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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…From this and previous transcriptomic studies, signaling involved in enhanced removal of MG-modified protein is likely increased HSPB1-directed HUWE1 ubiquitination through eIF2α-mediated, ATF5-induced increased expression of HSPB1. …"
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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies
منشور في 2021"…Recent studies specified the overexpression of V-domain Ig suppressor of T-cell activation (VISTA) and Aryl Hydrocarbon Receptor (AHR) in melanoma. …"
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Ferroelectric Properties and Electrocaloric Effect in Dy2O3 Substitution on Lead-Free (Na0.5 Bi0.5)0.94 Ba0.06TiO3 Ceramic
منشور في 2023"…Using the direct EC measurement, the ceramic corresponding to y = 0.02 exhibited a significant EC response, where ΔT = 1.2 K under 5 kV/mm. The incorporation of Dy was found to enhance the EC responsivity coefficient ζ = iT/ΔE), with a best value of ζ = 0.24 K.mm/kV for y = 0.02.…"
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4
Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov...
منشور في 2023"…At the 7th month, there was a significant decline in antibody responses among VN individuals, but not NI individuals, with a minimum decrease of 3.7-fold (p < 0.001). Among VN individuals, anti-S1 IgA levels began to decrease significantly (1.4-fold; p = 0.007) after two months, and both NtAb and S-RBD IgG levels began to decline significantly (NtAb: 2.0-fold; p = 0.042, S-RBD IgG: 2.4-fold; p = 0.035) after three months. …"
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Global, regional, and national burden of household air pollution, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
منشور في 2025"…The rate of HAP-attributable DALYs was higher for males (1530·5, 1023·4–2263·6) than for females (1318·5, 866·1–1977·2). …"
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Empirical evaluation of change in crash risk due to lane marking reallocation: A case study in Kochi City, Japan
منشور في 2023"…However, such changes could influence driver behavior. Thus, there is a tradeoff between efficiency and safety. Through a case study in Kochi City, Japan, this study evaluated the change in crash risk caused by a lane marking reallocation. …"
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8
Influence of temperature on tire-pavement noise in hot climates: Qatar case
منشور في 2021"…This temperature correction factor is developed based on the local environment (temperature varying from 5 °C to 35 °C) and generally varies with different pavements. …"
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9
A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
منشور في 2025"…We envisage that the NB2E3 nanobody-2× Mpro biosensor engineered here will be useful in drug discovery and functional characterization of Mpro mutants in newly emerging SARS-CoV-2 variants as well as in detecting SARS-CoV-2 infection in a point-of-care testing (POCT) format.…"
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10
Non-linear relationship between real commodity price volatility and real effective exchange rate: The case of commodity-exporting countries
منشور في 2019"…However, for periods when a country is better integrated financially, we observe a decrease in the impact of real commodity price volatility on REER, especially for the two panels of food and beverages as well as energy. …"
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11
Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants
منشور في 2017"…Global age-standardised prevalence of raised blood pressure was 24·1% (21·4–27·1) in men and 20·1% (17·8–22·5) in women in 2015. …"
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Exploring Beyond Numeric Weight Loss: The Metabolic Effects of Semaglutide.
منشور في 2025"…Also, it enhanced glycemic control, as evidenced by significant reductions in hemoglobin A1C (HbA1c) with the 0.5 mg and 1.0 mg doses. From a baseline range of 8.1–8.7%, 0.5mg dose lowered HbA1c by 1.2–1.5%, while the 1.0 mg dose reduced it by 1.4–1.8%. …"
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Temporal patterns of cancer burden in Asia, 1990–2019: a systematic examination for the Global Burden of Disease 2019 study
منشور في 2024"…FindingsAll cancers combined claimed an estimated 5.6 million [95% uncertainty interval, 5.1–6.0 million] lives in Asia with 9.4 million [8.6–10.2 million] incident cases and 144.7 million [132.7–156.5 million] DALYs in 2019. …"
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Trends in the global, regional, and national burden of oral conditions from 1990 to 2021: a systematic analysis for the Global Burden of Disease Study 2021
منشور في 2025"…Increasing counts of prevalent cases and DALYs were noted for all oral conditions but untreated caries of deciduous teeth (no percentage change in prevalence or DALYs) and orofacial clefts (–68·3% [–79·3 to –46·5] decrease in DALYs). …"
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High flow nasal oxygen (HFNO) in the treatment of COVID-19 infection of adult patients from – An emergency perspective: A systematic review and meta-analysis
منشور في 2023"…Our statistical analysis has shown that significantly lower ROX index (5.07 ± 1.66, p = 0.028) and PaO2/FiO2 (100 ± 27.51, p = 0.031) are associated with HFNO failure, while a significantly lower respiratory rate (RR) (23.17 ± 4.167, p = 0.006) is associated with HFNO success. …"
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Tranexamic Acid for Traumatic Injury in the Emergency Setting: A Systematic Review and Bias-Adjusted Meta-Analysis of Randomized Controlled Trials
منشور في 2024"…Researchers searched Medline, Embase, and Cochrane Central for randomized controlled trials comparing TXA’s effects to a placebo in emergency trauma cases. The primary endpoint was 1-month mortality. …"
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Influenza prevalence and vaccine efficacy among diabetic patients in Qatar
منشور في 2023"…Among the typed IVA-positive cases, 33.4% were H1N1, and 7.7% were H3N2. A significant decrease in influenza infections was reported in vaccinated DM patients (14.5%) when compared to non-vaccinated patients (18.9%) (p-value = 0.006). …"
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Human health risks associated with the consumption of groundwater in the Gaza Strip
منشور في 2023"…For all metals and metalloids analyzed, HQ were below one (HQ1) indicating no risk; however, Sr presented an HQ 95th percentile equal to 0.19. …"
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Influence of shelf-life duration on mechanical, thermal and shape recovery motion derivatives of shape memory polyurethane
منشور في 2024"…The present research, therefore explores the effect of shelf life on mechanical, thermal and shape recovery performance of polyurethane (PU) based shape memory polymer (SMP). Experimental samples S1, S3, S5 and S10 were prepared from polymer pellets that were stored for 1,3,5 and 10-year time duration respectively. …"
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Regional variations in incidence of surgical site infection and associated risk factors in women undergoing cesarean section: A systematic review and Meta-Analysis
منشور في 2025"…The SSI incidence in LMICs was 8.0 % (95 % CI: 6.0 %–10.0 %) with moderate certainty, while the incidence in HICs was 5.0 % (95 % CI: 4.0 %–7.0 %) with low certainty. …"
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