Identification of potential transcription factors that enhance human iPSC generation by Nuha T. Swaidan (18595219)

“…In this study, using RNA-seq platform we have identified and validated the differential gene expression of five transcription factors (TFs) (GBX2, NANOGP8, SP8, PEG3, and ZIC1) that were associated with a remarkable increase in the number of iPSC colonies generated from a patient with Parkinson's disease. …”

Early Nutrition and Risk of Type 1 Diabetes: The Role of Gut Microbiota by Elvira Verduci (3171957)

“…<p dir="ltr">Type 1 diabetes (T1D) appears most frequently in childhood, with an alarming increasing incidence in the last decades. …”

Comparative efficacy and safety of PD-1/PD-L1 inhibitors in triple negative breast cancer: a systematic review and network meta-analysis of randomized controlled trials by Ibrahim Elmakaty (14614270)

“…They were associated with an increase in immune-related adverse effects. When used early in the course of TNBC, PD-1/PD-L1 inhibitors exert their maximum benefit. …”

PDX1⁻/NKX6.1⁺ progenitors derived from human pluripotent stem cells as a novel source of insulin‐secreting cells by Bushra Memon (4792767)

“…We recently generated novel hPSC-derived pancreatic progenitors, expressing high levels of the transcription factor NKX6.1, in the absence of PDX1 (PDX1⁻/NKX6.1⁺). …”

Influence of temperature on tire-pavement noise in hot climates: Qatar case by Okan Sirin (14603304)

“…There is an apparent trend of decreasing temperature coefficient with increasing mean texture depth of dense graded asphalt pavements. …”

Shear Behavior of One-Way Reinforced Concrete Hollow Slabs Voided with PET Void Formers by Hasan, Haider H.

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Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... by Vijay Ganji (8710491)

There Is Selective Increase in Pro-thrombotic Circulating Extracellular Vesicles in Acute Ischemic Stroke and Transient Ischemic Attack: A Study of Patients From the Middle East an... by Abdelali Agouni (181926)

“…Acutely, within 48 h of attacks, there was an increase in total endothelial EVs in TIA (6.73 ± 1.77; <i>P</i> = 0.0156; <i>n</i> = 21) and AIS (11.23 ± 1.95; <i>P</i> = 0.0007; <i>n</i> = 66) patients compared to controls (2.04 ± 0.78; <i>n</i> = 24). …”

Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema by Diab, Khalil J.

“…Measurements and Main Results: Consistent with previously reported de novo activation of ceramide synthesis, VEGFR inhibition triggered increases in lung ceramides, dihydroceramides, and dihydrosphingosine, but did not alter sphingosine kinase activity or S1P levels. …”
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The Role of DJ-1 in the Glycation Process of Skin and Plasma Proteins in Mice Models by Abou Younes, Nour

“…Glycation was classified as an irreversible one-way reaction until the preexisting DJ-1 chaperone protein was identified as a deglycase protein. …”
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Performance analysis and iterative decoding of I-Q trellis space-time codes by Zummo, S.A.

“…I-Q trellis codes are known to increase the time diversity of coded systems. …”
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Human recombinant arginase I(Co)-PEG5000 [HuArgI(Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human acute myeloid leukemia cells by Bekdash, Amira

“…The four cell lines that were not rescued by l-citrulline did not express argininosuccinate synthetase-1, indicating complete arginine auxotrophy. Inhibition of autophagy increased cell sensitivity to HuArgI(Co)-PEG5000 demonstrating the protective role of autophagy following arginine deprivation. …”
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Phospho-MEK1/2 and uPAR Expression Determine Sensitivity of AML Blasts to a Urokinase-Activated Anthrax Lethal Toxin (PrAgU2/LF) 1 by Nasser, Selim

“…Cytotoxicity of PrAgU2/LF appeared to be nonapoptotic and was associated with MAPK activation and urokinase activity because all the PrAgU2/LF-sensitive cell lines showed both uPAR expression and high levels of MEK1/2 phosphorylation. Inhibition of uPAR or desensitization of cells to MEK1/2 inhibition blocked toxicity of PrAgU2/LF, indicating requirement for both uPAR expression and MAPK activation for activity. …”
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<i>Asterarcys quadricellulare</i> (Chlorophyceae) protects H9c2 cardiomyoblasts from H₂O₂-induced oxidative stress by Imen Saadaoui (14159025)

“…Furthermore, total caspase-3 was increased following treatment with the hexanoic extract, suggesting that <i>A. quadricellulare</i> also had anti-apoptotic properties. …”

Estimation of Virtual Trust on Driverless Cars using Type-1 Fuzzy logic by Mohamed Kayed Alhyasat, Khaled

“…Over a wireless network, these vehicles talk to one another. These vehicles use cameras and sensors to take note of their surroundings. …”
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Emtricitabine/rilpivirine/tenofovir disoproxil fumarate for the treatment of HIV-1 infection in adults by Kabbara, Wissam K.

“…Clinical trial reports were selected, extracted and analyzed to include relevant and recent ones. Selected English-language trials were limited to those with human subjects and included both safety and efficacy outcomes. …”
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The carboxy terminal coiled-coil modulates Orai1 internalization during meiosis by Rawad Hodeify (9592365)

“…SOCE is tightly regulated during meiosis, including internalization of the SOCE channel, Orai1. Orai1 is a four-pass membrane protein with cytosolic N- and C-termini. …”

Editorial: Dynamic Biomarkers of Response to Anti-Immune Checkpoint Inhibitors in Cancer by Said Dermime (79420)

“…In current clinical practice only PD-L1 expression in tumor tissues is used as predictive biomarker of response to PD-1 immune checkpoint blockade. …”

Guanine glycation repair by DJ-1/Park7 and its bacterial homologs by Richarme, Gilbert

“…DJ-1–depleted cells displayed increased levels of glycated DNA, DNA strand breaks, and phosphorylated p53. …”
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Higher serum leptin level in women than in nen with type 1 diabetes by Azar, Sami T.

“…In humans, serum leptin concentrations are increased in relation to increased body fat content. …”
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