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561
Small molecule inhibitors of α-synuclein oligomers identified by targeting early dopamine-mediated motor impairment in C. elegans
Published 2021“…<h3>Background</h3><p dir="ltr">Parkinson’s disease is a disabling neurodegenerative movement disorder characterized by dopaminergic neuron loss induced by α-synuclein oligomers. There is an urgent need for disease-modifying therapies for Parkinson’s disease, but drug discovery is challenged by lack of in vivo models that recapitulate early stages of neurodegeneration. …”
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562
Optimal management, prevalence, and clinical behavior of saddle pulmonary embolism: A systematic review and meta-analysis
Published 2022“…Female sex (61.5 % vs. 41.3 %, p = 0.019), hypoxemia (90 % vs. 59.2 %, p < 0.001), massive PE features (89.7 % vs. 30.1 %, p < 0.001), associated chronic kidney disease (CKD) (10.3 % vs. 1.4 %, p = 0.002), and the need for mechanical ventilation (28.2 % vs. 13.1 %, p = 0.02) were significantly associated with increased mortality. …”
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563
Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 co...
Published 2024“…Globally between 2010 and 2021, the age-standardised DALY rates for HIV/AIDS decreased by 47·8% (43·3–51·7) and for diarrhoeal diseases decreased by 47·0% (39·9–52·9). …”
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A systematic review on sequence-to-sequence learning with neural network and its models
Published 2021“…The evidence we adopted in conducting this survey included utilizing the examination inquiries or research questions to determine keywords, which were used to search for bits of peer-reviewed papers, articles, or books at scholastic directories. …”
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568
Distribution of Doxorubicin in Rats Undergoing Ultrasonic Drug Delivery
Published 2010Get full text
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569
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570
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571
Bulk passivation of perovskite films utilizing halide anion ionic liquids
Published 2023Get full text
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572
TCAD Simulation and Analysis of Selective Buried Oxide MOSFET Dynamic Power
Published 2019Get full text
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579
Environmental Footprint and Economics of a Full-Scale 3D-Printed House
Published 2021Get full text
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580
The burden of unintentional drowning: global, regional and national estimates of mortality from the Global Burden of Disease 2017 Study
Published 2020“…The results reinforce the need for continued and improved policy, prevention and research efforts, with a focus on low- and middle-income countries.…”