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The Use of the Gene Expression Omnibus (GEO) Database to Study Gene Expression and Methylation Patterns in Cases of Preterm Birth and Associated Diseases
Published 2023“…Future work could be done through further understanding of the relevant genes’ function and their pathways and strengthening the validity of the expression patterns in promoting PTB by determining any overlap between the different datasets submitted.…”
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Variational Auto Encoder Approach To Find Deferentially Expressed Genes
Published 2022“…Recently, deep learning models such as Autoencoder (AE) and Variational Autoencoder (VAE) models are being used to capture hidden patterns from single-cell gene expression data. In this paper, I proposed a framework that is based on a variational autoencoder called BiDiffVAE (Bi-directional Differential Variational Autoencoder) to extract differently expressed genes. …”
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3
BioNetApp: An interactive visual data analysis platform for molecular expressions
Published 2019“…</p><h3>Conclusion</h3><p dir="ltr">BioNetApp has been utilized in a metabolomics study to investigate the metabolite abundance changes in alcohol induced fatty liver, where pair-wise analyses of metabolome concentration revealed correlation networks and interesting patterns in the metabolomics dataset. This study case demonstrates the effectiveness of the BioNetApp software as an interactive visual analysis tool for molecular expression data in systems biology. …”
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A SAGE (Serial analysis of gene expression) view of breast tumor progression
Published 2001“…Very few genes were universally up-regulated in all tumors regardless of their stage and histological grade, indicating a high degree of diversity at the molecular level that likely reflects the clinical heterogeneity characteristic of breast carcinomas. Tumors of different histology type and stage had very distinct gene expression patterns. …”
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Combinatorial Expression Rules of Ion Channel Genes in Juvenile Rat (Rattus norvegicus) Neocortical Neurons
Published 2012“…Using expression data from a subset of twenty-six ion channel genes in ten different neocortical neuronal types, classified according to their electrophysiological properties, morphologies and anatomical positions, we first developed an incremental Support Vector Machine (iSVM) model that prioritizes the predictive value of single and combinations of genes for the rest of the expression pattern. …”
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Patterns of Rectal Temperature and Shipping Fever Incidence in Horses Transported Over Long-Distances
Published 2019“…It has been shown that the incidence of transport-related pyrexia in horses increases with travel time and distance, however, this incidence rate has been expressed as the cumulative number of horses showing pyrexia with the length of travel time during road transport (cumulative percentage), which does not accurately reflect the actual temperature fluctuations and their patterns in relation to shipping fever. …”
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Comparative transcriptomics of primary cells in vertebrates
Published 2020“…Motif activity analysis showed that both promoters and enhancers are activated by the same transcription factors in different species. An analysis of expression levels of mature miRNAs and of primary miRNAs identified by CAGE revealed that evolutionary old miRNAs are more likely to have conserved expression patterns than young miRNAs. …”
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Hyperosmotic Stress Induces a Specific Pattern for Stress Granule Formation in Human-Induced Pluripotent Stem Cells
Published 2021“…Gradient concentrations of NaCl showed a different pattern of SG formation between hiPSCs/IMR90-1 and the nonpluripotent cell line SH-SY5Y. …”
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A General Model for Pointing Error of High Frequency Directional Antennas
Published 2022“…For this aim, we first derive the probability density function (PDF) and cumulative distribution functions (CDF) of the pointing error between an unstable transmitter (Tx) and receiver (Rx), that have different antenna patterns and for which the vibrations are not similar in the Yaw and Pitch directions. …”
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Predictive Engineering the Membrane Composition of Neocortical Neurons
Published 2011“…In the first study, I investigate the single-cell gene expression patterns of ion channels in different neuron types and present a combinatorial rule extractor model that reverse engineers the observed expression rules in ten different neocortical neuron types. …”
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11
Cell surface proteome characterization of the Candida albicans DSE1 mutant. (c2011)
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masterThesis -
12
Claudin-1, A Double-Edged Sword in Cancer
Published 2020“…Furthermore, we utilized expression data from The Cancer Genome Atlas (TCGA) to investigate the association between CLDN-1 expression and overall survival (OS) in different cancer types. …”
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Detection of statistically significant network changes in complex biological networks
Published 2017“…It can happen that due to gene mutations, as for example when cancer progresses, the gene expression network undergoes some amount of localized re-wiring. …”
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Digital diplomacy during the first 100 days: How GCC ministries of foreign affairs and ministers tweeted the blockade
Published 2021“…In general, states tweet on a daily basis, and the ways in which a sovereign state presents itself online offers an insight into the patterns of representation of state identity, strategy, emotional expression, and recognition of others. …”
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Molecular, antibiogram and serological typing of Staphylococcus aureus isolates recovered from Al-Makased hospital in East Jerusalem
Published 2002“…Moreover, type 5 isolates showed identical patterns (one isolate differed from the rest with one band only). …”
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Divergent wiring of repressive and active chromatin interactions between mouse embryonic and trophoblast lineages
Published 2018“…Interactions that are prominent in TSCs are enriched for enhancer–gene contacts involving key TSC transcription factors, as well as TET1, which helps to maintain the expression of TSC-relevant genes. Our work shows that the first developmental cell fate decision results in distinct chromatin conformation patterns establishing lineage-specific contexts involving both repressive and active interactions.…”
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Epigenetic alteration of the dopamine transporter gene in alcohol-dependent patients is associated with age
Published 2012“…Genetic and environmental factors have been shown to modulate susceptibility to alcohol dependence, and both may act through epigenetic mechanisms that can modulate gene expression, e.g. DNA methylation at CpG sites. Recent studies have suggested that DNA methylation patterns may change over time. …”
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DNA methylation profiling in Trisomy 21 females with and without breast cancer
Published 2023“…We analyzed DNA methylation patterns in Trisomy 21 (T21) individuals without breast cancer (T21-BCF) and DS individuals with breast cancer (T21-BC), using the Infinium Methylation EPIC BeadChip array.…”
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DIAPH3 predicts survival of patients with <i>MGMT</i>-methylated glioblastoma
Published 2024“…</p><h3>Methods</h3><p dir="ltr">We analyzed <i>DIAPH3</i> expression in glioblastoma samples from the cancer genome atlas (TCGA). …”
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Comparison of Whole-class Discussion and Task-based Activity: A Small-Scale Study
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doctoralThesis