Cost and benefits estimation methods. Autor Julie Abimanyi-Ochom (3924842)

“…The results affirm the strong cost-effectiveness potential of the initial CTC trial implementation in Australia. Moreover, conducting further cost-benefit modelling for additional outcomes and beyond the intervention’s timeframe is likely to enhance the economic viability of the CTC trial.…”

Benefit-cost model inputs. Autor Julie Abimanyi-Ochom (3924842)

“…The results affirm the strong cost-effectiveness potential of the initial CTC trial implementation in Australia. Moreover, conducting further cost-benefit modelling for additional outcomes and beyond the intervention’s timeframe is likely to enhance the economic viability of the CTC trial.…”

table_1_Indoleamine 2,3-Dioxygenase Expression Pattern in the Tumor Microenvironment Predicts Clinical Outcome in Early Stage Cervical Cancer.xlsx Autor A. Marijne Heeren (5501072)

“…Our data thus indicate that the serum kyn/trp ratio and IDO expression in primary tumor samples are not clear-cut biomarkers for prognosis and stratification of patients with early stage cervical cancer for clinical trials implementing IDO inhibitors. Rather, a marginal IDO expression pattern in the tumor dominantly predicts favorable outcome, which might be related to IFNγ release in the cervical tumor microenvironment.…”

Delphi flowchart. Autor Charis Xuan Xie (18605141)

“…Having an agreed definition will allow better trial implementation and facilitate effective communication and decision-making across stakeholders. …”

Key themes synthesised from literature review. Autor Charis Xuan Xie (18605141)

“…Having an agreed definition will allow better trial implementation and facilitate effective communication and decision-making across stakeholders. …”

table_2_Indoleamine 2,3-Dioxygenase Expression Pattern in the Tumor Microenvironment Predicts Clinical Outcome in Early Stage Cervical Cancer.docx Autor A. Marijne Heeren (5501072)

“…Our data thus indicate that the serum kyn/trp ratio and IDO expression in primary tumor samples are not clear-cut biomarkers for prognosis and stratification of patients with early stage cervical cancer for clinical trials implementing IDO inhibitors. Rather, a marginal IDO expression pattern in the tumor dominantly predicts favorable outcome, which might be related to IFNγ release in the cervical tumor microenvironment.…”

Trial efficiency pentagon. Autor Charis Xuan Xie (18605141)

“…Having an agreed definition will allow better trial implementation and facilitate effective communication and decision-making across stakeholders. …”

Embodied decision setup and active inference model. Autor Matteo Priorelli (21568266)

“…Finally, in the fourth process, the prior over the correct target is updated across trials, implementing habitual learning. Of note, some readers may find the edge from (the agent’s belief about the latent state) to (an observation) somewhat unconventional. …”

Study design. Autor Karisa Parkington (21799480)

“…This pilot trial will determine the feasibility of, and provide clinical parameter estimates for, future larger trials implementing DHM platforms in TRD. This area of study might emphasize the need for personalized treatment protocols in TRD that integrate digital tools to augment the standard of care, ultimately leading to the development and advancement of more targeted and effective interventions.…”

Data_Sheet_1_TCR Fingerprinting and Off-Target Peptide Identification.xlsx Autor Armen R. Karapetyan (7523447)

“…<p>Adoptive T cell therapy using patient T cells redirected to recognize tumor-specific antigens by expressing genetically engineered high-affinity T-cell receptors (TCRs) has therapeutic potential for melanoma and other solid tumors. Clinical trials implementing genetically modified TCRs in melanoma patients have raised concerns regarding off-target toxicities resulting in lethal destruction of healthy tissue, highlighting the urgency of assessing which off-target peptides can be recognized by a TCR. …”

image_1_Indoleamine 2,3-Dioxygenase Expression Pattern in the Tumor Microenvironment Predicts Clinical Outcome in Early Stage Cervical Cancer.tif Autor A. Marijne Heeren (5501072)

“…Our data thus indicate that the serum kyn/trp ratio and IDO expression in primary tumor samples are not clear-cut biomarkers for prognosis and stratification of patients with early stage cervical cancer for clinical trials implementing IDO inhibitors. Rather, a marginal IDO expression pattern in the tumor dominantly predicts favorable outcome, which might be related to IFNγ release in the cervical tumor microenvironment.…”

Data_Sheet_1_The Implementation of a Primary Care-Based Integrated Mobile Health Intervention for Stroke Management in Rural China: Mixed-Methods Process Evaluation.docx Autor Enying Gong (843920)

“…This study reports the findings from the trial implementation and process evaluation that investigate the implementation of the intervention and inform factors that may influence the wider implementation of the intervention in the future.…”

Summary of characteristics of included papers. Autor Mridula Shankar (7832636)

“…For research staff, developing reciprocal relationships with health workers, having access to resources for trial implementation, ensuring the trial was visible to potential participants and health workers, implementing a woman-centred approach when communicating with potential participants, and emotional orientations towards the trial were factors perceived to affect recruitment. …”

Incidence of eclampsia and related complications across 10 low- and middle-resource geographical regions: Secondary analysis of a cluster randomised controlled trial Autor Nicola Vousden (5023244)

“…</p><p>Methods and findings</p><p>This is a secondary analysis of a stepped-wedge cluster randomised controlled trial undertaken in sub-Saharan Africa, India, and Haiti. This trial implemented a novel vital sign device and training package in routine maternity care with the aim of reducing a composite outcome of maternal mortality and morbidity. …”

Summary of qualitative findings. Autor Mridula Shankar (7832636)

“…For research staff, developing reciprocal relationships with health workers, having access to resources for trial implementation, ensuring the trial was visible to potential participants and health workers, implementing a woman-centred approach when communicating with potential participants, and emotional orientations towards the trial were factors perceived to affect recruitment. …”