Proteomic analyses of the cell walls of candida albicans PGA1 and PIR32 null mutants. (c2017) حسب Khoury, Pamela Milad El

"…The pir32 null strain on the other hand showed more pronounced phenotypes such as hyperfilamentation ability, and increased resistance to oxidative stress in part due to a two fold increase in chitin deposition. …"
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NKX6.1 transcription factor: a crucial regulator of pancreatic β cell development, identity, and proliferation حسب Idil I. Aigha (14913774)

"…The importance of NKX6.1 as a crucial regulator in MPC specification into functional β cells directs attentions to further investigating its mechanism and enhancing NKX6.1 expression as a means to increase β cell function and mass. …"

Unleashing the immune response to NY-ESO-1 cancer testis antigen as a potential target for cancer immunotherapy حسب Afsheen Raza (492657)

"…We propose that combination therapy to increase the efficacy of NY-ESO-1 specific immunotherapeutic interventions should be explored to unleash the immune response against NY-ESO-1 expressing tumors.…"

Prehospital Intervals and In-Hospital Trauma Mortality: A Retrospective Study from a Level I Trauma Center حسب Hassan Al-Thani (440106)

"…</p><h3>Results</h3><p dir="ltr">A total of 1,455 patients were included, of which nearly one-quarter of patients required urgent and life-saving care at a trauma center (T1 activations). …"

High fractional excretion of glycation adducts is associated with subsequent early decline in renal function in type 1 diabetes حسب Bruce A. Perkins (8630269)

"…<div><p>Increased protein glycation, oxidation and nitration is linked to the development of diabetic nephropathy. …"

Positive regulation of oxidative phosphorylation by nuclear myosin 1 protects cells from metabolic reprogramming and tumorigenesis in mice حسب Tomas Venit (17248420)

"…<p dir="ltr">Metabolic reprogramming is one of the hallmarks of tumorigenesis. Here, we show that nuclear myosin 1 (NM1) serves as a key regulator of cellular metabolism. …"

Concentrated photovoltaic thermal (CPVT) solar collector systems: Part I - Fundamentals, design considerations and current technologies حسب Sharaf, Omar Z.

"…Concentrated photovoltaic thermal (CPVT) solar collectors have been gaining ever-increasing attention from the scientific community and industrial developers due to their promising potential to pave the way for the penetration of solar energy into modern day power generation technologies. …"
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C1 neurons excite locus coeruleus and A5 noradrenergic neurons along with sympathetic outflow in rats حسب Abbott, S. B.

"…In additional rats, the retrotrap ezoid nucleus region wasdestroyed with substance P–saporin prior to lentivirus injection into the rostral ventrolateralmedulla, increasing the propor tion of C1 ChR2-expressing neurons (83%). …"
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SIRT1 promotes lipid metabolism and mitochondrial biogenesis in adipocytes and coordinates adipogenesis by targeting key enzymatic pathways حسب Yasser Majeed (9417974)

"…Supplementing preadipocytes with the NAD+ booster nicotinamide mononucleotide (NMN) during differentiation increased expression levels of leptin, SIRT1, and PGC-1α and its transcriptional targets, and reduced levels of pro-fibrotic collagens (Col6A1 and Col6A3) in a SIRT1-dependent manner. …"

Controversy and Debate: Questionable utility of the relative risk in clinical research: Paper 1: A call for change to practice حسب Suhail A., Doi

"…Methods We used mathematical derivation to determine if the RR is a measure of effect magnitude alone (i.e., a larger absolute value always indicating a stronger effect) or not. …"
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Controversy and Debate: Questionable utility of the relative risk in clinical research: Paper 1: A call for change to practice حسب Suhail A. Doi (9552474)

"…</p><h3>Methods</h3><p dir="ltr">We used mathematical derivation to determine if the RR is a measure of effect magnitude alone (i.e., a larger absolute value always indicating a stronger effect) or not. …"

Layered homologous compounds (ZnO)_<em>k</em>In₂O₃ (<i>k</i> = 3, 5, and 7) as novel photocatalysts for visible-light-driven photocatalytic degradat... حسب Abhishek R. Bhapkar (17726418)

"…UV–vis spectroscopy revealed the band gap widening with increasing ‘<i>k</i>’, while IZO-5 and IZO-7 exhibit lower PL emissions in the visible range. …"

Dynamic Properties of Water Confined in Graphene-Based Membrane: A Classical Molecular Dynamics Simulation Study حسب One-Sun Lee (1291293)

A SENSITIVE APPROACH TO DETERMINE THE HEALTH STATUS OF I-BEAMS BY MEASURING ITS NONLINEARITY THROUGH THE USE OF RAYLEIGH WAVES حسب Tse, Peter

"…The present study focusses on evaluating the health status of a 1018 steel I-beam using a new nonlinearity parameter defined for Rayleigh waves. …"
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PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications حسب Pramod Darvin (153341)

"…Understanding the mechanisms behind this PD-L1 overexpression in cancer stem cells is critical for developing more effective strategies for preventing immune evasion and increasing the efficacy of anti-PD-1/PD-L1 therapy. …"

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit, Masania

"…Mice with ectopic expression of uncoupling protein-1 (UCP1) in skeletal muscle exhibit a healthy aging phenotype with increased longevity and resistance to impaired metabolic health. …"
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit Masania (7164239)

"…<p dir="ltr">Mice with ectopic expression of uncoupling protein-1 (UCP1) in skeletal muscle exhibit a healthy aging phenotype with increased longevity and resistance to impaired metabolic health. …"

Characterisation of Pga1, a putative Candida albicans cell wall protein necessary for proper adhesion and biofilm formation حسب Malouf, Katia

"…Many of these factors are glycosylphosphatidylinositol-anchored cell surface antigenic determinant proteins. Pga1 is one such protein shown to be upregulated during cell wall regeneration. …"
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The Candida albicans Dse1 Protein Is Essential and Plays a Role in Cell Wall Rigidity, Biofilm Formation, and Virulence حسب Khalaf, Roy A.

"…The fungal pathogen Candida albicans is one of the leading causative agents of death in immunocompromised individuals. …"
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The contribution of autophagy in glioblastoma multiforme cells treated with human recombinant arginase I-induced arginine deprivation. (c2018) حسب El Jbeily, Elie

"…All this results in a poor survival rate in GBM patients, which doesn’t exceed 1 year. Therefore, there is a need for more selective and effective approaches, such as the use of human recombinant arginase I to selectively target cells that are auxotrophic to arginine. …"
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