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221
Prehospital Intervals and In-Hospital Trauma Mortality: A Retrospective Study from a Level I Trauma Center
منشور في 2023"…</p><h3>Results</h3><p dir="ltr">A total of 1,455 patients were included, of which nearly one-quarter of patients required urgent and life-saving care at a trauma center (T1 activations). …"
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222
High fractional excretion of glycation adducts is associated with subsequent early decline in renal function in type 1 diabetes
منشور في 2020"…<div><p>Increased protein glycation, oxidation and nitration is linked to the development of diabetic nephropathy. …"
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223
Positive regulation of oxidative phosphorylation by nuclear myosin 1 protects cells from metabolic reprogramming and tumorigenesis in mice
منشور في 2023"…<p dir="ltr">Metabolic reprogramming is one of the hallmarks of tumorigenesis. Here, we show that nuclear myosin 1 (NM1) serves as a key regulator of cellular metabolism. …"
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224
Concentrated photovoltaic thermal (CPVT) solar collector systems: Part I - Fundamentals, design considerations and current technologies
منشور في 2015"…Concentrated photovoltaic thermal (CPVT) solar collectors have been gaining ever-increasing attention from the scientific community and industrial developers due to their promising potential to pave the way for the penetration of solar energy into modern day power generation technologies. …"
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225
C1 neurons excite locus coeruleus and A5 noradrenergic neurons along with sympathetic outflow in rats
منشور في 2012"…In additional rats, the retrotrap ezoid nucleus region wasdestroyed with substance P–saporin prior to lentivirus injection into the rostral ventrolateralmedulla, increasing the propor tion of C1 ChR2-expressing neurons (83%). …"
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226
SIRT1 promotes lipid metabolism and mitochondrial biogenesis in adipocytes and coordinates adipogenesis by targeting key enzymatic pathways
منشور في 2021"…Supplementing preadipocytes with the NAD+ booster nicotinamide mononucleotide (NMN) during differentiation increased expression levels of leptin, SIRT1, and PGC-1α and its transcriptional targets, and reduced levels of pro-fibrotic collagens (Col6A1 and Col6A3) in a SIRT1-dependent manner. …"
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227
Controversy and Debate: Questionable utility of the relative risk in clinical research: Paper 1: A call for change to practice
منشور في 2020"…Methods We used mathematical derivation to determine if the RR is a measure of effect magnitude alone (i.e., a larger absolute value always indicating a stronger effect) or not. …"
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228
Controversy and Debate: Questionable utility of the relative risk in clinical research: Paper 1: A call for change to practice
منشور في 2020"…</p><h3>Methods</h3><p dir="ltr">We used mathematical derivation to determine if the RR is a measure of effect magnitude alone (i.e., a larger absolute value always indicating a stronger effect) or not. …"
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229
Dynamic Properties of Water Confined in Graphene-Based Membrane: A Classical Molecular Dynamics Simulation Study
منشور في 2019"…We also calculated the reorientational correlation time of the water molecules, and we found that the rotational motion of confined water inside the membrane is anisotropic and the reorientational correlation time of confined water is slower than that of bulk water. …"
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230
Layered homologous compounds (ZnO)<sub><em>k</em></sub>In<sub>2</sub>O<sub>3</sub> (<i>k</i> = 3, 5, and 7) as novel photocatalysts for visible-light-driven photocatalytic degradat...
منشور في 2024"…UV–vis spectroscopy revealed the band gap widening with increasing ‘<i>k</i>’, while IZO-5 and IZO-7 exhibit lower PL emissions in the visible range. …"
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231
The contribution of autophagy in glioblastoma multiforme cells treated with human recombinant arginase I-induced arginine deprivation. (c2018)
منشور في 2018"…The activation of LC3-I peaked in control conditions (chloroquine treatment), considerably decreased in cells treated with the highest arginase concentration, then increased again in cells treated with both arginase at its highest concentration and chloroquine. mTOR is active in control cells, while at highest arginase concentration there is an inactivation of mTOR resulting in the activation of autophagy. …"
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masterThesis -
232
A SENSITIVE APPROACH TO DETERMINE THE HEALTH STATUS OF I-BEAMS BY MEASURING ITS NONLINEARITY THROUGH THE USE OF RAYLEIGH WAVES
منشور في 2019"…The present study focusses on evaluating the health status of a 1018 steel I-beam using a new nonlinearity parameter defined for Rayleigh waves. …"
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233
Targeting arginine auxotrophy in pancreatic cancer cells using human recombinant arginase I-induced arginine deprivation. (c2017)
منشور في 2017"…Pancreatic cancer (PC) is a highly aggressive solid malignancy with no efficient therapy. It is one of the deadliest cancer types since its mortality rate per year is nearly equal to its incidence rate. …"
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masterThesis -
234
PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
منشور في 2019"…Understanding the mechanisms behind this PD-L1 overexpression in cancer stem cells is critical for developing more effective strategies for preventing immune evasion and increasing the efficacy of anti-PD-1/PD-L1 therapy. …"
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235
Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…Mice with ectopic expression of uncoupling protein-1 (UCP1) in skeletal muscle exhibit a healthy aging phenotype with increased longevity and resistance to impaired metabolic health. …"
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236
Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…<p dir="ltr">Mice with ectopic expression of uncoupling protein-1 (UCP1) in skeletal muscle exhibit a healthy aging phenotype with increased longevity and resistance to impaired metabolic health. …"
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237
Characterisation of Pga1, a putative Candida albicans cell wall protein necessary for proper adhesion and biofilm formation
منشور في 2015"…Many of these factors are glycosylphosphatidylinositol-anchored cell surface antigenic determinant proteins. Pga1 is one such protein shown to be upregulated during cell wall regeneration. …"
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238
The Candida albicans Dse1 Protein Is Essential and Plays a Role in Cell Wall Rigidity, Biofilm Formation, and Virulence
منشور في 2011"…The fungal pathogen Candida albicans is one of the leading causative agents of death in immunocompromised individuals. …"
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239
Health in times of uncertainty in the eastern Mediterranean region, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013
منشور في 2016"…However, diarrhoeal diseases were the leading cause of death in Somalia (186·7 deaths per 100 000 people) in 2013, which decreased by 26·9% since 1990. …"
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240
The Stakeholders’ Perceptions about the Effectiveness of iPads Integrations in Third Grade English Classes in a Private School in Sharjah, UAE
منشور في 2023"…The purpose of this study is to examine the attitude of parents, teachers, and leaders of the iPad’s integrations in third grade English classes in one of the private schools in Sharjah. …"
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