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Positive regulation of oxidative phosphorylation by nuclear myosin 1 protects cells from metabolic reprogramming and tumorigenesis in mice
Published 2023“…<p dir="ltr">Metabolic reprogramming is one of the hallmarks of tumorigenesis. Here, we show that nuclear myosin 1 (NM1) serves as a key regulator of cellular metabolism. …”
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222
Concentrated photovoltaic thermal (CPVT) solar collector systems: Part I - Fundamentals, design considerations and current technologies
Published 2015“…Concentrated photovoltaic thermal (CPVT) solar collectors have been gaining ever-increasing attention from the scientific community and industrial developers due to their promising potential to pave the way for the penetration of solar energy into modern day power generation technologies. …”
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223
C1 neurons excite locus coeruleus and A5 noradrenergic neurons along with sympathetic outflow in rats
Published 2012“…In additional rats, the retrotrap ezoid nucleus region wasdestroyed with substance P–saporin prior to lentivirus injection into the rostral ventrolateralmedulla, increasing the propor tion of C1 ChR2-expressing neurons (83%). …”
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224
SIRT1 promotes lipid metabolism and mitochondrial biogenesis in adipocytes and coordinates adipogenesis by targeting key enzymatic pathways
Published 2021“…Supplementing preadipocytes with the NAD+ booster nicotinamide mononucleotide (NMN) during differentiation increased expression levels of leptin, SIRT1, and PGC-1α and its transcriptional targets, and reduced levels of pro-fibrotic collagens (Col6A1 and Col6A3) in a SIRT1-dependent manner. …”
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225
Controversy and Debate: Questionable utility of the relative risk in clinical research: Paper 1: A call for change to practice
Published 2020“…Methods We used mathematical derivation to determine if the RR is a measure of effect magnitude alone (i.e., a larger absolute value always indicating a stronger effect) or not. …”
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226
Controversy and Debate: Questionable utility of the relative risk in clinical research: Paper 1: A call for change to practice
Published 2020“…</p><h3>Methods</h3><p dir="ltr">We used mathematical derivation to determine if the RR is a measure of effect magnitude alone (i.e., a larger absolute value always indicating a stronger effect) or not. …”
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227
Characterisation of Pga1, a putative Candida albicans cell wall protein necessary for proper adhesion and biofilm formation
Published 2015“…It was observed that the mutant strain showed less oxidative stress tolerance and an increased susceptibility to calcofluor white, a cell surface disrupting agent that inhibits chitin fibre assembly which translated as a 40% decrease in cell wall chitin content. …”
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228
Layered homologous compounds (ZnO)<sub><em>k</em></sub>In<sub>2</sub>O<sub>3</sub> (<i>k</i> = 3, 5, and 7) as novel photocatalysts for visible-light-driven photocatalytic degradat...
Published 2024“…UV–vis spectroscopy revealed the band gap widening with increasing ‘<i>k</i>’, while IZO-5 and IZO-7 exhibit lower PL emissions in the visible range. …”
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A SENSITIVE APPROACH TO DETERMINE THE HEALTH STATUS OF I-BEAMS BY MEASURING ITS NONLINEARITY THROUGH THE USE OF RAYLEIGH WAVES
Published 2019“…The present study focusses on evaluating the health status of a 1018 steel I-beam using a new nonlinearity parameter defined for Rayleigh waves. …”
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231
PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
Published 2019“…Understanding the mechanisms behind this PD-L1 overexpression in cancer stem cells is critical for developing more effective strategies for preventing immune evasion and increasing the efficacy of anti-PD-1/PD-L1 therapy. …”
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232
Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…Mice with ectopic expression of uncoupling protein-1 (UCP1) in skeletal muscle exhibit a healthy aging phenotype with increased longevity and resistance to impaired metabolic health. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…<p dir="ltr">Mice with ectopic expression of uncoupling protein-1 (UCP1) in skeletal muscle exhibit a healthy aging phenotype with increased longevity and resistance to impaired metabolic health. …”
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The Candida albicans Dse1 Protein Is Essential and Plays a Role in Cell Wall Rigidity, Biofilm Formation, and Virulence
Published 2011“…The fungal pathogen Candida albicans is one of the leading causative agents of death in immunocompromised individuals. …”
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235
The contribution of autophagy in glioblastoma multiforme cells treated with human recombinant arginase I-induced arginine deprivation. (c2018)
Published 2018“…All this results in a poor survival rate in GBM patients, which doesn’t exceed 1 year. Therefore, there is a need for more selective and effective approaches, such as the use of human recombinant arginase I to selectively target cells that are auxotrophic to arginine. …”
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Targeting arginine auxotrophy in pancreatic cancer cells using human recombinant arginase I-induced arginine deprivation. (c2017)
Published 2017“…Pancreatic cancer (PC) is a highly aggressive solid malignancy with no efficient therapy. It is one of the deadliest cancer types since its mortality rate per year is nearly equal to its incidence rate. …”
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237
The Stakeholders’ Perceptions about the Effectiveness of iPads Integrations in Third Grade English Classes in a Private School in Sharjah, UAE
Published 2023“…The purpose of this study is to examine the attitude of parents, teachers, and leaders of the iPad’s integrations in third grade English classes in one of the private schools in Sharjah. …”
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Transforming growth factor-β1 and phosphatases modulate COX-2 protein expression and TAU phosphorylation in cultured immortalized podocytes
Published 2018“…Interestingly, podocyte co-incubated with TGF-β1, high glucose and/or PGE2 showed strong increase in p38 MAPK and AKT phosphorylation as well as COX- 2 protein expression levels. …”
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Catalytic CO<sub>2</sub> conversion to C1 value-added products: Review on latest catalytic and process developments
Published 2023“…<p dir="ltr">With the increase in CO<sub>2</sub> emissions in the last decades, CO<sub>2</sub> capture and storage and CO<sub>2</sub> capture and utilization technologies have been interesting topics in literature and industry. …”
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Software-Defined-Networking-Based One-versus-Rest Strategy for Detecting and Mitigating Distributed Denial-of-Service Attacks in Smart Home Internet of Things Devices
Published 2024“…These are considered to be an increasing trend, and it will be a major challenge to reduce risk, especially in the future. …”