Source Data For All Files and Figures. حسب Ashley N. Hayden (19871128)

الموضوعات:

Copy number variants in <i>YBX1</i> and <i>YBX3</i> found in individuals with neurological symptoms and <i>in vivo</i> modeling of a predicted pathogenic single nucleotide variant... حسب Ashley N. Hayden (19871128)

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Location of the Asn127 residue based on Alphafold visualization of the human YBX3 protein. حسب Ashley N. Hayden (19871128)

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CNV gains and losses data for <i>YBX3</i> in DECIPHER [94]. حسب Ashley N. Hayden (19871128)

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Human <i>YBX1</i> and <i>YBX3</i> functionally replace <i>cey-1</i> in memory <i>in vivo</i> and insertion of a rare SNV into <i>YBX3</i> disrupts ITM. حسب Ashley N. Hayden (19871128)

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RNAi-based knockdown of RBPs does not have any detectable effect on learning ability. حسب Ashley N. Hayden (19871128)

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Results of targeted screen of 20 RBPs reveals both known and novel associative memory regulators. حسب Ashley N. Hayden (19871128)

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Targeted screen of 20 conserved neuronal RBPs reveals eight novel associative memory regulators. حسب Ashley N. Hayden (19871128)

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Images generated from publicly available VISTA (Visualizing the Spatial Transcriptome of the <i>C</i>. <i>elegans</i> Nervous System) [63]reveal differences in expression across ea... حسب Ashley N. Hayden (19871128)

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Summarized results of targeted screen of 20 RBPs. حسب Ashley N. Hayden (19871128)

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Data from multiple transcriptomic datasets as well as microscopy images reveal broad expression of CEY-1 in the nervous system of adult worms. حسب Ashley N. Hayden (19871128)

الموضوعات:

CNV gains and losses data for <i>YBX1</i> in DECIPHER [94]. حسب Ashley N. Hayden (19871128)

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<i>cey-1</i> loss-of-function mutants as well as worms with neuron-specific rescue of <i>cey-1</i> (<i>cey-1(rrr12)</i>; <i>rab-3p</i>::<i>CEY-1</i>) have no deficits in butanone s... حسب Ashley N. Hayden (19871128)

الموضوعات:

CEY-1 promotes learning and memory in the <i>C</i>. <i>elegans</i> nervous system. حسب Ashley N. Hayden (19871128)

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Humanized lines expressing <i>YBX1</i> or <i>YBX3</i>, including those with a SNV in <i>YBX3</i>, have normal butanone sensing and motility. حسب Ashley N. Hayden (19871128)

الموضوعات:

CEY-1 is the closest ortholog to the human Y-box binding proteins. حسب Ashley N. Hayden (19871128)

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Introduction of a point mutation from human individuals into <i>cey-1 (cey-1 (p</i>.<i>Asn56Tyr))</i> does not cause butanone sensing or motility defects. حسب Ashley N. Hayden (19871128)

الموضوعات:

Knockdown of <i>cey-1</i> specifically in the adult nervous system does not impair butanone sensing or motility. حسب Ashley N. Hayden (19871128)

الموضوعات:

Detailed information for all individuals with CNV deletions in <i>YBX1</i> or <i>YBX3</i> included in Fig 4 and accompanying DECIPHER phenotypic data. حسب Ashley N. Hayden (19871128)

الموضوعات:

RNAi-based knockdown of RBPs does not have any detectable effect on butanone sensing. حسب Ashley N. Hayden (19871128)

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