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Immunomodulatory effects of tumor Lactate Dehydrogenase C (LDHC) in breast cancer
Published 2025“…Following <i>LDHC</i> knockdown, we observed an increase in the secretion of tumor-derived pro-inflammatory cytokines (IFN-γ, GM-CSF, MCP-1, CXCL1), a decrease in the soluble levels of tumor-derived immunosuppressive factors (IL-6, Gal-9) and reduced tumor cell surface PD-L1 expression. …”
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2
LDL-C Targets in Secondary Prevention: How Low Should We Go?
Published 2019“…There still remains a question of the cost-effectiveness of some non-statin therapies particularly PCSK9 inhibitors, in spite of recent price decreases, and whether the benefit is worth the cost.…”