Hexokinase-2-Linked Glycolytic Overload and Unscheduled Glycolysis—Driver of Insulin Resistance and Development of Vascular Complications of Diabetes by Naila Rabbani (291722)

“…This may explain the increased glucose disposal by skeletal uptake in the fasting phase in patients with type 2 diabetes mellitus, compared to healthy controls, and the presence of insulin resistance in patients with type 1 diabetes mellitus. …”

Targeting human acute myeloid leukemia cells using human recombinant arginase I (Co) - PEG5000 [HuArgl (Co) - PEG5000] - induced arginine depletion. (c2013) by Tanios, Rita Farid

Get full text
Get full text

The effect of Ramadan focused education on patients with type 2 diabetes: A systematic review and meta-analysis by Hoda Gad (6470522)

“…Quality assessment was done using the ROBINS-I and Cochrane tools for risk of bias and analyses were performed using RevMan version 5.1.…”

Analysis of Serum Advanced Glycation Endproducts Reveals Methylglyoxal-Derived Advanced Glycation MG-H1 Free Adduct Is a Risk Marker in Non-Diabetic and Diabetic Chronic Kidney Dis... by Naila Rabbani (291722)

“…MG-H1 Glomerular filtration flux was increased 5-fold in diabetes, likely reflecting increased methylglyoxal glycation status. …”

In vivo assessment of the nephrotoxic effects of the synthetic cannabinoid AB-FUBINACA by Ayman Alzu’bi (13162392)

“…These findings were also correlated with increased expression of major apoptosis regulatory markers (Bax, caspase-9, caspase-3) and reduced expression of mitochondrial complexes I, III, and IV.…”

Monitoring the Athlete Match Response: Can External Load Variables Predict Post-match Acute and Residual Fatigue in Soccer? A Systematic Review with Meta-analysis by Karim Hader (2548618)

“…For every 100-m run above 5.5 m·s⁻¹, CK activity measured 24 h post-match increased by 30% and CMJPPO decreased by 0.5%. …”

Domain Walls Conductivity in Hybrid Organometallic Perovskites and Their Essential Role in CH₃NH₃PbI₃Solar Cell High Performance by Sergey N. Rashkeev (19686943)

“…We find that due to the charge carrier accumulation, the static conductivity may drastically increase at the domain wall by 3 – 4 orders of magnitude in comparison with conductivity through the bulk of the material. …”

An overview of diabetes mellitus in pregnant women with obesity by Mohammed, Bashir

“…Rates of obesity are increasing world-wide with an estimated 1billion people projected to be obese by 2030 if current trends remain unchanged. …”
Get full text
Get full text
Get full text

Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis by Meritxell Espino‐Guarch (22565774)

“…Ex vivo incubation of LAT2KO muscle with rapamycin recovered proteolysis function, demonstrating a mTORC1‐dependent pathway. Decreased proteolysis in LAT2KO animals was associated with increased mTORC1 translocation to the lysosome (mTORC1‐Lamp1 colocalization in fasted LAT2KO muscles was 1.23‐fold, <i>p</i> < 0.0001). …”

Deletion of TRPC6, an Autism Risk Gene, Induces Hyperexcitability in Cortical Neurons Derived from Human Pluripotent Stem Cells by Kyung Chul Shin (13913556)

The Effect of Atorvastatin (and Subsequent Metformin) on Adipose Tissue Acylation-Stimulatory-Protein Concentration and Inflammatory Biomarkers in Overweight/Obese Women With Polyc... by Thozhukat Sathyapalan (704787)

“…</p><h3>Results</h3><p dir="ltr">There was significant reduction in ASP (156.7 ± 16.2 vs. 124.4 ± 14.8 ng/ml p <0.01), IL-6 (1.48 ± 0.29 vs.0.73 ± 0.34 pg/ml p = 0.01) and MCP-1 (30.4 ± 4.2 vs. 23.0 ± 4.5 pg/ml p = 0.02) after 12 weeks of atorvastatin that was maintained subsequently with 12 weeks treatment with metformin. …”

Prostaglandin E2 regulates the level and stability of cyclooxygenase-2 mRNA through activation of p38 mitogen-activated protein kinase in interleukin-1β-treated human synovial fibr... by Faour, Wissam

“…Deletion analysis using transfected chimeric luciferase-COX-2 mRNA 3′-untranslated region reporter constructs revealed that IL-1β increased reporter gene mRNA stability and translation via AU-containing distal regions of the untranslated region. …”
Get full text
Get full text
Get full text

Cumulative Incidence of Venous Thromboembolic Events In-Hospital, and at 1, 3, 6, and 12 Months After Metabolic and Bariatric Surgery: Systematic Review of 87 Studies and Meta-anal... by Walid El Ansari (93732)

“…Pooled in-hospital VTE of mainly laparoscopic studies = 0.15% (95% CI = 0.13–0.18%); pooled cumulative incidence increased to 0.50% (95% CI = 0.33–0.70%); 0.51% (95% CI = 0.38–0.65%); 0.72% (95% CI = 0.13–1.52%); 0.78% (95% CI = 0–3.49%) at 30 days and 3, 6, and 12 months, respectively. …”

Experimental and modeling analysis of p-type Bi₀.₄Sb₁.₆Te₃ and graphene nanocomposites by Aicha S. Lemine (17148352)

“…The GNS addition has increased the output power of pristine Bi_0.4Sb_1.6Te₃ by 7%, leading to comparable TE performance to other simulated Bi₂Te₃ systems.…”

RFX3 is essential for the generation of functional human pancreatic islets from stem cells by Bushra Memon (4792767)

“…This was supported by our findings of high EC marker expression levels in <i>RFX3</i> KO EPs and islets. In addition, RFX3 loss led to smaller islet organoids, elevated thioredoxin-interacting protein levels and increased apoptosis in EPs and islets. …”

Effective non-intrusive load monitoring of buildings based on a novel multi-descriptor fusion with dimensionality reduction by Yassine Himeur (14158821)

“…This paper presents an efficient non-intrusive load monitoring framework that consists of the following main components: (i) a novel fusion of multiple time-domain features is proposed to extract appliance fingerprints; (ii) a dimensionality reduction scheme is introduced to be applied to the fused time-domain features, which relies on fuzzy-neighbors preserving analysis based QR-decomposition. …”

Hydrogen bonding: a mechanism for tuning electronic and optical properties of hybrid organic–inorganic frameworks by Fedwa El-Mellouhi (2011099)

“…Considering hybrid framework materials with different structural ordering containing protonated sulfonium cation H₃S⁺ and electronegative halogen anions (I⁻, Br⁻, Cl⁻ and F⁻), we found that hydrogen bonding increases the structural stability of the material and may be used for tuning electronic states near the bandgap. …”

Revisiting high-density lipoprotein cholesterol in cardiovascular disease: Is too much of a good thing always a good thing? by Mohammad Al Zein (20090700)

Genetic Polymorphism Effect on Warfarin–Rifampin Interaction: A Case Report and Review of Literature by Muhammad Salem (8979428)

“…Over six weeks, the daily warfarin dose was increased from 3 to 10 mg to attain three consecutive in-clinic therapeutic INRs. …”

Clinical and biochemical determinants of length of stay, readmission and recurrence in patients admitted with diabetic ketoacidosis by Fateen Ata (12217764)

“…The median LOS was 2.6 days (IQR 1.1–4.8), and the median DKA resolution time was 18 h (10.5–29). …”