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1
Intercalator binding is limited to linker and NFR DNA in the presence of nucleosomes.
Published 2019“…<p>(A) Reduction of EBr staining following brief MNase digestion of formaldehyde fixed HeLa H2B-GFP nuclei. (B) Marked increase in DNase I hypersensitivity following core nucleosome destabilisation. …”
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2
Effects of enalapril and paricalcitol treatment on diabetic nephropathy and renal expressions of TNF-α, p53, caspase-3 and Bcl-2 in STZ-induced diabetic rats - Fig 6
Published 2019“…<p>Photomicrographs of pancreas sections showing no histopathological changes in normal group (A), necrosis (arrow) and decrease in the size of islets of diabetic control group (B), marked increase of islet size and vacuolations (arrow) in diabetic group treated with enalapril (C), intact islet in diabetic group treated with paricalcitol (D) and relatively large-sized islets with highly active divided cells in diabetic group treated with a combination of enalapril and paricalcitol (E). …”
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3
Rab2A regulates cellular lipid accumulation.
Published 2022“…Free-Flag versus Flag-Rab2A (<i>n</i> = 3 per group). <b>(F)</b> Marked increases in PPARγ-targeted genes were observed in Rab2A-overexpressing HepG2 cells. …”
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4
Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer
Published 2024“…Mechanistically, compound <b>E35</b> markedly decreased the expression of Skp2, as well as increased the expression of its substrates p21 and p27. …”
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5
Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer
Published 2024“…Mechanistically, compound <b>E35</b> markedly decreased the expression of Skp2, as well as increased the expression of its substrates p21 and p27. …”
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6
Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer
Published 2024“…Mechanistically, compound <b>E35</b> markedly decreased the expression of Skp2, as well as increased the expression of its substrates p21 and p27. …”
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7
Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer
Published 2024“…Mechanistically, compound <b>E35</b> markedly decreased the expression of Skp2, as well as increased the expression of its substrates p21 and p27. …”
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8
Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer
Published 2024“…Mechanistically, compound <b>E35</b> markedly decreased the expression of Skp2, as well as increased the expression of its substrates p21 and p27. …”
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9
The spatial distribution of Bgs4 in <i>ync13</i><i>Δ</i> cells depends on Rng10.
Published 2025“…Arrows in <b>(A)</b> mark Ags1 concentrated at the center of the division plane after ring constriction and in <b>(B)</b> mark decreased Bgs4 level at the septal edges. <b>(D</b> and <b>E)</b> Gaussian fits of fluorescence intensity of Bgs4 <b>(D)</b> and Bgs1 <b>(E)</b> along the division site at the end of ring constriction in WT or <i>ync13Δ</i> cells. …”
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10
Knockdown of Rab2A improves diet-induced hepatic lipid accumulation.
Published 2022“…<p><b>(A)</b> Marked decreased protein levels of PPARγ were found in Rab2A-knockdown liver samples. …”