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Soluble Neuropilin-1 Response to Hypoglycemia in Type 2 Diabetes: Increased Risk or Protection in SARS-CoV-2 Infection?
Published 2021“…Slow Off-rate Modified Aptamer (SOMA)-scan plasma protein measurement determined RAS-related proteins: renin (REN), angiotensinogen (AGT), ACE2, soluble NRP1(sNRP1), NRP1 ligands (Vascular endothelial growth factor, VEGF and Class 3 Semaphorins, SEM3A) and NRP1 proteolytic enzyme (A Disintegrin and Metalloproteinase 9, ADAM9).…”
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Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway
Published 2022“…Additionally, after β-catenin silencing, OA treatment significantly increased the expression of nuclear transcription factors SREBP-1 and TCF4, whereas Ex-4 significantly decreased this upregulation. Our findings suggest that direct activation of GLP-1R by Ex-4 reduces OA-induced steatosis in HepG2 cells by reducing fatty acid uptake and transport via FABP1 downregulation.…”
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The Aftermath Of COVID-19 on Grade 9 and 12 Biology Classes in Lebanon
Published 2024“…The purpose of this thesis was to explore the aftermath of COVID-19 in Grade 9 and 12 Biology Classes in Lebanon. The focus of the study was on comparing the content and skills covered in grade 9 and 12 biology curriculums and official exam levels before and after COVID-19 in addition to the teacher's perspective about the impact of online teaching on the learning process of the student’s experience and finding strategies to identify and fill the gaps. …”
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Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes
Published 2023“…Three DNAJB3 knockout (KO) lines were generated (KO 30, 44 and 47), using CRISPR-Cas9. Male and female KO and WT mice were fed a HF diet (45% kcal fat) for 16 weeks. …”
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Effect of heating rate on the pyrolysis of camel manure
Published 2022“…The results indicated that the increase in heating rates increased the starting and ending temperatures (decomposition) of manure components. …”
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Genetic engineering to enhance microalgal-based produced water treatment with emphasis on CRISPR/Cas9: A review
Published 2023“…<p dir="ltr">In recent years, the increased demand for and regional variability of available water resources, along with sustainable water supply planning, have driven interest in the reuse of produced water. …”
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Effect of the stretch rate during uniaxial testing on the mechanical properties of prolene
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Breaking the barriers towards large-scale microalgae-based bio-hydrogen production
Published 2025“…A CSTR nutrient-recovery line on digested <i>Scenedesmus</i> recovered 68 % N and 72 % P via struvite, reducing synthetic fertilizer ∼35 %; flue-gas CO<sub>2</sub> (12 % v/v) lifted biomass 22 % and reduced carbon-supplement cost 86 %. …”
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Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic anal...
Published 2020“…The total number of deaths increased from 50·7 million (49·5–51·9) in 2000 to 56·5 million (53·7–59·2) in 2019. …”
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Old subjects with sepsis in the emergency department: trend analysis of case fatality rate
Published 2019“…Over time the incidental admission rate (no. of sepsis-related admissions per 100 total admissions) increased from 4.1% (2009–2010) to 5.4% (2015–2016); P < 0.001, accompanied by a reduced CFR (from 38.0 to 18.4%; P < 0.001). …”
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Comparing WZB117-liposome Synthesis via Thin-film Hydration and Microfluidic Methods
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Increased Fracture Risk After Bariatric Surgery: a Case-Controlled Study with a Long-Term Follow-Up
Published 2022“…The mean duration of follow-up was 8.6 years. The fracture rate was higher in the surgical group as compared to the controls (9.4% vs 3.5%) with a crude odds ratio of 2.71 (95% CI 1.69–4.36). …”
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Anomalous Pressure Dependence of the Charge Density Wave and Fermi Surface Reconstruction in BaFe<sub>2</sub>Al<sub>9</sub>
Published 2025“…<p dir="ltr">We investigate the pressure evolution of charge density wave (CDW) order in the intermetallic compound BaFe<sub>2</sub>Al<sub>9,</sub> which undergoes a pronounced first-order CDW transition ∼1 1 2 K at ambient pressure. …”
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A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase
Published 2015“…In vitro experiments also showed that 15-HETE induced HREC migration and tube formation in a NOX-dependent manner. Taken together our data suggest that 12/15-LOX is implicated in DR via a NOX-dependent mechanism.…”
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