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1061
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1062
Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels
Published 2024“…Notably, there was an increase in sphingomyelin (SM 34:2) levels (estimate 0.23, <i>p</i> ≤ 0.001), which are critical for cell membrane structure and signalling. Additionally, a decrease in glycochenodeoxycholic acid levels was also triggered by treatment with AuNPs, suggesting modulation of bile acid metabolism with potential effects on lipid homeostasis. …”
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1063
Immunomodulatory effects of tumor Lactate Dehydrogenase C (LDHC) in breast cancer
Published 2025“…Following <i>LDHC</i> knockdown, we observed an increase in the secretion of tumor-derived pro-inflammatory cytokines (IFN-γ, GM-CSF, MCP-1, CXCL1), a decrease in the soluble levels of tumor-derived immunosuppressive factors (IL-6, Gal-9) and reduced tumor cell surface PD-L1 expression. …”
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1064
Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes
Published 2023“…Similarly, KO 47 mice also showed a slower rate of glucose clearance in GTT that was consistent with decreased mRNA expression of the GLUT4 gene in WAT but not in the muscle. …”
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1065
Understanding the phenomenon of saltwater intrusion sourced from desalination plants at coastal aquifers
Published 2023“…For the two-region model, dispersion coefficients were well defined and remained unchanged from the convective–diffusion equation for potassium ions but decreased for bromide ions. Retardation factors for bromide ions were approximately the same, but those for potassium ions, though > 1, were poorly defined. …”
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1066
Fixed Shading Scenarios to Optimize Lighting Performance and Energy Efficiency in Office Buildings Case Study of Dubai Design District
Published 2021“…The second-best method was the Horizontal Louvers, where it achieved a reduction in energy consumption by 7.7% compared to the base case, and in daylight, it achieved a decrease of 50% in Both selected months. …”
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1067
Wild carrot pentane-based fractions suppress proliferation of human HaCaT keratinocytes and protect against chemically-induced skin cancer
Published 2017“…Treatment of HaCaT-ras A5 and HaCaT-ras II4 cells with F2 fraction resulted in the accumulation of cells in the sub-G1 apoptotic phase and decreased the population of cells in the S and G2/M phases. …”
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1068
Assessment of resin systems as solution for well integrity challenge in carbonate reservoirs
Published 2023“…Additionally, the transit time showed a 26–42% range decrease in the travel period, indicating that the cement was stronger under increased pressure and temperature. …”
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1069
Effect of structural remodeling (retraction and recoil) of the pipeline embolization device on aneurysm occlusion rate
Published 2014“…RESULTS: Structural changes of the device have been observed, and it was found that the Pipeline Embolization Device influences the vessel curvature in some cases. On average, it increases its diameter by 0.23 mm and decreases its length by 2.88 mm within 6 months of initial deployment. …”
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1070
Waterpipe Tobacco Smoke Nicotine Mediates Resilience to Chronic Stress by Activating BDNF Signaling
Published 2020“…The purpose of this study was to investigate how nicotine in the context of waterpipe tobacco smoking (WTS) affects depression and anxiety-like behaviors associated with chronic social defeat stress (CSDS) in a male C57BL/6J animal model. The mice were exposed to WTS or received intraperitoneal injections of nicotine for thirty days, before being subjected to CSDS for ten days. …”
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masterThesis -
1071
Cost-benefit analysis for the installation of cogeneration CSP technology in Cyprus
Published 2013“…The results indicate that the electricity unit cost or benefit for both cases of electricity purchasing tariff are decreased or increased with the increase of the capacity factor and the capacity size of the plant. …”
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1072
The ortholog of human ssDNA-binding protein SSBP3 influences neurodevelopment and autism-like behaviors in <i>Drosophila melanogaster</i>
Published 2023“…Moreover, Ssdp overexpression led to differential changes in synaptic density in specific brain regions. We observed decreased levels of armadillo in the heads of Ssdp overexpressing flies, as well as a decrease in armadillo and wingless expression in the larval wing discs, implicating the involvement of the canonical Wnt signaling pathway in Ssdp functionality. …”
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1073
The effect of Hydrogen Peroxide treatments on dental enamel porosity and protein structure and its long-term implications on tooth hardness and optical properties
Published 2025“…ResultsShade analysis revealed that, in the short term, HP treatment significantly increased lightness and Hue and decreased chroma compared to DW (p < 0.05); however, 1 week after treatment some of the initial gains in tooth lightness were partially lost. …”
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1074
Autophagy Mediates the Effects of Physical Exercise on Learning and Memory through Activation of Hippocampal BDNF
Published 2020“…These positive outcomes are mediated through the induction of the expression of a growth factor, brain derived neurotrophic factor (BDNF), in the hippocampus. …”
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masterThesis -
1075
An empirical study on measuring operating efficiency and revenue of real estate assets in the UAE using data envelopment analysis
Published 2022“…This method could produce a more informed and balanced approach to performance measurement. …”
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1076
Location matters: spatial dynamics of tumor-infiltrating T cell subsets is prognostic in colon cancer
Published 2024“…We demonstrated an increase in immune cell density and a decrease in the distance of CD3<sup>+</sup>CD8<sup>+</sup> T cells to the nearest tumor cell, in the immune active, ICR High, immune subtypes. …”
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1077
Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1<sup>+</sup>/NKX6.1<sup>+</sup> progenitors
Published 2024“…Upon differentiating iPSCs lacking RFX6 into pancreatic islets, a significant decrease in PDX1 expression at the PF stage was observed, although this did not affect PPs co-expressing PDX1 and NKX6.1. …”
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1078
DNA methylation signature in peripheral blood reveals distinct characteristics of human X chromosome numerical aberrations
Published 2015“…The X inactivation process appears to be less effective in Klinefelter syndrome as methylation on the X was decreased compared to normal female samples. In a large number of individuals, we verified several loci by pyrosequencing and observed only weak inter-loci correlations between the verified regions. …”
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1079
Impact of the positive pressure valve on vascular access device occlusions and bloodstream infections
Published 2009“…These types of devices have been shown to significantly decrease VAD occlusion rates by 8.2%, when compared to a standard connector device (Jacobs et al., 2004). …”
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1080
Nebulized fentanyl for respiratory symptoms in patients with COVID-19 (ventanyl trial)
Published 2022“…The proposed theory behind that was that fentanyl decreased the rate of spontaneous respiratory rate, diminished the brain stem chemoreceptor response to hypoxia and hypercarbia, in addition to exhibiting a modulating effect on the brain stem. …”