Discovery of Oral AMP-Activated Protein Kinase Activators for Treating Hyperlipidemia حسب Mingchao Wang (450503)

الموضوعات:

Intercalator binding is limited to linker and NFR DNA in the presence of nucleosomes. حسب Rosevalentine Bosire (7901315)

"…<p>(A) Reduction of EBr staining following brief MNase digestion of formaldehyde fixed HeLa H2B-GFP nuclei. (B) Marked increase in DNase I hypersensitivity following core nucleosome destabilisation. …"

Effects of enalapril and paricalcitol treatment on diabetic nephropathy and renal expressions of TNF-α, p53, caspase-3 and Bcl-2 in STZ-induced diabetic rats - Fig 6 حسب Osama M. Ahmed (7392164)

"…<p>Photomicrographs of pancreas sections showing no histopathological changes in normal group (A), necrosis (arrow) and decrease in the size of islets of diabetic control group (B), marked increase of islet size and vacuolations (arrow) in diabetic group treated with enalapril (C), intact islet in diabetic group treated with paricalcitol (D) and relatively large-sized islets with highly active divided cells in diabetic group treated with a combination of enalapril and paricalcitol (E). …"

Table_1_Causal relationship between PCSK9 inhibitor and primary glomerular disease: a drug target Mendelian randomization study.xls حسب Hangyu Duan (17993554)

"…</p>Conclusions<p>PCSK9i markedly decreased the risk of IgAN, suggesting a potential mechanism beyond their primary effect on LDL-C. …"

Presentation_1_mRNA vaccines against SARS-CoV-2 induce comparably low long-term IgG Fc galactosylation and sialylation levels but increasing long-term IgG4 responses compared to an... حسب Jana Sophia Buhre (12295230)

"…</p>Results<p>We show that the initially high mRNA vaccine-induced blood and salivary anti-S IgG levels, particularly IgG1, markedly decrease over time and approach the lower levels induced with the adenovirus-based vaccine. …"

Rab2A regulates cellular lipid accumulation. حسب Zi-Yue Chen (11986539)

"…Free-Flag versus Flag-Rab2A (<i>n</i> = 3 per group). <b>(F)</b> Marked increases in PPARγ-targeted genes were observed in Rab2A-overexpressing HepG2 cells. …"