Čájehuvvojit 1 - 20 oktiibuot 20 bohtosis ohcui "Mouse"', ohcanáigi: 0,02s Aiddostahte ozu
  1. 1
    Source data for "EPI-SauriCas9-Based Mouse Ovarian Cancer Models Recapitulating PTEN Deletion in Patients"

    Source data for "EPI-SauriCas9-Based Mouse Ovarian Cancer Models Recapitulating PTEN Deletion in Patients" Dahkki Wutao Chen (22061138)

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  2. 2
    Supplemental figures for "Exercise enhances antioxidant protein levels in oxidative skeletal muscle via IL-1β"

    Supplemental figures for "Exercise enhances antioxidant protein levels in oxidative skeletal muscle via IL-1β" Dahkki Mami Yamada (1271472)

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  3. 3
    The protein expression of VDAC1 in <i>A. cantonensis</i>-infected mice after albendazole and 3-HBA treatment.

    The protein expression of VDAC1 in <i>A. cantonensis</i>-infected mice after albendazole and 3-HBA treatment. Dahkki Yi-Hao Huang (5983352)

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  4. 4
    The protein expression of cytochrome c in <i>A. cantonensis</i>-infected mice after albendazole and 3-HBA treatment.

    The protein expression of cytochrome c in <i>A. cantonensis</i>-infected mice after albendazole and 3-HBA treatment. Dahkki Yi-Hao Huang (5983352)

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  5. 5
    Evaluation of the body weight changes in BALB/c mice after <i>Angiostrongylus cantonensis</i> infection or therapeutic treatment.

    Evaluation of the body weight changes in BALB/c mice after <i>Angiostrongylus cantonensis</i> infection or therapeutic treatment. Dahkki Yi-Hao Huang (5983352)

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  6. 6
    Evaluation of the effect of 3-HBA on vascular congestion in BALB/c mice after <i>A. cantonensis</i> infection.

    Evaluation of the effect of 3-HBA on vascular congestion in BALB/c mice after <i>A. cantonensis</i> infection. Dahkki Yi-Hao Huang (5983352)

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  7. 7
    The protein expression of GFAP and mitochondria-related proteins in <i>A. cantonensis</i> L5 soluble antigen stimulated astrocytes.

    The protein expression of GFAP and mitochondria-related proteins in <i>A. cantonensis</i> L5 soluble antigen stimulated astrocytes. Dahkki Yi-Hao Huang (5983352)

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  8. 8
    The effects of 3-HBA on GFAP and mitochondria-related proteins expression in <i>A.</i> <i>cantonensis</i> L5 soluble antigen stimulated astrocytes.

    The effects of 3-HBA on GFAP and mitochondria-related proteins expression in <i>A.</i> <i>cantonensis</i> L5 soluble antigen stimulated astrocytes. Dahkki Yi-Hao Huang (5983352)

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  9. 9
    Evaluation of the effect of 3-HBA on eosinophilic meningitis in BALB/c mice after <i>A. cantonensis</i> infection.

    Evaluation of the effect of 3-HBA on eosinophilic meningitis in BALB/c mice after <i>A. cantonensis</i> infection. Dahkki Yi-Hao Huang (5983352)

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  10. 10
    Evaluation of the effect of 3-HBA on hemorrhage in BALB/c mice after <i>A. cantonensis</i> infection.

    Evaluation of the effect of 3-HBA on hemorrhage in BALB/c mice after <i>A. cantonensis</i> infection. Dahkki Yi-Hao Huang (5983352)

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  11. 11
    The protein expression of MCU in <i>A. cantonensis</i>-infected mice after albendazole and 3-HBA treatment.

    The protein expression of MCU in <i>A. cantonensis</i>-infected mice after albendazole and 3-HBA treatment. Dahkki Yi-Hao Huang (5983352)

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  12. 12
    The protein expression of GFAP in <i>A. cantonensis</i>-infected mice after albendazole and 3-HBA treatment.

    The protein expression of GFAP in <i>A. cantonensis</i>-infected mice after albendazole and 3-HBA treatment. Dahkki Yi-Hao Huang (5983352)

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  13. 13
    Immunofluorescence analysis of GFAP and mitochondria-related proteins after 3-HBA treatment in <i>A. cantonensis</i> L5 soluble antigen stimulated astrocytes.

    Immunofluorescence analysis of GFAP and mitochondria-related proteins after 3-HBA treatment in <i>A. cantonensis</i> L5 soluble antigen stimulated astrocytes. Dahkki Yi-Hao Huang (5983352)

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  14. 14
    Evaluation of the effect of 3-HBA on larval presence in BALB/c mice after <i>A. cantonensis</i> infection.

    Evaluation of the effect of 3-HBA on larval presence in BALB/c mice after <i>A. cantonensis</i> infection. Dahkki Yi-Hao Huang (5983352)

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  15. 15
    A. Mouse transcriptome non-negative matrix factorization component weights across all time points and conditions. Larger weight values indicate components with upregulated genes dominating. B. Gene set enrichment plot for selected features from each component in panel A. Components 1, 4, and 5 did not exhibit enrichment in these broad terms. C. Number of genes in enriched gene ontology terms related to immunity, signaling, and transcription for each time point and condition. D. Time course transcriptional profiles for mouse genes characteristic to component 3. E. PARFA-seq validation by quantitative PCR and gene expression changes during immortalized bone marrow-derived macrophage infection by <i>T. gondii</i> assessed by quantitative PCR.

    A. Mouse transcriptome non-negative matrix factorization component weights across all time points and conditions. Larger weight values indicate components with upregulated genes do... Dahkki Dominykas Murza (22676289)

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  16. 16
    A. <i>T. gondii</i> gene group changes throughout the time course, expressed as log<sub>2</sub>(fold change) relative to pre-infection tachyzoites (t = 0). Grey area depicts the 95% confidence interval. n value refers to number of genes detected in each group. B. Gene set enrichment plot for most enriched terms from <i>T. gondii</i> transcriptome features at 15 min to 120 min. Five most significant terms are displayed for each database. C and D. Transcriptional profiles of top five upregulated and downregulated <i>T. gondii</i> transcription factors, respectively.

    A. <i>T. gondii</i> gene group changes throughout the time course, expressed as log<sub>2</sub>(fold change) relative to pre-infection tachyzoites (t = 0). Grey area depicts the 95... Dahkki Dominykas Murza (22676289)

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  17. 17
    Oligonucleotides used in this study.

    Oligonucleotides used in this study. Dahkki Dominykas Murza (22676289)

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  18. 18
    A. Library preparation strategy: poly-A(+) RNAs are captured by complementarity to reverse transcription primer, then second strand is synthesized using random hexamers and handles for sequencing are attached through two rounds of PCR. B. Mapped read distribution by species and by biotype. C and D. Principal component analysis of mouse and <i>T. gondii</i> transcriptomes, respectively. E and F. Volcano plots of Live <i>Toxoplasma</i>-infected mouse and <i>T. gondii</i> time points, respectively. To calculate Log<sub>2</sub>(Fold change), every timepoint is compared to corresponding samples (either macrophage or <i>Toxoplasma</i>) before infection (t = 0 min). Most significant and most upregulated transcripts are labelled. Number of significantly (p ≤ 0.05) downregulated and upregulated genes for each time point is given in blue and red, respectively. In F, 24-hour time point, red dots mark ROP

    A. Library preparation strategy: poly-A(+) RNAs are captured by complementarity to reverse transcription primer, then second strand is synthesized using random hexamers and handles... Dahkki Dominykas Murza (22676289)

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  19. 19
    A. Experimental scheme of infection time course and downstream workflow; B. Optimization of tachyzoite concentration to achieve adequate infection rates, with a threshold set at 50% infection efficiency. Error bars represent ± 1 standard deviation. Corresponding MOI values are given for each condition; C. Infection time course micrograph merged from brightfield and green channels. <i>T. gondii</i> exhibits green fluorescence due to stable GFP expression in the strain used. Percentage at the top left indicates infection efficiency (± 1 standard deviation) for each time point.

    A. Experimental scheme of infection time course and downstream workflow; B. Optimization of tachyzoite concentration to achieve adequate infection rates, with a threshold set at 50... Dahkki Dominykas Murza (22676289)

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  20. 20
    Summary of all significant gene enrichment terms for every condition (as combination of sample type and timepoint).

    Summary of all significant gene enrichment terms for every condition (as combination of sample type and timepoint). Dahkki Dominykas Murza (22676289)

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