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"b marked decrease" » "b marked increase" (Expand Search), "_ marked decrease" (Expand Search), "a marked decrease" (Expand Search), "_ market decrease" (Expand Search)
"i large increases" » "_ large increases" (Expand Search), "a large increases" (Expand Search), "via large increases" (Expand Search), "i large increased" (Expand Search), "i large increase" (Expand Search)
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Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer
Published 2024“…Mechanistically, compound <b>E35</b> markedly decreased the expression of Skp2, as well as increased the expression of its substrates p21 and p27. …”
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Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer
Published 2024“…Mechanistically, compound <b>E35</b> markedly decreased the expression of Skp2, as well as increased the expression of its substrates p21 and p27. …”
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Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer
Published 2024“…Mechanistically, compound <b>E35</b> markedly decreased the expression of Skp2, as well as increased the expression of its substrates p21 and p27. …”
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Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer
Published 2024“…Mechanistically, compound <b>E35</b> markedly decreased the expression of Skp2, as well as increased the expression of its substrates p21 and p27. …”
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Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer
Published 2024“…Mechanistically, compound <b>E35</b> markedly decreased the expression of Skp2, as well as increased the expression of its substrates p21 and p27. …”
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Macrophage autophagy protects against acute kidney injury by inhibiting renal inflammation through the degradation of TARM1
Published 2024“…Similar results were also obtained in vitro that bone marrow-derived macrophages (BMDMs) lacking <i>Atg5</i> largely increased pro-inflammatory cytokine expression in response to LPS and IFNG. …”
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The spatial distribution of Bgs4 in <i>ync13</i><i>Δ</i> cells depends on Rng10.
Published 2025“…Arrows in <b>(A)</b> mark Ags1 concentrated at the center of the division plane after ring constriction and in <b>(B)</b> mark decreased Bgs4 level at the septal edges. <b>(D</b> and <b>E)</b> Gaussian fits of fluorescence intensity of Bgs4 <b>(D)</b> and Bgs1 <b>(E)</b> along the division site at the end of ring constriction in WT or <i>ync13Δ</i> cells. …”
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Knockdown of Rab2A improves diet-induced hepatic lipid accumulation.
Published 2022“…<p><b>(A)</b> Marked decreased protein levels of PPARγ were found in Rab2A-knockdown liver samples. …”
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Rab2A regulates cellular lipid accumulation.
Published 2022“…. “*” indicates <i>p</i> < 0.05. <b>(K)</b> Marked decreases in PPARγ-targeted genes were found in Rab2A-knockdown HepG2 cells. …”
