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"protocol development" » "process development" (Expand Search), "local development" (Expand Search)
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Ultrasound-Guided Therapies in the Neuro ICU
Published 2021“…Recently published consensus statement on the recommended skills and competence level required to perform brain ultrasonography in the critical care setting may serve as a helpful framework to guide further training and protocol development. Summary Utilization of systemic sonography has grown as a diagnostic and procedural aid in the critical care setting, while the rising body of literature continues to demonstrate the value of routine use of neurovascular ultrasound. …”
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β-cell mitochondria in diabetes mellitus: a missing puzzle piece in the generation of hPSC-derived pancreatic β-cells?
Published 2022“…Because impaired insulin secretion due to dysfunction or loss of pancreatic β-cells underlies different types of diabetes, research has focused its effort towards the generation of pancreatic β-cells from human pluripotent stem cell (hPSC) as a potential source of cells to compensate for insulin deficiency. However, many protocols developed to differentiate hPSCs into insulin-expressing β-cells in vitro have generated hPSC-derived β-cells with either immature phenotype such as impaired glucose-stimulated insulin secretion (GSIS) or a weaker response to GSIS than cadaveric islets. …”
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Somatic mutations in Middle East and North Africa breast cancer patients: a systematic review
Published 2025“…Our findings underscore the urgent need for establishing a MENA Breast Cancer Genomics Consortium to standardize sequencing protocols, develop locally validated gene panels, and create regional variant databases that capture the unique mutation spectrum of these populations. …”