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81
A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
Published 2025“…Gaussian accelerated molecular dynamics (GaMD) simulations of the predicted alpha-helical synthetic Mpro cleavage sequences revealed a dynamic nature of the cleavage sequences, which is critical for their efficient cleavage, and a relatively short end-to-end distances, which is required for high BRET. …”
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82
Inhibiting HSP90 changes the expression pattern of PINK1 and BNIP3 and induces oxidative stress in colon cancer cells
Published 2025“…Cancer cells utilize HSP90 in order to prolong their survival, thus they tend to overexpress it. Based on its importance for cancer cells, we aim to investigate the molecular mechanisms that link HSP90 inhibition in colon cancer cells with oxidative stress and mitochondrial stress—related regulators.…”
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83
Water Footprint Assessment and Virtual Water Trade in the Globally Most Water-Stressed Country, Qatar
Published 2023“…The virtual water exports gradually decreased over the years with the most notable decrease in 2018 following Qatar’s blockade. …”
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84
Portfolio Selection Problem Using CVaR Risk Measures Equipped with DEA, PSO, and ICA Algorithms
Published 2022“…It was found that when solving the Mean-CVaR model with evolutionary algorithms, the risk decreased. …”
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85
Which factor explains the life‐history of <i>Xanthium strumarium</i> L., an aggressive alien invasive plant species, along its altitudinal gradient?
Published 2022“…Among climatic variables, mean yearly temperature, mean annual yearly humidity, and mean day length in hours, while in soil variables, organic matter and nitrogen percentage significantly affect the phenological and morphological stages. …”
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86
Land surface temperature responses to land use dynamics in urban areas of Doha, Qatar
Published 2024“…The LST data derived from remote sensing sources demonstrates an upward trend for summer and a contrasting trend for winter. Specifically, the mean summer LST increases by 7.64 °C (0.34 °C annually), and the mean winter LST decreases by 4.87 °C (0.22 °C annually). …”
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87
Mental health, burnout and resilience in community pharmacists during the COVID-19 pandemic: A cross-sectional study
Published 2022“…Participants had shown moderate resilience (mean score: 27.64 (SD = 8.31)) and their mean score fear of COVID19 was 15.67 (SD = 6.54). …”
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88
Excess pCO<sub>2</sub> and carbonate system geochemistry in surface seawater of the exclusive economic zone of Qatar (Arabian Gulf)
Published 2022“…CO<sub>2</sub> is lost from the Gulf due to gas exchange, decreasing DIC, and reducing pCO<sub>2</sub> to 464 μatm, similar to that observed. …”
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89
Changing life expectancy in European countries 1990–2021: a subanalysis of causes and risk factors from the Global Burden of Disease Study 2021
Published 2025“…In 2019–21, there was an overall decrease in mean annual life expectancy across all countries (overall mean –0·18 years [95% UI –0·22 to –0·13]), with all countries having an absolute fall in life expectancy except for Ireland, Iceland, Sweden, Norway, and Denmark, which showed marginal improvement in life expectancy, and Belgium, which showed no change in life expectancy. …”
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90
Impact of staying at home measures during COVID-19 pandemic on the lifestyle of Qatar’s population: Perceived changes in diet, physical activity, and body weight
Published 2021“…Participants reported increased sitting/reclining time (1.94 h/day mean increase), screen times (2.05 h/day mean increase) with p < 0.001, and decreased exercise time (0.11 h/day mean reduction) with p < 0.001. …”
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91
Land surface temperature responses to land use dynamics in urban areas of Doha, Qatar
Published 2024“…The LST data derived from remote sensing sources demonstrates an upward trend for summer and a contrasting trend for winter. Specifically, the mean summer LST increases by 7.64 °C (0.34 °C annually), and the mean winter LST decreases by 4.87 °C (0.22 °C annually). …”
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92
Empirical evaluation of change in crash risk due to lane marking reallocation: A case study in Kochi City, Japan
Published 2023“…In addition, the results indicate that the PICUD value tends to decrease (i.e., the crash risk tends to increase) with increasing speed of the following vehicle relative to the leading vehicle. …”
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93
3D FEM Model on the Parameters’ Influence of EPB-TBM on Settlements of Single and Twin Metro Tunnels During Construction
Published 2022“…The maximum settlements occurred at the end of the shield tail and it was higher in the single tunnel. …”
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94
Functionalization of reverse osmosis membrane with graphene oxide to reduce both membrane scaling and biofouling
Published 2020“…Results indicated that the permeate flux was reduced by only 15% at the end of the scaling experiment as opposed to the bared RO membrane which faced up to 22% decline in flux. …”
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95
Aorta deformation linked to heart disease
Published 2015“…Normally this stiffening is associated with increased morbidity in patients with hypertension, diabetes, and end-stage kidney disease, but whether this is also true of HCM is still not clear. …”
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96
Use of Carbide Derived Carbon in Water Treatment and Thermal Fluids Applications
Published 2021“…Water scarcity is a global issue due to the increasing demand and consumption of natural water resources, which are under stress from; a growing human population, decreasing ground water tables and precipitation, and increasing agriculture, industrialization and urbanization. …”
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97
Psychological and Coping Strategies Related to Home Isolation and Social Distancing in Children and Adolescents During the COVID-19 Pandemic: Cross-sectional Study
Published 2021“…Higher levels of anger, depression, and general anxiety were prevalent among 1.3% (n=84), 3.9% (n=260), and 1.6% (n=104) of participants, respectively. The mean score for the emotional constructs anger and depression decreased with increased compliance with regulations (<i>P</i>=.04 and <i>P</i>=.11, respectively). …”
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98
Writing and publishing language studies in the Arab region [Khitabaat Journal]
Published 2024“…Klein starts from an implicit assumption that writing and reading are individual activities and suggests that (individual) writers must decrease their production to enable their (individual) readers to read it. …”
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99
Non-Isolated DC–DC Power Converter With High Gain and Inverting Capability
Published 2021“…To reduce the ripple in the input current with simultaneous decreasing the input current ripple, a novel current fed interleaved high gain converter is proposed by utilizing the interleaved front-end structure and Cockcroft Walton (CW)-Voltage Multiplier (VM). …”
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100
Impaired Liver Size and Compromised Neurobehavioral Activity are Elicited by Chitosan Nanoparticles in the Zebrafish Embryo Model
Published 2019“…Although no single sign of cardiotoxicity was observed upon exposure to 200 mg/L of ChNPs, as judged by heartbeat rate, the corrected QT interval (QTc, which measures the time between the start of the Q wave and the end of the T wave in the heart's electrical cycle), maximum cardiac arrest, and ejection fraction assays, the same dosage elicited the impairment of both liver size (decreased liver size, but without steatosis and lipid yolk retention) and neurobehavioral activity (increased movement under different light conditions). …”