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Circulating exosomal immuno-oncological checkpoints and cytokines are potential biomarkers to monitor tumor response to anti-PD-1/PD-L1 therapy in non-small cell lung cancer patien...
Published 2023“…Non-responding patients showed a significant increase in exosomal-PD-L1 (p=0.0078). Furthermore, responding-patients without liver-metastasis showed significant-upregulation of PD-1 (p=0.0070), and downregulation of ULBP1 (p=0.0137) and Siglec-7 (p=0.0037). …”
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Enhanced glucose uptake in phenylbutyric acid-treated 3T3-L1 adipocytes
Published 2018“…PARK7 protein expression increased with PBA. Treating differentiated adipocytes with PBA did not alter their differentiation status, but decreased the leptin to adiponectin ratio. …”
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165
Flexural strengthening of one-way reinforced concrete slabs using near surface-mounted BFRP bars
Published 2024“…<p>This study examines the flexural behavior of reinforced concrete (RC) one-way slabs strengthened with near-surface mounted (NSM) basalt fiber-reinforced polymer (BFRP) bars. …”
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Pregnant Women's experiences with intimate partner violence one year after the COVID‐19 pandemic in Jordan
Published 2023“…There were statistically significant (<i>p </i>≤ 0.05) higher mean DVQST scores for control IPV and psychological IPV during the pandemic (control IPV mean = 9.78, psychological mean = 7.03) versus before the pandemic (control IPV mean = 8.95, psychological mean = 6.62). …”
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An empirical evaluation of the technology cycle time indicator as ameasure of the pace of technological progress in superconductortechnology
Published 1999“…This study found the trend in TCT changed abruptly from gradually increasing (slowing in cycle time) to steadily decreasing (speeding up in cycle time) following the discovery of high-temperature superconductors. …”
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Regulation of the aryl hydrocarbon receptor in cancer and cancer stem cells of gynecological malignancies: An update on signaling pathways
Published 2022“…One of the important pathways that mediates the metabolism and bioactivation of these environmental chemicals is the transcription factor, aryl hydrocarbon receptor (AhR). …”
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IL-1 stimulates ceramide accumulation without inducing apoptosis in intestinal epithelial cells
Published 2002“…Neither IL-1 nor ceramide induced apoptosis in IEC, but they increased bcl-2 levels and decreased bax and p21 levels without affecting bcl-x and p53 levels. …”
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Capacity allocation for voice over IP networks using maximum waiting time models
Published 2004“…In this work, a new capacity allocation method based on the maximum waiting time model is explored. It is established from the following concept: by providing statistical quality guarantees to those packets that experience the maximum waiting time among all packets of the active voice connections, all other packets are implicitly protected from excess delay and, thus, from service degradation. …”
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171
Evaluation of the mode I plastic zone size at the crack tip using RKPM and FEM
Published 2017“…In this study, it is proposed to obtain the mode I plastic zone size and shape at the crack-tip in a work-hardening material using RKPM. …”
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172
Combined Noncoding RNA-mRNA Regulomics Signature in Reprogramming and Pluripotency in iPSCs
Published 2022“…Introducing miRNAs, such as miR-294 and miR302/3667, with reprogramming factors, has shown to increase iPSC colony formation. Previously, we identified five transcription factors, GBX2, NANOGP8, SP8, PEG3, and ZIC1, which may boost iPSC generation. …”
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Kefir induces cell-cycle arrest and apoptosis in HTLV-1-negative malignant T-lymphocytes
Published 2011“…Purpose: The present study investigates the effect of a cell-free fraction of kefir on CEM and Jurkat cells, which are human T-lymphotropic virus type I (HTLV-1)-negative malignant T-lymphocytes. Methods: Cells were incubated with different kefir concentrations. …”
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Percutaneous coronary intervention can be safely performed with left ventricular thrombus without increasing stroke risk: A 5-year retrospective review using real-world data
Published 2023“…<h3>Introduction</h3><p dir="ltr">Left ventricular thrombus (LVT) increases the risk of ischemic stroke. However, it remains uncertain if the percutaneous coronary intervention (PCI) in the confirmed LVT setting further augments the stroke risk. …”
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Founder Mutation in N Terminus of Cardiac Troponin I Causes Malignant Hypertrophic Cardiomyopathy
Published 2020“…<h3>Background</h3><p dir="ltr">Cardiac troponin I (<i>TNNI3</i>) gene mutations account for 3% of hypertrophic cardiomyopathy and carriers have a heterogeneous phenotype, with increased risk of sudden cardiac death (SCD). …”
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Characterization of Dse1 a candida albicans cells wall protein. (c2009)
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Decoding the Therapeutic Potential of [HuArgI (Co)-PEG5000] Arginase Treatment
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178
The SREBP-dependent regulation of cyclin D1 coordinates cell proliferation and lipid synthesis
Published 2022“…We have previously demonstrated that one of these transcription factors, SREBP1, is stabilized and remains associated with target promoters during mitosis, suggesting that the expression of these target genes could be important as cells enter G1 and transcription is restored. …”
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Deficiency in the endocytic adaptor proteins PHETA1/2 impair renal and craniofacial development
Published 2020“…Deficiency of pheta1/2 resulted in dysregulation of cathepsin K, which led to an increased abundance of type II collagen in craniofacial cartilages, a marker of immature cartilage extracellular matrix. …”
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Designing Low Frequency I.C Filter Using Pseudo Resistor for Biopotential Measurements
Published 2010Get full text
doctoralThesis