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241
Controversy and Debate: Questionable utility of the relative risk in clinical research: Paper 1: A call for change to practice
منشور في 2020"…</p><h3>Methods</h3><p dir="ltr">We used mathematical derivation to determine if the RR is a measure of effect magnitude alone (i.e., a larger absolute value always indicating a stronger effect) or not. …"
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242
Dynamic Properties of Water Confined in Graphene-Based Membrane: A Classical Molecular Dynamics Simulation Study
منشور في 2019"…We also calculated the reorientational correlation time of the water molecules, and we found that the rotational motion of confined water inside the membrane is anisotropic and the reorientational correlation time of confined water is slower than that of bulk water. …"
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243
Layered homologous compounds (ZnO)<sub><em>k</em></sub>In<sub>2</sub>O<sub>3</sub> (<i>k</i> = 3, 5, and 7) as novel photocatalysts for visible-light-driven photocatalytic degradat...
منشور في 2024"…UV–vis spectroscopy revealed the band gap widening with increasing ‘<i>k</i>’, while IZO-5 and IZO-7 exhibit lower PL emissions in the visible range. …"
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244
The contribution of autophagy in glioblastoma multiforme cells treated with human recombinant arginase I-induced arginine deprivation. (c2018)
منشور في 2018"…The activation of LC3-I peaked in control conditions (chloroquine treatment), considerably decreased in cells treated with the highest arginase concentration, then increased again in cells treated with both arginase at its highest concentration and chloroquine. mTOR is active in control cells, while at highest arginase concentration there is an inactivation of mTOR resulting in the activation of autophagy. …"
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masterThesis -
245
A SENSITIVE APPROACH TO DETERMINE THE HEALTH STATUS OF I-BEAMS BY MEASURING ITS NONLINEARITY THROUGH THE USE OF RAYLEIGH WAVES
منشور في 2019"…The present study focusses on evaluating the health status of a 1018 steel I-beam using a new nonlinearity parameter defined for Rayleigh waves. …"
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246
Targeting arginine auxotrophy in pancreatic cancer cells using human recombinant arginase I-induced arginine deprivation. (c2017)
منشور في 2017"…Pancreatic cancer (PC) is a highly aggressive solid malignancy with no efficient therapy. It is one of the deadliest cancer types since its mortality rate per year is nearly equal to its incidence rate. …"
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masterThesis -
247
PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
منشور في 2019"…Understanding the mechanisms behind this PD-L1 overexpression in cancer stem cells is critical for developing more effective strategies for preventing immune evasion and increasing the efficacy of anti-PD-1/PD-L1 therapy. …"
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248
Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…Mice with ectopic expression of uncoupling protein-1 (UCP1) in skeletal muscle exhibit a healthy aging phenotype with increased longevity and resistance to impaired metabolic health. …"
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article -
249
Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…<p dir="ltr">Mice with ectopic expression of uncoupling protein-1 (UCP1) in skeletal muscle exhibit a healthy aging phenotype with increased longevity and resistance to impaired metabolic health. …"
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250
Characterisation of Pga1, a putative Candida albicans cell wall protein necessary for proper adhesion and biofilm formation
منشور في 2015"…Many of these factors are glycosylphosphatidylinositol-anchored cell surface antigenic determinant proteins. Pga1 is one such protein shown to be upregulated during cell wall regeneration. …"
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article -
251
The Candida albicans Dse1 Protein Is Essential and Plays a Role in Cell Wall Rigidity, Biofilm Formation, and Virulence
منشور في 2011"…The fungal pathogen Candida albicans is one of the leading causative agents of death in immunocompromised individuals. …"
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article -
252
Health in times of uncertainty in the eastern Mediterranean region, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013
منشور في 2016"…However, diarrhoeal diseases were the leading cause of death in Somalia (186·7 deaths per 100 000 people) in 2013, which decreased by 26·9% since 1990. …"
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article -
253
The Stakeholders’ Perceptions about the Effectiveness of iPads Integrations in Third Grade English Classes in a Private School in Sharjah, UAE
منشور في 2023"…The purpose of this study is to examine the attitude of parents, teachers, and leaders of the iPad’s integrations in third grade English classes in one of the private schools in Sharjah. …"
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254
The Effect of Experimental Recuperative and Appetitive Post-lunch Nap Opportunities, With or Without Caffeine, on Mood and Reaction Time in Highly Trained Athletes
منشور في 2021"…<h3>Purpose</h3><p dir="ltr">To investigate the effects of placebo (PLA), 20 min nap opportunity (N20), 5mg·kg<sup>−1</sup> of caffeine (CAF), and their combination (CAF+N20) on sleepiness, mood and reaction-time after partial sleep deprivation (PSD; 04h30 of time in bed; <i>study 1</i>) or after normal sleep night (NSN; 08h30 of time in bed; <i>study 2</i>).…"
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255
Transforming growth factor-β1 and phosphatases modulate COX-2 protein expression and TAU phosphorylation in cultured immortalized podocytes
منشور في 2018"…Interestingly, podocyte co-incubated with TGF-β1, high glucose and/or PGE2 showed strong increase in p38 MAPK and AKT phosphorylation as well as COX- 2 protein expression levels. …"
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article -
256
Catalytic CO<sub>2</sub> conversion to C1 value-added products: Review on latest catalytic and process developments
منشور في 2023"…<p dir="ltr">With the increase in CO<sub>2</sub> emissions in the last decades, CO<sub>2</sub> capture and storage and CO<sub>2</sub> capture and utilization technologies have been interesting topics in literature and industry. …"
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257
Software-Defined-Networking-Based One-versus-Rest Strategy for Detecting and Mitigating Distributed Denial-of-Service Attacks in Smart Home Internet of Things Devices
منشور في 2024"…These are considered to be an increasing trend, and it will be a major challenge to reduce risk, especially in the future. …"
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258
Inequalities in cardiovascular disease among elderly Indians: A gender perspective analysis using LASI wave-I (2017-18)
منشور في 2024"…Women have a 33% higher likelihood of CVD compared to men (OR: 1.33; 95% CI: 1.25-1.42). Lack of education also confers a lower risk, more pronounced in women with no schooling (OR: 0.81; 95% CI: 0.7-0.94) compared to men (OR: 0.52; 95% CI: 0.47-0.58). …"
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259
Empagliflozin inhibits angiotensin II-induced hypertrophy in H9c2 cardiomyoblasts through inhibition of NHE1 expression
منشور في 2022"…Our study demonstrated that ANG-induced hypertrophy of H9c2 cardiomyoblasts is accompanied with increased SGLT-1 and NHE1 protein expression, an effect which is prevented in the presence of EMPA. …"
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260
Inhibiting HSP90 changes the expression pattern of PINK1 and BNIP3 and induces oxidative stress in colon cancer cells
منشور في 2025"…</p><h3>Conclusion</h3><p dir="ltr">Targeting HSP90 in colon cancer cells disrupts their survival by decreasing PINK1 and increasing BNIP3, which activates oxidative and endoplasmic reticulum stress, ultimately triggering apoptosis.…"