHAMED IDREES ALI

“…It is common in older women, as the bone mineral density (BMD) tends to decrease with age, particularly after menopause. Decrease in BMD increases the risk of osteopenia and osteoporosis. …”
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Integrated planning of spare parts and service engineers with partial backlogging by Rahimi-Ghahroodi, S.

“…Moreover, approximation errors decrease as problems get larger. Furthermore, we test how the greedy optimization heuristic performs compared to other discrete search algorithms in terms of total costs and computation times. …”
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Anti-Neoplastic Effects of Annonacin against Renal Cell Carcinoma by Munusamy, Shankar

“…Results: hour annonacin treatment caused a significant and dose-dependent decrease in the viability of CaKi-2 cells, i.e., 42% in 0.5 ?…”
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Two-stage cultivation of a Nannochloropsis mutant for biodiesel feedstock by Doan, Y.T.T.

“…The biomass yield of the mutant in two-stage cultivation was maintained at a level similar to that of the one-stage photoautotrophic culture, but TFA content was increased by 2.3-fold. The fatty acid profile of MT-I5 also had an increased level of desirable saturated fatty acids (SFA) for use as a biodiesel feedstock, i.e. from 43 to 48�% of TFA, as well as a decreased level of less desirable polyunsaturated fatty acids (PUFA), i.e. from 22 to 7�% of TFA. …”
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Changes in dietary habits and eating behaviors during COVID-19 induced confinement: A study from Jordan by Alomari, Mahmoud A.

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Theoretical insight into effect of cation–anion pairs on CO2 reduction on bismuth electrocatalysts by Sun Hee, Yoon

“…The adsorption energy (Eads) and work function (Wf) of the anions increases with decreasing anion size (i.e., Cl− > Br− > I−). On the other hand, the larger the cation size is, the higher is the Eads (i.e., Li+ < K+ < Cs+) but the lower is the Wf (i.e., Cs+ < K+ < Li+). …”
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Phospholipase C zeta profiles are indicative of optimal sperm parameters and fertilisation success in patients undergoing fertility treatment. by Kashir, Junaid

“…Further focused investigations are required with larger cohorts to examine the full clinical potential of PLCζ.…”
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Solar-driven hydrogen production from a water-splitting cycle based on carbon-TiO2 nano-tubes by Almomani F.

“…This study illustrates the structuring of the TiO2 within carbon nano-tubes to enhance the solar-driven production of hydrogen (S-DPOH) via water splitting. The newly developed Carbon-TiO2 nano-tubes (C-Ti-NTs) aimed at improving the practical applications of TiO2 composites under natural solar irradiation conditions, enhancing the absorption of UV and VIS-light, reduces the required bandgap energy and decreases the chance for photo-induced-charges recombination. …”
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Structure–activity relationship of piperine and its synthetic amide analogs for therapeutic potential to prevent experimentally induced ER stress in vitro by Hammad, Ayat S.

“…Endoplasmic reticulum (ER) is the key organelle involved in protein folding and maturation. Emerging studies implicate the role of ER stress in the development of chronic kidney disease. …”
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Synthesis and Pharmacological Evaluation of Different Piperine Analogs for Therapeutic Potential to Prevent ER Stress by Hammad, Ayat Samir

“…Background: Endoplasmic reticulum (ER) is the chief organelle involved in protein folding and maturation. Emerging studies implicate the role of ER stress in the development of chronic kidney disease (CKD). …”
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Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021 by Natalia V, Bhattacharjee

“…Additionally, the distribution of livebirths across the globe is shifting, with a greater proportion occurring in the lowest-income countries. …”
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Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021 by Natalia V, Bhattacharjee

“…Additionally, the distribution of livebirths across the globe is shifting, with a greater proportion occurring in the lowest-income countries. …”
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