Stress granules counteract senescence by sequestration of PAI‐1 by Amr Omer (18629374)

“…PAI‐1 localization to SGs increases the translocation of cyclin D1 to the nucleus, promotes RB phosphorylation, and maintains a proliferative, non‐senescent state. …”

Inositol 1,4,5-Trisphosphate Receptors in Hypertension by Ali H. Eid (5461829)

“…Evidence supports a role for vascular aging in the development of hypertension involving an impairment in endothelial function together with an alteration in vascular smooth muscle cells (VSMCs) calcium homeostasis leading to increased myogenic tone. Changes in free intracellular calcium levels ([Ca²⁺]_<em>i</em>) are mediated either by the influx of Ca²⁺ from the extracellular space or release of Ca²⁺ from intracellular stores, mainly the sarcoplasmic reticulum (SR). …”

Sanguinarine Induces Apoptosis Pathway in Multiple Myeloma Cell Lines via Inhibition of the JaK2/STAT3 Signaling by Sabah Akhtar (5809925)

“…In this study, we aimed to investigate the potential anti-proliferative and pro-apoptotic activities of SNG in a panel of MM cell lines (U266, IM9, MM1S, and RPMI-8226). SNG treatment of MM cells resulted in a dose-dependent decrease in cell viability through mitochondrial membrane potential loss and activation of caspase 3, 9, and cleavage of PARP. …”

Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway by Olfa Khalifa (10914452)

“…Additionally, after β-catenin silencing, OA treatment significantly increased the expression of nuclear transcription factors SREBP-1 and TCF4, whereas Ex-4 significantly decreased this upregulation. …”

Novel Thermo-Halotolerant Bacteria <i>Bacillus cabrialesii </i>Native to Qatar Desert: Enhancing Seedlings’ Growth, Halotolerance, and Antifungal Defense in Tomato by Fatma Masmoudi (16819554)

“…</i> cerasiforme and promote seeds germination and seedlings growth under saline conditions. …”

Which factor explains the life‐history of <i>Xanthium strumarium</i> L., an aggressive alien invasive plant species, along its altitudinal gradient? by Rafi Ullah (8146836)

“…The X. strumarium exhibits late vegetative and reproductive phenology at higher altitudes, enabling them to occupy an empty niche and benefit from decreased competition for resource acquisition. The lower altitude plants show a higher growth rate (stem size increase, number of leaves, and leaf area) due to the higher nutrient availability. …”

Flexural Response of Reinforced Concrete One-Way Slabs Embedded with Pet Bottles by Alhomsi, Chahed Abdulsatir

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Extended Preoperative Chemotherapy Does Not Improve Pathologic Response and Increases Postoperative Liver Insufficiency After Hepatic Resection for Colorectal Liver Metastases by Kishi, Yoji

“…Results Treatment consisting of ≥9 cycles was not associated with an increase in complete or major pathologic response (SD vs. …”
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An examination of how climate change could affect the future spread of <i>Fusarium</i> spp. around the world, using correlative models to model the changes by Muhammad Riaz Ejaz (20487191)

“…In this study, we hypothesize that crop diseases caused by <i>Fusarium</i> spp. will increase across all four corners of the world by 2050 and 2070 in response to future climate conditions. …”

Exploring the Dynamic Interplay of Deleterious Variants on the RAF1–RAP1A Binding in Cancer: Conformational Analysis, Binding Free Energy, and Essential Dynamics by Abbas Khan (5141000)

“…Integrated machine learning algorithms showed that among the 134 mutations reported for these 2 proteins, only 13 and 35 were classified as deleterious mutations in <i>RAF1</i> and <i>RAP1P</i>, respectively. Moreover, one mutation in RAF1 reported elevated levels of binding between <i>RAF1</i> and <i>RAP1P</i> while in <i>RAP1A</i>, 7 mutations were reported to increase the binding affinity. …”

Evaluating the invasive plant, <i>Prosopis juliflora</i> in the two initial growth stages as a potential candidate for heavy metal phytostabilization in metalliferous soil by Kamal Usman (11482990)

The effect of IL-1RA and IL-13 on cutaneous leishmaniasis in BALB/C mice as to hyperalgesia and the levels of IL-1b and IL-6. (c2005) by Hamdan, Hamdan Ghazi

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Structural and Biophysical Characterization of Stable Alpha-Synuclein Oligomers by Nishant Vaikath (3554687)

“…The secondary structure analysis revealed that only HNE and ONE oligomers contain β-sheet content. In the seeding assay, both DA and ONE oligomers significantly accelerated the aggregation. …”

Shear behaviour of one-way high strength plain and FRC slabs reinforced with basalt FRP bars by Abathar Al-Hamrani (16494884)

“…The main test variable was the BFRP longitudinal reinforcement ratio with two ratios of 0.792 % and 1.27 %. Also, two slabs were cast with basalt macro fibers (BMF) at a volume fraction of 0.75 % to explore the effect of the added fibers on the shear capacity of the tested one-way slabs. …”

iPads in the classroom: trials in a technical college in Qatar by Cheri Macleod (22401022)

“…Over 80% of students reported positively on the iPad as being “helpful” to “very helpful” for learning new things and course materials, for increasing their interaction with online course materials and getting course information and for exploring additional material related to course topics. …”

Adipocyte Enhancer-Binding Protein 1 (AEBP1) (a Novel Macrophage Proinflammatory Mediator) Overexpression Promotes and Ablation Attenuates Atherosclerosis in ApoE⁻′⁻ and LDLR⁻′⁻ Mi... by Bogachev, Oleg

“…Moreover, AEBP1 has been shown to promote macrophage inflammatory responsiveness by inducing nuclear factor (NF)-κB activity via IκBα downregulation. …”
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Morphological changes in amblyopic eyes in choriocapillaris and Sattler’s layer in comparison to healthy eyes, and in retinal nerve fiber layer in comparison to fellow eyes through... by Masri, Oussama Samer

“…Purpose Establishing the reliability of a new method to check the mean retinal and choroidal reflectivity and using it to find retinal and choroid changes in amblyopia. …”
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Para-Oleum 2 Fluid (POF): A Novel Magnetic Nanotechnology for Increased Oil Recovery from Contaminated Soil and Oil Spill Incidents by Aizere Andossova (23752959)

Abiotic stress applied to Tetraselmis subcordiformis reveals enhanced metabolic responses and increased production of Omega-3 fatty acids: A Metabolomic approach by Imen, Saadaoui

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ROS-Mediated Autophagic Death in Glioblastoma Cells Upon Treatment by Human Recombinant Arginase I (Co)- PEG5000 [HuArgI (Co)-PEG5000] by Abdel Khalek, Maya

“…In this study, we examine the mechanism of HuArgI (Co)-PEG5000-induced cell death in both partially and completely auxotrophic GBM cell lines. …”
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