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Neoadjuvant Chemotherapy Alters Neuropilin-1, PlGF, and SNAI1 Expression Levels and Predicts Breast Cancer Patients Response
Published 2019“…Unlike NRP-1, circulating PlGF was significantly increased (<i>p</i> = 0.014) in patients with a pathological complete response (pCR). …”
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Tryptophanyl-tRNA synthetase-1 (WARS-1) depletion and high tryptophan concentration lead to genomic instability in Caenorhabditis elegans
Published 2024“…More recently, mutations in the tryptophanyl-tRNA synthetase 1 (WARS1) have been linked to various human diseases, from intellectual disability to various types of cancer. …”
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Impacts of climate change on the global spread and habitat suitability of <i>Coxiella burnetii</i>: Future projections and public health implications
Published 2025“…<h3>Introduction</h3><p dir="ltr"><i><u>Coxiella burnetii</u></i><i><u>,</u></i> an intracellular zoonotic bacterium, affectsing various livestock and <u>wildlife</u> species and poses significant risks to human health. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…Flow cytometric analysis revealed that both fractions induced the accumulation of cells in the sub-G1 phase, increase in apoptotic cell death and chromatin condensation. …”
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Photoemission study of the electronic structure of LaFeAsO 1-xFx and LaFePO1-xFx
Published 2008“…Also, in going from LaFeAsO1-xF x to LaFePO1-xFx, the near-EF intensity increases reflecting the weakening of electron correlation.…”
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Rodent-borne zoonoses in Qatar: A possible One-Health framework for the intervention of future epidemic
Published 2023“…<p>The increasing frequency of spillover of zoonotic pathogens from animals to humans in recent years highlights a need to develop a more comprehensive framework to investigate and prevent pathogens of animal origin, including rodents. …”
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88
One Dimensional Seismic Site Response Analysis of United Arab Emirates
Published 2021Get full text
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Increased Frequency of Severe Hypoglycemia with the Modified-Release Gliclazide Compared to Glimepiride in Diabetic Older Adults; Propensity Score-Adjusted Analysis
Published 2022“…The risk of SHEA (Adjusted Odds Ratio AOR 6.74, p=0.002), falls (AOR 1.43, p=0.003), fractures (AOR 1.43, p=0.01), CVEA (AOR 1.66, p< 0.001), recurrent ED admission (AOR 1.39, p=0.002) were significantly higher. …”
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The emergence of new SARS-CoV-2 variant (Omicron) and increasing calls for COVID-19 vaccine boosters-The debate continues
Published 2022“…<p dir="ltr">The emergence of highly mutated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant Omicron (B.1.1.529) has ushered panic responses around the world due to its contagious and vaccine escape mutations. …”
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Treatment with decitabine induces the expression of stemness markers, PD-L1 and NY-ESO-1 in colorectal cancer: potential for combined chemoimmunotherapy
Published 2023“…Interestingly, in the metastatic 1872 Col cells treated with DAC, the expression of both PD-L1 and NY-ESO-1 was increased tenfold (*p = 0.0128) and fivefold (***p < 0.0001), respectively.…”
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ABCB1 (P-glycoprotein) and blood-brain barrier
Published 2006“…Furthermore, ABCB1 expression and/or functionality may modify drug efficacity or increase central adverse events. …”
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Stress granules counteract senescence by sequestration of PAI‐1
Published 2018“…PAI‐1 localization to SGs increases the translocation of cyclin D1 to the nucleus, promotes RB phosphorylation, and maintains a proliferative, non‐senescent state. …”
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Inositol 1,4,5-Trisphosphate Receptors in Hypertension
Published 2018“…Evidence supports a role for vascular aging in the development of hypertension involving an impairment in endothelial function together with an alteration in vascular smooth muscle cells (VSMCs) calcium homeostasis leading to increased myogenic tone. Changes in free intracellular calcium levels ([Ca<sup>2+</sup>]<sub><em>i</em></sub>) are mediated either by the influx of Ca<sup>2+</sup> from the extracellular space or release of Ca<sup>2+</sup> from intracellular stores, mainly the sarcoplasmic reticulum (SR). …”
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Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway
Published 2022“…Additionally, after β-catenin silencing, OA treatment significantly increased the expression of nuclear transcription factors SREBP-1 and TCF4, whereas Ex-4 significantly decreased this upregulation. …”
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Novel Thermo-Halotolerant Bacteria <i>Bacillus cabrialesii </i>Native to Qatar Desert: Enhancing Seedlings’ Growth, Halotolerance, and Antifungal Defense in Tomato
Published 2024“…</i> cerasiforme and promote seeds germination and seedlings growth under saline conditions. …”
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Which factor explains the life‐history of <i>Xanthium strumarium</i> L., an aggressive alien invasive plant species, along its altitudinal gradient?
Published 2022“…The X. strumarium exhibits late vegetative and reproductive phenology at higher altitudes, enabling them to occupy an empty niche and benefit from decreased competition for resource acquisition. The lower altitude plants show a higher growth rate (stem size increase, number of leaves, and leaf area) due to the higher nutrient availability. …”
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Flexural Response of Reinforced Concrete One-Way Slabs Embedded with Pet Bottles
Published 2023Get full text
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