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101
An examination of how climate change could affect the future spread of <i>Fusarium</i> spp. around the world, using correlative models to model the changes
منشور في 2023"…In this study, we hypothesize that crop diseases caused by <i>Fusarium</i> spp. will increase across all four corners of the world by 2050 and 2070 in response to future climate conditions. …"
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102
Exploring the Dynamic Interplay of Deleterious Variants on the RAF1–RAP1A Binding in Cancer: Conformational Analysis, Binding Free Energy, and Essential Dynamics
منشور في 2024"…Integrated machine learning algorithms showed that among the 134 mutations reported for these 2 proteins, only 13 and 35 were classified as deleterious mutations in <i>RAF1</i> and <i>RAP1P</i>, respectively. Moreover, one mutation in RAF1 reported elevated levels of binding between <i>RAF1</i> and <i>RAP1P</i> while in <i>RAP1A</i>, 7 mutations were reported to increase the binding affinity. …"
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103
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104
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105
Structural and Biophysical Characterization of Stable Alpha-Synuclein Oligomers
منشور في 2022"…The secondary structure analysis revealed that only HNE and ONE oligomers contain β-sheet content. In the seeding assay, both DA and ONE oligomers significantly accelerated the aggregation. …"
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106
Shear behaviour of one-way high strength plain and FRC slabs reinforced with basalt FRP bars
منشور في 2022"…The main test variable was the BFRP longitudinal reinforcement ratio with two ratios of 0.792 % and 1.27 %. Also, two slabs were cast with basalt macro fibers (BMF) at a volume fraction of 0.75 % to explore the effect of the added fibers on the shear capacity of the tested one-way slabs. …"
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107
iPads in the classroom: trials in a technical college in Qatar
منشور في 2015"…Over 80% of students reported positively on the iPad as being “helpful” to “very helpful” for learning new things and course materials, for increasing their interaction with online course materials and getting course information and for exploring additional material related to course topics. …"
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108
Adipocyte Enhancer-Binding Protein 1 (AEBP1) (a Novel Macrophage Proinflammatory Mediator) Overexpression Promotes and Ablation Attenuates Atherosclerosis in ApoE⁻′⁻ and LDLR⁻′⁻ Mi...
منشور في 2011"…Moreover, AEBP1 has been shown to promote macrophage inflammatory responsiveness by inducing nuclear factor (NF)-κB activity via IκBα downregulation. …"
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109
Morphological changes in amblyopic eyes in choriocapillaris and Sattler’s layer in comparison to healthy eyes, and in retinal nerve fiber layer in comparison to fellow eyes through...
منشور في 2021"…Purpose Establishing the reliability of a new method to check the mean retinal and choroidal reflectivity and using it to find retinal and choroid changes in amblyopia. …"
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110
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111
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112
Potential distribution of a noxious weed (<i>Solanum viarum</i> Du-nal), current status, and future invasion risk based on MaxEnt modeling
منشور في 2023"…Under climate change regimes, the highly suitable area for <i>S. viarum</i> increases by 2–9% under two Representative Concentration Pathways (RCP 4.5 and RCP 8.5). …"
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113
One-year experience of hybrid closed-loop system in children and adolescents with type 1 diabetes previously treated with multiple daily injections: drivers to successful outcomes
منشور في 2022"…TIR (70–180 mg/dL) increased from 46.9% at baseline to 71.9% at 1 month and remained above 70% during the 12 months of HCL use.…"
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114
Epidemiological and genetic characterization of pH1N1 and H3N2 influenza viruses circulated in MENA region during 2009–2017
منشور في 2019"…Furthermore, nucleotide variations were lower at the antigenic sites of pH1N1 viruses compared to H3N2 viruses, which experienced higher variability at the antigenic sites, reflecting the increased immunological pressure because of longer circulation and continuous vaccine changes. …"
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115
ROS-Mediated Autophagic Death in Glioblastoma Cells Upon Treatment by Human Recombinant Arginase I (Co)- PEG5000 [HuArgI (Co)-PEG5000]
منشور في 2021"…Our results first showed a significant increase in HuArgI (Co)-PEG5000 treated cells for both U251 and A172 in autophagosome formation; suggesting activation of autophagy in response to arginine deprivation. …"
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masterThesis -
116
Alterations in Beta Cell Identity in Type 1 and Type 2 Diabetes
منشور في 2019"…Dedifferentiation is well characterized by the decrease in expression of key β cell markers such as genes encoding major transcription factors, e.g., MafA, NeuroD1, Nkx6.1, and Foxo1, and an increase in atypical or “disallowed” genes for β cells such as lactate dehydrogenase, monocarboxylate transporter MCT1, or progenitor cell genes (Neurog3, Pax4, or Sox9). …"
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117
Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018)
منشور في 2018"…The addition of chloroquine, an autophagy inhibitor, increased the sensitivity of cells to [HuArgI (Co)-PEG5000]-mediated arginine depletion at earlier time points. …"
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masterThesis -
118
Rfg1, a protein related to the hypoxic repressor Rox1 of Saccharomyces cerevisiae, is a novel DNA binding repressor of filamentation in the pathogenic yeast, Candida albicans
منشور في 2001"…I have identified a repressor of hyphal growth in the pathogenic yeast Candida albicans. …"
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masterThesis -
119
Human recombinant arginase I (Co)-PEG5000 [HuArgI (Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human glioblastoma cells
منشور في 2015"…Inhibition of autophagy increased cell sensitivity to HuArgI (Co)-PEG5000 indicating that, following arginine deprivation, autophagy plays a protective role in GBM cells. …"
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120
Tuberculosis following programmed cell death receptor-1 (PD-1) inhibitor in a patient with non-small cell lung cancer. Case report and literature review
منشور في 2022"…Nonetheless, tuberculosis (TB) reactivation during their use is increasingly recognized and reported. Herein, we present a 58-year-old lady with advanced non-small cell lung cancer (NSCLC) ALK-negative, EGFR wild, and PD-L1 immune histochemistry (IHC) strongly positive in 95% of tumor cells, on ongoing treatment with Pembrolizumab as a first-line monotherapy. …"