Discovery of therapeutic compounds targeting brain metastasis-associated tumor cells (MBMATCs) in high MBM-Index melanoma. ‌ Jingxin Zeng (18773484)

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Single cell RNA-seq and snRNA-seq profiling of the PTs (primary melanoma), ECMs (extracranial melanoma metastases) and MBMs (melanoma brain metastases) environments. ‌ Jingxin Zeng (18773484)

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Marker genes in melanoma tumor cells across PT, ECM and MBM by sc/snRNA-seq. ‌ Jingxin Zeng (18773484)

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scRNA-seq and snRNA-seq profiling of 26 melanoma samples. ‌ Jingxin Zeng (18773484)

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AXL and MITF signature genes. ‌ Jingxin Zeng (18773484)

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The MBM-Index showed no significant correlation with clinicopathological features. ‌ Jingxin Zeng (18773484)

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Interaction between MBMATCs and the immune microenvironment. ‌ Jingxin Zeng (18773484)

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Pseudotime trajectory analysis of melanoma clusters Mela4 and Mela5. ‌ Jingxin Zeng (18773484)

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Identification of therapeutic drugs with high drug sensitivity for brain metastasis-associated tumor cells (MBMATCs) and high-brain metastasis (MBM) index patients. ‌ Jingxin Zeng (18773484)

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The enriched pathway by all transcripts differentially expressed between MBMATCs and other tumor cells, and between MBM-High and MBM-Low groups. ‌ Jingxin Zeng (18773484)

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Immune landscape and CD8⁺ T cell transition states in PTs, ECMs and MBMs. ‌ Jingxin Zeng (18773484)

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Immune cells profiling in PTs, ECMs and MBMs. ‌ Jingxin Zeng (18773484)

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Identification of melanoma brain metastasis-associated tumor cell subpopulations (MBMATCs). ‌ Jingxin Zeng (18773484)

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Samples & cell type composition in melanoma tumor cells. ‌ Jingxin Zeng (18773484)

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Samples & cell type composition in sc/snRNA-seq. ‌ Jingxin Zeng (18773484)

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Tumor cell-specific transcriptomic features across PTs, ECMs and MBMs. ‌ Jingxin Zeng (18773484)

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Fluvastatin inhibits the migration of melanoma A375 cells in a wound healing assay. ‌ Jingxin Zeng (18773484)

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The MBM-Index as an independent predictor of overall survival (OS) in melanoma. ‌ Jingxin Zeng (18773484)

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Associations of categories of social isolation and social support with trajectories of self-rated health, across the four years prior to and following incident heart failure hospit... ‌ Kennedy M. Peter-Marske (19267951)

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Associations of social isolation and social support (SS) measured prior to heart failure with time to first all-cause rehospitalization and all-cause mortality after incident heart... ‌ Kennedy M. Peter-Marske (19267951)

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