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201
Epidemiology of herpes simplex virus type 1 in the United States: Systematic review, meta-analyses, and meta-regressions
منشور في 2024"…The pooled mean proportion of HSV-1 detection in genital herpes was 15.4% (95% CI: 10.8–20.6), increasing by 1.02-fold (95% CI: 1.00–1.04) per year. …"
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article -
202
Comparative proteomic analysis of a Candida albicans DSE1 mutant under filamentous and non-filamentous conditions
منشور في 2014"…The wild-type strain expressed Pra1, involved in pH response and zinc acquisition, Atg15, a lipase involved in virulence, and Sod1, required for oxidative stress tolerance, in addition to proteins involved in protein biosynthesis, explaining the increase in total protein content observed compared to the mutants strain. …"
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203
Proteomic analyses of the cell walls of candida albicans PGA1 and PIR32 null mutants. (c2017)
منشور في 2017"…The pir32 null strain on the other hand showed more pronounced phenotypes such as hyperfilamentation ability, and increased resistance to oxidative stress in part due to a two fold increase in chitin deposition. …"
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masterThesis -
204
NKX6.1 transcription factor: a crucial regulator of pancreatic β cell development, identity, and proliferation
منشور في 2020"…The importance of NKX6.1 as a crucial regulator in MPC specification into functional β cells directs attentions to further investigating its mechanism and enhancing NKX6.1 expression as a means to increase β cell function and mass. …"
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205
Unleashing the immune response to NY-ESO-1 cancer testis antigen as a potential target for cancer immunotherapy
منشور في 2022"…We propose that combination therapy to increase the efficacy of NY-ESO-1 specific immunotherapeutic interventions should be explored to unleash the immune response against NY-ESO-1 expressing tumors.…"
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206
Prehospital Intervals and In-Hospital Trauma Mortality: A Retrospective Study from a Level I Trauma Center
منشور في 2023"…</p><h3>Results</h3><p dir="ltr">A total of 1,455 patients were included, of which nearly one-quarter of patients required urgent and life-saving care at a trauma center (T1 activations). …"
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207
High fractional excretion of glycation adducts is associated with subsequent early decline in renal function in type 1 diabetes
منشور في 2020"…<div><p>Increased protein glycation, oxidation and nitration is linked to the development of diabetic nephropathy. …"
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208
Positive regulation of oxidative phosphorylation by nuclear myosin 1 protects cells from metabolic reprogramming and tumorigenesis in mice
منشور في 2023"…<p dir="ltr">Metabolic reprogramming is one of the hallmarks of tumorigenesis. Here, we show that nuclear myosin 1 (NM1) serves as a key regulator of cellular metabolism. …"
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209
Concentrated photovoltaic thermal (CPVT) solar collector systems: Part I - Fundamentals, design considerations and current technologies
منشور في 2015"…Concentrated photovoltaic thermal (CPVT) solar collectors have been gaining ever-increasing attention from the scientific community and industrial developers due to their promising potential to pave the way for the penetration of solar energy into modern day power generation technologies. …"
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210
C1 neurons excite locus coeruleus and A5 noradrenergic neurons along with sympathetic outflow in rats
منشور في 2012"…In additional rats, the retrotrap ezoid nucleus region wasdestroyed with substance P–saporin prior to lentivirus injection into the rostral ventrolateralmedulla, increasing the propor tion of C1 ChR2-expressing neurons (83%). …"
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article -
211
SIRT1 promotes lipid metabolism and mitochondrial biogenesis in adipocytes and coordinates adipogenesis by targeting key enzymatic pathways
منشور في 2021"…Supplementing preadipocytes with the NAD+ booster nicotinamide mononucleotide (NMN) during differentiation increased expression levels of leptin, SIRT1, and PGC-1α and its transcriptional targets, and reduced levels of pro-fibrotic collagens (Col6A1 and Col6A3) in a SIRT1-dependent manner. …"
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212
Controversy and Debate: Questionable utility of the relative risk in clinical research: Paper 1: A call for change to practice
منشور في 2020"…Methods We used mathematical derivation to determine if the RR is a measure of effect magnitude alone (i.e., a larger absolute value always indicating a stronger effect) or not. …"
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article -
213
Controversy and Debate: Questionable utility of the relative risk in clinical research: Paper 1: A call for change to practice
منشور في 2020"…</p><h3>Methods</h3><p dir="ltr">We used mathematical derivation to determine if the RR is a measure of effect magnitude alone (i.e., a larger absolute value always indicating a stronger effect) or not. …"
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214
Layered homologous compounds (ZnO)<sub><em>k</em></sub>In<sub>2</sub>O<sub>3</sub> (<i>k</i> = 3, 5, and 7) as novel photocatalysts for visible-light-driven photocatalytic degradat...
منشور في 2024"…UV–vis spectroscopy revealed the band gap widening with increasing ‘<i>k</i>’, while IZO-5 and IZO-7 exhibit lower PL emissions in the visible range. …"
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215
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216
A SENSITIVE APPROACH TO DETERMINE THE HEALTH STATUS OF I-BEAMS BY MEASURING ITS NONLINEARITY THROUGH THE USE OF RAYLEIGH WAVES
منشور في 2019"…The present study focusses on evaluating the health status of a 1018 steel I-beam using a new nonlinearity parameter defined for Rayleigh waves. …"
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217
PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
منشور في 2019"…Understanding the mechanisms behind this PD-L1 overexpression in cancer stem cells is critical for developing more effective strategies for preventing immune evasion and increasing the efficacy of anti-PD-1/PD-L1 therapy. …"
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218
Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…Mice with ectopic expression of uncoupling protein-1 (UCP1) in skeletal muscle exhibit a healthy aging phenotype with increased longevity and resistance to impaired metabolic health. …"
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article -
219
Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…<p dir="ltr">Mice with ectopic expression of uncoupling protein-1 (UCP1) in skeletal muscle exhibit a healthy aging phenotype with increased longevity and resistance to impaired metabolic health. …"
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220
Characterisation of Pga1, a putative Candida albicans cell wall protein necessary for proper adhesion and biofilm formation
منشور في 2015"…Many of these factors are glycosylphosphatidylinositol-anchored cell surface antigenic determinant proteins. Pga1 is one such protein shown to be upregulated during cell wall regeneration. …"
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article