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141
Emtricitabine/rilpivirine/tenofovir disoproxil fumarate for the treatment of HIV-1 infection in adults
Published 2015“…Clinical trial reports were selected, extracted and analyzed to include relevant and recent ones. Selected English-language trials were limited to those with human subjects and included both safety and efficacy outcomes. …”
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142
The carboxy terminal coiled-coil modulates Orai1 internalization during meiosis
Published 2021“…SOCE is tightly regulated during meiosis, including internalization of the SOCE channel, Orai1. Orai1 is a four-pass membrane protein with cytosolic N- and C-termini. …”
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143
Editorial: Dynamic Biomarkers of Response to Anti-Immune Checkpoint Inhibitors in Cancer
Published 2021“…In current clinical practice only PD-L1 expression in tumor tissues is used as predictive biomarker of response to PD-1 immune checkpoint blockade. …”
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144
Guanine glycation repair by DJ-1/Park7 and its bacterial homologs
Published 2017“…DJ-1–depleted cells displayed increased levels of glycated DNA, DNA strand breaks, and phosphorylated p53. …”
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145
Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema
Published 2010“…The effects of increased endogenous ceramides could be offset by sphingosine 1-phosphate (S1P), a prosurvival by-product of ceramide metabolism. …”
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146
Higher serum leptin level in women than in nen with type 1 diabetes
Published 2002“…In humans, serum leptin concentrations are increased in relation to increased body fat content. …”
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147
Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions
Published 2019“…Consistently, inactivating Iqgap1 normalizes Rac1 GTP-loading, and reduces inflammation and arthritis in GGTase-I-deficient mice, as well as prevents statins from increasing Rac1 GTP-loading and cytokine production in macrophages. …”
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148
A decoding algorithm for I-Q space-time coded systems in fadingenvironments
Published 2000“…This paper presents the decoding of the I-Q space-time (ST) codes. The decoding problem of I-Q ST codes is formulated. …”
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149
DUSP1 Is a Potential Marker of Chronic Inflammation in Arabs with Cardiovascular Diseases
Published 2018“…Multivariate logistic regression analysis showed that DUSP1 and hsCRP are independently associated with CVD in the studied population, as reflected by 2-fold and 1.5-fold increased risks with increased levels of DUSP1 and hsCRP, respectively. …”
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150
The Effect of HuArgI (Co)-PEG5000 on The Migration of Ovarian Cancer
Published 2020“…In this study, we hypothesized that HuArgI (Co)- PEG5000 can decrease the migration of ovarian cancer cells. …”
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151
The effect of GLP-1R agonists on the medical triad of obesity, diabetes, and cancer
Published 2024“…While other GLP-1R agonists have shown promising outcomes in mitigating cancer progression, the association between some GLP-1R agonists and an increased risk of cancer remains a topic requiring more profound investigation. …”
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Circulating exosomal immuno-oncological checkpoints and cytokines are potential biomarkers to monitor tumor response to anti-PD-1/PD-L1 therapy in non-small cell lung cancer patien...
Published 2023“…Non-responding patients showed a significant increase in exosomal-PD-L1 (p=0.0078). Furthermore, responding-patients without liver-metastasis showed significant-upregulation of PD-1 (p=0.0070), and downregulation of ULBP1 (p=0.0137) and Siglec-7 (p=0.0037). …”
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Flexural strengthening of one-way reinforced concrete slabs using near surface-mounted BFRP bars
Published 2024“…<p>This study examines the flexural behavior of reinforced concrete (RC) one-way slabs strengthened with near-surface mounted (NSM) basalt fiber-reinforced polymer (BFRP) bars. …”
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156
Pregnant Women's experiences with intimate partner violence one year after the COVID‐19 pandemic in Jordan
Published 2023“…There were statistically significant (<i>p </i>≤ 0.05) higher mean DVQST scores for control IPV and psychological IPV during the pandemic (control IPV mean = 9.78, psychological mean = 7.03) versus before the pandemic (control IPV mean = 8.95, psychological mean = 6.62). …”
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157
Regulation of the aryl hydrocarbon receptor in cancer and cancer stem cells of gynecological malignancies: An update on signaling pathways
Published 2022“…One of the important pathways that mediates the metabolism and bioactivation of these environmental chemicals is the transcription factor, aryl hydrocarbon receptor (AhR). …”
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158
Evaluation of the mode I plastic zone size at the crack tip using RKPM and FEM
Published 2017“…In this study, it is proposed to obtain the mode I plastic zone size and shape at the crack-tip in a work-hardening material using RKPM. …”
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159
Combined Noncoding RNA-mRNA Regulomics Signature in Reprogramming and Pluripotency in iPSCs
Published 2022“…Introducing miRNAs, such as miR-294 and miR302/3667, with reprogramming factors, has shown to increase iPSC colony formation. Previously, we identified five transcription factors, GBX2, NANOGP8, SP8, PEG3, and ZIC1, which may boost iPSC generation. …”
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IL-1 stimulates ceramide accumulation without inducing apoptosis in intestinal epithelial cells
Published 2002“…Background: In inflammatory bowel disease (IBD), cytokine levels (such as interleukin-1 (IL-1)) are elevated. We have shown previously that IL-1 activates phospholipid signaling pathways in intestinal epithelial cells (IEC), leading to increased ceramide levels. …”
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