APP deficiency did not affect the mRNA level of <i>Scn8a</i> in cerebellar PCs. od Miao-Jin Ji (22676552)

Teme:

Source data and statistical details for figures. od Miao-Jin Ji (22676552)

Teme:

L7 promoter-driven Cre recombinase expression is restricted to PCs in the cerebellar cortex. od Miao-Jin Ji (22676552)

Teme:

Nav1.6 mediated the deficits of PC firing and motor function in APP-null mice. od Miao-Jin Ji (22676552)

Teme:

Raw images for blots. od Miao-Jin Ji (22676552)

Teme:

Exogenous APP expression restored the Nav1.6 currents and ameliorated the abnormalities in the firing patterns of PCs of APP-null mice. od Miao-Jin Ji (22676552)

Teme:

Antibody validation for Nav1.6 and Nav1.1-EGFP in transfected HEK293 cells. od Miao-Jin Ji (22676552)

Teme:

xxx. od Miao-Jin Ji (22676552)

Teme:

APP deficiency does not alter PC development or induce degeneration. od Miao-Jin Ji (22676552)

Teme:

APP deficiency selectively reduces Nav1.6-mediated Na⁺ currents in cerebellar PCs. od Miao-Jin Ji (22676552)

Teme:

Nav1.6 Mediates most of the persistent and resurgent sodium currents in cerebellar PCs. od Miao-Jin Ji (22676552)

Teme:

APP-null mice exhibit motor function deficits. od Miao-Jin Ji (22676552)

Teme:

Exogenous amyloid precursor protein (APP) expression restored the defects of the sIPSCs evoked by Nav1.6-mediated Purkenji cell inputs in APP-null mice. od Miao-Jin Ji (22676552)

Teme:

Cerebellar Purkinje cell (PC)-specific amyloid precursor protein (APP) expression modulates motor function. od Miao-Jin Ji (22676552)

Teme:

PoTX potentiates persistent sodium currents in APP-null PCs. od Miao-Jin Ji (22676552)

Teme:

Validation of Nav1.6 and Nav1.1 contributions to sodium currents in PCs. od Miao-Jin Ji (22676552)

Teme:

Full-length APP is required for the rescue of motor deficit in APP-null mice. od Miao-Jin Ji (22676552)

Teme:

APP deficiency impairs the normal firing patterns of PCs. od Miao-Jin Ji (22676552)

Teme: