Data_Sheet_1_Engineering circular bacteriocins: structural and functional effects of α-helix exchanges and disulfide introductions in circularin A.PDF حسب Fangfang Liu (185161)

"…The introduction of cysteines for potential disulfide bonds resulted in a substantial reduction in bacteriocin biosynthesis and/or bioactivity, indicating the importance of maintaining dynamic flexibility of α-helices in circularin A, while reduction of the potential disulfide in one case increased the activity. The 5 α-helices of circularin A were respectively replaced by corresponding helices from another circular peptide, enterocin AS-48, and modestly active peptides were obtained in a few cases. …"

Proteome database of Staphylococcus aureus NCTC 8325 حسب Wenfa Ng (444092)

"…In <i>S. aureus</i> case, increasing resistance to a variety of frontline antibiotics makes this bacterium of increasing medical concern, which motivates the search for a variety of biophysical and biochemical approaches for its eradication or keeping it under control. …"